Antisense News and Research

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Antisense is the non-coding strand in double-stranded DNA. The antisense strand serves as the template for mRNA synthesis.
Novel experimental drug designed to silence FUS gene may help treat ALS

Novel experimental drug designed to silence FUS gene may help treat ALS

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

Study involving a rat model offers potential treatment for Alexander disease

Study involving a rat model offers potential treatment for Alexander disease

$9 million grant from ASAP initiative to help advance research on Parkinson’s disease treatments

$9 million grant from ASAP initiative to help advance research on Parkinson’s disease treatments

Research reveals components of Sinbis virus ribonucleoproteins

Research reveals components of Sinbis virus ribonucleoproteins

Research reveals nucleolar RNA interference based on C. elegans as a model organism

Research reveals nucleolar RNA interference based on C. elegans as a model organism

Design of mRNA vaccines to combat COVID-19

Design of mRNA vaccines to combat COVID-19

The role of nanomaterials during the COVID-19 pandemic

The role of nanomaterials during the COVID-19 pandemic

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

Antisense oligonucleotides engineered to inhibit SARS-CoV-2

Antisense oligonucleotides engineered to inhibit SARS-CoV-2

New study identifies novel compound as promising pan-coronavirus drug candidate

New study identifies novel compound as promising pan-coronavirus drug candidate

Innovative therapeutic platform for blood-to-brain delivery of antisense oligonucleotide therapy

Innovative therapeutic platform for blood-to-brain delivery of antisense oligonucleotide therapy

Uncovering cellular mechanism related to gene silencing therapies

Uncovering cellular mechanism related to gene silencing therapies

New components for oligonucleotide drugs show safety, efficacy in treating spinal muscular atrophy

New components for oligonucleotide drugs show safety, efficacy in treating spinal muscular atrophy

UMSOM researchers develop two accurate, rapid diagnostic tests for COVID-19

UMSOM researchers develop two accurate, rapid diagnostic tests for COVID-19

What makes the elderly more susceptible to SARS-CoV-2 infection?

What makes the elderly more susceptible to SARS-CoV-2 infection?