Aspirin News and Research

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Aspirin also known as acetylsalicylic acid is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin also has an antiplatelet, or "anti-clotting", effect and is used in long-term, low doses to prevent heart attacks, strokes and blood clot formation in people at high risk for developing blood clots. It has also been established that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue.

Fatty acid-derived bioactive molecule helps improve heart function after heart attack in mice

Heart attacks provoke an acute immune response. Leukocytes rush to the heart muscle to remove dead cells and begin building scar tissue. This is followed by a second immune response, the resolving phase that allows healing.

7 Sep 2017

Antidepressants used for chronic pain relief come with significant side effects

Chronic pain negatively impacts a person's quality of life. Often, over the counter pain medication, such as ibuprofen or aspirin, are ineffective in alleviating chronic pain. In these instances, a surprising choice is often a drug used to treat an entirely different condition - depression.

5 Sep 2017

Mild pain killer blocks action of key protein required for hearing

A Rice University study has found that the aspirin-like drug diflunisal blocks the action of prestin, a key protein that is required for hearing.

5 Sep 2017

Long-term use of anti-inflammatory drugs can slow muscle growth in young people

The long-term use of over-the-counter (OTC) anti-inflammatory drugs can inhibit muscle growth in young, healthy individuals engaging in weight training, according to a new study from Karolinska Institutet, reporting on the effects of ibuprofen on the skeletal muscles and published in Acta Physiologica.

28 Aug 2017

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

Drug combination superior in preventing further heart complications in people with vascular disease

A major international study has found that the combination of two drugs - rivaroxaban and aspirin -- is superior to aspirin alone in preventing further heart complications in people with vascular disease.

28 Aug 2017

Two anticlotting medicines better at reducing bleeding risk than triple therapy

Using just two anticlotting medicines for patients who have atrial fibrillation and have had a stent placed in a heart artery is safer than using the current standard treatment of three medications, according to a new study presented by Brigham and Women's Hospital cardiologist Christopher Cannon, MD, at the European Society of Cardiology and published simultaneously in The New England Journal of Medicine.

28 Aug 2017

Gut-on-chips can predict effectiveness of candidate drugs

Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.

22 Aug 2017

Study shows role of cholesterol crystals during heart attack

A new Michigan State University study on 240 emergency room patients shows just how much of a role a person's cholesterol plays, when in a crystallized state, during a heart attack.

18 Aug 2017

Specific drug regimen taken prior to surgery reduces risk of cancer recurrence, study finds

Most cancer-related deaths are the result of post-surgical metastatic recurrence. In metastasis, cells of primary tumors travel to other parts of the body, where they often proliferate into inoperable, ultimately fatal growths.

7 Aug 2017

Researchers develop new scoring method to predict bleeding risk after stroke

A new scoring method may help predict who is at high risk of serious bleeding after a stroke, according to a study published in the August 2, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

2 Aug 2017

Researchers find new way to protect stem cells from inflammation during wound repair

Scientists have found a new way to protect stem cells from harsh inflammation during wound repair. In a study recently published in the journal Cytotherapy, researchers in India discovered that treating mice with a common anti-inflammatory drug called celecoxib promoted stem cell survival and healing when they injected the cells into wounds.

20 Jul 2017

Study finds inappropriate prescription of antiplatelet drugs in older patients

A study has found that antiplatelet drugs, such as aspirin, are often inappropriately prescribed in acutely hospitalized older people.

19 Jul 2017

Erectile dysfunction drug may be used to coat stents in future heart surgeries

Coating stents with an erectile dysfunction drug may be the way forwards in treating stent patients, say researchers.

12 Jul 2017

Novel small molecule tracer for PET imaging spots blood clots

Blood clots in veins and arteries can lead to heart attack, stroke, and pulmonary embolism, which are major causes of mortality.

6 Jul 2017

Study finds link between new opioid use and increased risk of cardiac death in older adults with COPD

Older adults with chronic obstructive pulmonary disorder who recently started using opioids have an increased risk of coronary artery disease-related death compared to non-opioid users, researchers at St. Michael's Hospital have found.

29 Jun 2017

New web calculator could reliably predict chances of survival for bowel cancer patients

"How long do I have, doctor?" For many cancer patients, following the initial shock of their diagnosis, thoughts quickly turn to estimating how much precious time they have left with family and friends or whether certain treatments could prolong their life.

16 Jun 2017

NSAIDs linked to longer survival for certain colorectal cancer patients

Among long-term colorectal cancer survivors, use of nonsteroidal anti-inflammatory drugs, or NSAIDs, is associated with about a 25 percent reduction in all-cause mortality, according to new research from Fred Hutchinson Cancer Research Center published online in the Journal of Clinical Oncology.

16 Jun 2017

New position paper recommends sex-specific cardiovascular drug dosages for better treatment

Sex-specific cardiovascular drug dosages are needed to reduce adverse reactions in women, according to a position paper from the European Society of Cardiology published today in the June issue of European Heart Journal - Cardiovascular Pharmacotherapy.

15 Jun 2017

Regular intake of Aspirin in elderly could mean higher than previously thought risk of bleeding says new study

New research shows that the use the antiplatelet drug Aspirin over long term among elderly is fraught with more risks than earlier believed.

14 Jun 2017

Aspirin News and Research

Fatty acid-derived bioactive molecule helps improve heart function after heart attack in mice

Antidepressants used for chronic pain relief come with significant side effects

Mild pain killer blocks action of key protein required for hearing

Long-term use of anti-inflammatory drugs can slow muscle growth in young people

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Drug combination superior in preventing further heart complications in people with vascular disease

Two anticlotting medicines better at reducing bleeding risk than triple therapy

Gut-on-chips can predict effectiveness of candidate drugs

Study shows role of cholesterol crystals during heart attack

Specific drug regimen taken prior to surgery reduces risk of cancer recurrence, study finds

Researchers develop new scoring method to predict bleeding risk after stroke

Researchers find new way to protect stem cells from inflammation during wound repair

Study finds inappropriate prescription of antiplatelet drugs in older patients

Erectile dysfunction drug may be used to coat stents in future heart surgeries

Novel small molecule tracer for PET imaging spots blood clots

Study finds link between new opioid use and increased risk of cardiac death in older adults with COPD

New web calculator could reliably predict chances of survival for bowel cancer patients

NSAIDs linked to longer survival for certain colorectal cancer patients

New position paper recommends sex-specific cardiovascular drug dosages for better treatment

Regular intake of Aspirin in elderly could mean higher than previously thought risk of bleeding says new study

Could smart vital sign monitoring provide an early warning system for hospitals?

Neurohistology: how whole slide scanning impacts workflow

Analytical Science in Precision Medicine

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