Aortic Stenosis News and Research

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Researchers identify link between narrowed heart valves and special lipoprotein in blood

Researchers at the University of Copenhagen, Herlev Hospital and Rigshospitalet have identified a clear link between narrowed heart valves and a special lipoprotein in the blood. In the long term, the research may well help to prevent valvular heart disease.

13 Nov 2013

Landmark clinical trial of artificial aortic heart valve shows positive results

Loyola University Medical Center is the only Chicago hospital participating in a landmark clinical trial of an artificial aortic heart valve that does not require open heart surgery.

From Medtronic 8 Nov 2013

Clinical trial finds COREVALVE reduces rate of death, stroke in patients with aortic stenosis

In a clinical trial, a self-expanding transcatheter aortic valve met the key performance objective of reducing death and stroke in patients with severe aortic stenosis at "extreme risk" for surgery.Results of the COREVALVE EXTREME RISK trial were presented today at the 25th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.

30 Oct 2013

Bluhm Institute enrolls first patient in SALUS trial to evaluate movable, non-metallic heart valve

Northwestern's Bluhm Cardiovascular Institute has enrolled its first participant in SALUS, a clinical trial studying the effectiveness of a prosthetic aortic heart valve that can be placed without open-heart surgery.

10 Oct 2013

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

The Cardiovascular Research Foundation (CRF) has announced the late breaking trials and first report investigations that will be presented at next month's Transcatheter Cardiovascular Therapeutics (TCT) 2013 scientific symposium.

21 Sep 2013

Boston Scientific announces positive results from REPRISE II clinical trial of Lotus Valve System

Boston Scientific Corporation reported favorable six-month results from the first 60 patients enrolled in the REPRISE II clinical trial evaluating the safety and performance of the Lotus™ Valve System in symptomatic patients with severe aortic stenosis considered at high risk for surgical valve replacement.

17 Sep 2013

Women are 25% less likely to die post TAVI than men, says doctor

Dr Sherif said: "Earlier studies on the impact of gender on outcome after transcatheter aortic valve implantation (TAVI) have had conflicting results. A Canadian study reported in 641 consecutive patients that female sex is associated with a better long-term and short-term survival after TAVI.1 An Italian study of 305 high risk patients found no gender differences in composite safety and efficacy endpoints at 30 days and one year after TAVI."2

2 Sep 2013

Aortic stenosis doubles in patients with family history of the condition

Aortic stenosis is the most common heart valve disease in the elderly. It is associated with congenital bicuspid aortic valve and previous rheumatic heart disease, but is also often caused by calcification of a normal valve. Calcification of a normal valve may be associated with atherosclerotic changes in the portion of the aorta closest to the valve.

2 Sep 2013

Study may allow more patients to benefit from transcatheter aortic valve replacement

The Society of Thoracic Surgeons (STS) has launched an investigational study with the American College of Cardiology (ACC) that may allow more patients to benefit from transcatheter aortic valve replacement (TAVR), a minimally invasive procedure that delivers a replacement heart valve via a catheter.

18 Jul 2013

New treatment option for patients with aortic stenosis

Robert Stoler, MD, FACC, FSCAI, director of the Cardiac Catheterization Lab at Baylor Heart and Vascular Hospital and co-medical director, Division of Cardiology, is leading Baylor's participation in an exciting clinical trial to research a new treatment option for AS patients.

From Medtronic 21 Jun 2013

New HELIO dock system acts as anchor to stabilise SAPIEN XT valve for aortic insufficiency patients

A new investigational device - the Helio System (TF-FA) - being developed for use with the Sapien XT Transcatheter Heart Valve was successfully deployed in all four patients in a small, first-in-human feasibility study of its use in high-risk aortic insufficiency reported at EuroPCR 2013.

27 May 2013

Transcatheter aortic valve implantation is safe and effective in Asian patients

Transcatheter aortic valve implantation (TAVI) is effective and safe in Asian patients, according to early experience based on first results from a multicentre Asian registry reported at EuroPCR 2013.

27 May 2013

REPRISE II trial: Lotus Valve System meets primary endpoint in severe aortic valve disease patients

Boston Scientific Corporation reports positive results from a pre-specified analysis of the first 60 patients enrolled in the REPRISE II trial evaluating the performance and safety of the Lotus™ Valve System in symptomatic patients with severe aortic valve disease considered at high risk for surgical valve replacement.

23 May 2013

Loyola University Medical Center physicians deploy aortic valve through patient's abdomen

In a first-of-its-kind procedure in the United States, Loyola University Medical Center physicians have deployed an aortic valve by going through a patient's abdomen.

18 Apr 2013

Study: MDCT helps measure annular size in aortic stenosis patients in better way

MDCT is a better way to measure annular size in patients with aortic stenosis who are candidates for transcatheter aortic valve implantation than two dimensional echocardiography, a new study indicates.

15 Apr 2013

Society of Thoracic Surgeons releases aortic valve, ascending aorta clinical practice guidelines

The Society of Thoracic Surgeons has released a set of clinical practice guidelines to address major advances in the evaluation and management of patients with aortic valve disease.

1 Apr 2013

Catheter-delivered aortic valve durable at three years

All-cause and cardiovascular mortality were similar for transaortic valve replacement compared to open-heart surgery in high-risk older patients at three years with no increased risk of stroke after 30 days, according to results from the PARTNER study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

13 Mar 2013

New Sapien XT aortic valve reduces rate of death and strokes

The new Sapien XT aortic valve showed a non-significantly lower rate of death and strokes at 30 days than the original model, and both valves demonstrated notably better short-term outcomes than seen with the Sapien system in PARTNER I, according to the first results from the PARTNER II study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

FDA grants IDE approval to STS and ACC to study alternative access approaches for TAVR

The Society of Thoracic Surgeons (STS) and the American College of Cardiology (ACC) have received a unique investigational device exemption (IDE) from the U.S. Food and Drug Administration (FDA) to study "alternative access" approaches for transcatheter aortic valve replacement (TAVR) using the STS/ACC TVT Registry.

14 Feb 2013

Lipid associated variant linked to aortic stenosis, valve disorders

People who carry a lipoprotein(a) gene variant are at increased risk for aortic valve calcification and aortic stenosis, suggest study findings.

11 Feb 2013