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Mast cell receptor linked to alcohol withdrawal-associated headaches

Researchers investigate the role of the mast-cell-specific receptor Mas-related G-protein-coupled receptor B2 (MrgprB2) in alcohol-withdrawal-induced headaches.

2 Nov 2023

Highly sensitive blood test shows promise for early detection of common deadly cancers

Most cancers become deadly by keeping a low profile, causing no symptoms until they're too advanced to treat. Ovarian and gastroesophageal cancers are among the most notorious for this sly disease progression, often leading to late-stage diagnoses.

1 Nov 2023

How to optimize nuclei extraction & counting for single cell sequencing

In this interview, News Medical talks to DeNovix about the best way to prepare nuclei samples before single cell sequencing workflows and optimize nuclei extraction.

From DeNovix Inc. 1 Nov 2023

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

Researchers aimed to identify dependable protein biomarkers for multiple sclerosis (MS).

1 Nov 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

The role of anti-SARS-CoV-2 antibody levels on COVID-19 outcomes in patients with T2D.

30 Oct 2023

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

Canadian researchers develop a cell-free DNA-based multimodal assay for early cancer detection in patients with Li-Fraumeni Syndrome, a high-cancer-risk condition. The assay outperforms conventional methods, promising more sensitive and less invasive cancer surveillance.

29 Oct 2023

IU researchers play key roles in national consortium to study the use of Alzheimer's disease biomarkers

Researchers at Indiana University School of Medicine will play key roles in a national consortium led by Wake Forest University School of Medicine to study the use, interpretation and implementation of biomarkers to diagnose Alzheimer's disease.

27 Oct 2023

Low-cost anti-inflammatory hydrogel could help treat chronic skin lesions in people with diabetes

Researchers in São Paulo state, Brazil, have developed a low-cost anti-inflammatory hydrogel that in future could help treat chronic skin lesions such as those often seen in people with diabetes.

27 Oct 2023

Beckman Coulter Life Sciences and 10x Genomics partner to enable single cell workflow automation

Beckman Coulter Life Sciences and 10x Genomics, Inc. today announced a new partnership to expand automation solutions for single cell assay workflows.

From Beckman Coulter Life Sciences 27 Oct 2023

New Sartorius Digital Handbook brings the power of advanced flow cytometry to every scientist

Sartorius, an industry-leading innovator of advanced instruments for cell analysis has released its first Advanced Flow Cytometry Handbook as a comprehensive digital guide to assays and workflows on the iQue® Advanced High Throughput Flow Cytometry Platform.

From Sartorius 26 Oct 2023

Sphere Fluidics' Expansion and Vision

In this interview, Rob Trainor, the Vice President of Operations at Sphere Fluidics, sits down for an insightful conversation detailing the completion of Sphere Fluidics' new state-of-the-art facilities and the strategic decisions behind their office move and rebranding.

From Sphere Fluidics 25 Oct 2023

Utilizing Biomarkers in Cancer Prevention, Diagnosis, and Treatment

In this interview, Grace Liu from Sino Biological discusses the crucial role of biomarkers in cancer prevention and diagnosis and how they can help guide treatment decisions.

From Sino Biological Inc. 24 Oct 2023

Intranasal vaccination: A potent one-time solution for comprehensive COVID-19 immunity

A single-dose intranasal vaccine effectively induces robust immune responses.

24 Oct 2023

Hormone levels tied to metabolic health in obesity

Researchers investigate the relationship between obesity types and serum leptin (LEP) and adiponectin (ADP) levels, shedding light on metabolic differences in various obesity phenotypes. Their findings highlight correlations between adipokines, glucose utilization, lipid metabolism, and obesity-related metabolic disorders.

22 Oct 2023

How chromatin compartmentalization affects DNA damage response

Researchers uncover novel insights into how chromatin compartmentalization influences the DNA damage response (DDR) after double-stranded breaks (DSBs), shedding light on the mechanisms behind genomic integrity maintenance and the risk of translocations. Their findings reveal the importance of chromosomal design in DNA repair and the potential implications for genome stability and cancer translocations.

22 Oct 2023

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

Johns Hopkins researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive.

20 Oct 2023

Canine transmission models provide insights into the neurological impacts of COVID-19 on human brains

The histopathologic alteration caused by SARS‑CoV‑2 on mammalian neurological systems.

20 Oct 2023

The beneficial effects of regular physical activity on the cardiovascular profile in the elderly

The effect of regular physical activity (PA) on the microcirculatory functions and plasma antioxidant capacity in older athletes.

20 Oct 2023

Assay News and Research

Mast cell receptor linked to alcohol withdrawal-associated headaches

Highly sensitive blood test shows promise for early detection of common deadly cancers

How to optimize nuclei extraction & counting for single cell sequencing

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

How one gene shakes up our understanding of male infertility

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

IU researchers play key roles in national consortium to study the use of Alzheimer's disease biomarkers

Low-cost anti-inflammatory hydrogel could help treat chronic skin lesions in people with diabetes

Beckman Coulter Life Sciences and 10x Genomics partner to enable single cell workflow automation

New Sartorius Digital Handbook brings the power of advanced flow cytometry to every scientist

Sphere Fluidics' Expansion and Vision

Utilizing Biomarkers in Cancer Prevention, Diagnosis, and Treatment

Intranasal vaccination: A potent one-time solution for comprehensive COVID-19 immunity

Hormone levels tied to metabolic health in obesity

How chromatin compartmentalization affects DNA damage response

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

Canine transmission models provide insights into the neurological impacts of COVID-19 on human brains

The beneficial effects of regular physical activity on the cardiovascular profile in the elderly

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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