Antisense News and Research

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Antisense is the non-coding strand in double-stranded DNA. The antisense strand serves as the template for mRNA synthesis.
Inhibition of SARS-CoV-2 with antisense oligonucleotides

Inhibition of SARS-CoV-2 with antisense oligonucleotides

Research underlines SARS-CoV-2 N-terminal domain of Nsp1 as a potential drug target

Research underlines SARS-CoV-2 N-terminal domain of Nsp1 as a potential drug target

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

Evidence of SARS-CoV-2 coronavirus particles in heart tissue

Evidence of SARS-CoV-2 coronavirus particles in heart tissue

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Researchers identify new mechanism that causes leukemia

Researchers identify new mechanism that causes leukemia

FDA approves new treatment option for patients with rare Duchenne muscular dystrophy mutation

FDA approves new treatment option for patients with rare Duchenne muscular dystrophy mutation

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

Researchers develop new therapeutic approach to treat CLN3 Batten disease

Researchers develop new therapeutic approach to treat CLN3 Batten disease

Neurotransmitter-derived lipidoids help carry drugs across the blood-brain barrier in mice

Neurotransmitter-derived lipidoids help carry drugs across the blood-brain barrier in mice

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Arcturus and Duke-NUS announce approval of clinical trials for COVID-19 vaccine candidate

Arcturus and Duke-NUS announce approval of clinical trials for COVID-19 vaccine candidate

Experimental drug for rare ALS shows promise in early clinical trial

Experimental drug for rare ALS shows promise in early clinical trial

Structure of the full SARS-CoV-2 RNA genome in infected cells

Structure of the full SARS-CoV-2 RNA genome in infected cells

Researchers develop a potential treatment approach for Pelizaeus-Merzbacher disease

Researchers develop a potential treatment approach for Pelizaeus-Merzbacher disease

Scientists discover mechanism involving key protein that predicts cancer progression and relapse

Scientists discover mechanism involving key protein that predicts cancer progression and relapse

Researchers develop potential new therapy for common form of muscular dystrophy

Researchers develop potential new therapy for common form of muscular dystrophy

Parkinson's disease breakthrough seen in mouse model

Parkinson's disease breakthrough seen in mouse model

New therapeutic approach for Parkinson’s and other neurodegenerative diseases

New therapeutic approach for Parkinson’s and other neurodegenerative diseases

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome