Antiviral Drug News and Research

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Drinking cranberry juice may fight that tummy bug

A new study suggests that cranberry juice, a well documented remedy to help prevent urinary tract infections, may also work against gastrointestinal viruses.

8 Jun 2005

Biota makes major antiviral discovery

Biota Holdings Limited announced today that it has discovered a new class of orally-effective, potent antivirals against RSV (respiratory syncytial virus) infection.

7 Jun 2005

Cranberry juice may be effective in treating a number of gastrointestinal viruses

Cranberry juice, long considered a home remedy for urinary tract infections, may also be effective against a number of gastrointestinal viruses according to researchers from St. Francis College in Brooklyn, New York. They report their findings today at the 105th General Meeting of the American Society for Microbiology.

6 Jun 2005

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

In the latest version of the hide-and-seek game between pathogens and the hosts they infect, researchers have found that a virus appears to cloak itself with a recently discovered gene silencing device to evade detection and destruction by immune cells.

3 Jun 2005

Stronger version of chickenpox vaccine cuts incidence and severity of shingles in older adults

In one of the largest adult vaccine clinical trials ever, researchers have found that an experimental vaccine against shingles (zoster vaccine) prevented about half of cases of shingles--a painful nerve and skin infection--and dramatically reduced its severity and complications in vaccinated persons who got the disease. The findings appear in the June 2 issue of The New England Journal of Medicine.

1 Jun 2005

Bioniche Life Sciences granted European patent

Bioniche Life Sciences has announced that it has had another patent granted on its core technology: Mycobacterial Cell Wall-DNA Complex (MCC). The European Patent Organization (EPO) granted the patent: - "Composition and Method for Inducing Apoptosis in Prostate Cancer Cells" (EPO1165106)

30 May 2005

WIN compound - a prototype drug for curing colds - is showing so much promise

An antiviral compound that wiggles its way into the common cold virus may provide one piece of the solution to halting the infection, say Purdue University scientists.

25 May 2005

Vietnam reports another bird flu death

A death of a man from bird flu in Vietnam's Northern Province, has brought the total deaths in the country since late 2003 to 38.

23 May 2005

WHO says world must prepare for bird flu pandemic

Reports of disturbing changes to the H5N1 virus circulating in Asia is causing great concern and has prompted the World Health Organization (WHO) to urge countries to prepare for a influenza pandemic.

22 May 2005

FDA recommends approval of the investigational anti-HIV drug tipranavir

Boehringer Ingelheim today announced that the U.S. Food and Drug Administration's (FDA) Antiviral Drugs Advisory Committee recommended the approval of the investigational anti-HIV drug tipranavir (11-3). Tipranavir is a non-peptidic protease inhibitor that requires boosting with low-dose ritonavir and must be used in combination with other antiretroviral agents.

20 May 2005

NIAID has awarded 10 grants and 2 contracts totaling approximately $27 million to fund development of new therapeutics and vaccines against bioterrorism

The National Institute of Allergy and Infectious Diseases (NIAID) has awarded 10 grants and 2 contracts totaling approximately $27 million to fund development of new therapeutics and vaccines against some of the most deadly agents of bioterrorism including anthrax, botulinum toxin, Ebola virus, pneumonic plague, smallpox and tularemia.

11 May 2005

Small number of genes can predict response to chronic hepatitis C therapy

For the first time, physicians at University Health Network and University of Toronto have identified a small subset of genes that can predict whether a patient with chronic Hepatitis C will be able to respond to current treatments.

2 May 2005

Respiratory syncytial virus affects the elderly and high-risk adults as much as influenza

Respiratory syncytial virus (RSV), primarily seen as a cause of illness in infants and children, often affects the elderly and high-risk adults as much as influenza, a study by University of Rochester Medical Center researchers demonstrates.

27 Apr 2005

How Ebola virus infects cells - discovery

Ebola virus reproduction in laboratory-grown cells is severely hampered by enzyme-inhibiting chemicals, and these chemicals deserve further study as possible treatments for Ebola virus infections in humans, report scientists supported in part by the National Institute of Allergy and Infectious Diseases (NIAID).

23 Apr 2005

Viramidine demonstrates anti-HCV Genotype 1 activity that compares favorably to Ribavirin

Dose-limiting anemia can be a prominent adverse event of therapy with pegylated interferon and ribavirin. This dose-ranging study examined whether viramidine, a liver-targeting prodrug of ribavirin, may be a safer alternative when used in combination with pegylated interferon alfa-2a/ PEG-IFN (Pegasys).

23 Apr 2005

Scientists have discovered the mechanism that enables some CD4 T cells - the main target of HIV - to thwart the virus

The discovery, reported on April 13 in the online version of Nature, could open the door to an entirely new strategy for preventing the spread of HIV infection in the body's cells, according to the senior author of the study, Gladstone Institute of Virology and Immunology Director Warner C. Greene, MD, PhD.

13 Apr 2005