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Study on papillary thyroid carcinoma to be presented at 84th Annual Meeting of the ATA

The prevalence of papillary thyroid carcinoma (PTC), the most common type of thyroid cancer, is increasing rapidly. New research to determine the impact of radioactive iodine (RAI) therapy on survival in PTC, describing a novel blood test able to detect circulating BRAFV600E-positive tumor DNA, and identifying a long non-coding RNA specifically associated with the thyroid that is down-regulated in PTC compared to normal thyroid tissue in patient-derived clinical specimens and cell cultures will be featured in oral presentations delivered at the 84th Annual Meeting of the American Thyroid Association, October 29-November 2, 2014, in Coronado, California.

30 Oct 2014

BloodCenter of Wisconsin announces availability of cancer mutation HemeOnc Panel

BloodCenter of Wisconsin's Diagnostic Laboratories today announced the availability of a comprehensive cancer mutation HemeOnc Panel using next generation sequencing (NGS) technology. The NGS panel developed by BloodCenter of Wisconsin is designed to detect variants in 30 genes that are either prognostic or diagnostic for 10 different myeloid hematologic malignancies.

30 Oct 2014

Influential colleagues convince doctors to try new therapies

Doctors are more likely to try a new therapy when they are persuaded to do so by an influential colleague, reports a new Northwestern University study whose findings on adopting innovations also have relevance for business, education and research.

28 Oct 2014

BioTek awarded US Patent for automated ultrasonic blockage detection and cleaning in microplate washers

BioTek has been awarded U.S. Patent 8,858,718, covering the use of ultrasonic devices to check for clogged manifold tubes and to clean the manifold tubes of a microplate washer automatically. The two features are known as Verify™ and Ultrasonic Advantage™ and are available in BioTek’s 405 family of microplate washers.

28 Oct 2014

Pulmocide uses INTEGRA's VIAFLO Assist pipetting assistant to improve screening of novel compounds

INTEGRA reports on how respiratory drug discovery and development specialists - Pulmocide Ltd. (London, UK) are using a VIAFLO Assist pipetting assistant to enhance the productivity and reproducibility of their screening of novel compounds in a range of biological assays.

From INTEGRA Biosciences 28 Oct 2014

RPC1063 drug candidate has potential to improve treatment for ulcerative colitis patients

Positive new clinical data were released today on a drug candidate for ulcerative colitis that was first discovered and synthesized at The Scripps Research Institute.

28 Oct 2014

New findings could help develop antibiotics with lower risk of resistance

Scientists have used computer simulations to show how bacteria are able to destroy antibiotics – a breakthrough which will help develop drugs which can effectively tackle infections in the future.

20 Oct 2014

Leading UK supplier uses INTEGRA’s VIAFLO II, VIAFLO ASSIST to improve assay consistency

A leading UK supplier of early-stage drug discovery and development process services has improved the consistency and efficiency of its assays using VIAFLO II pipettes and a VIAFLO ASSIST from INTEGRA. By mounting a VIAFLO II electronic pipette on the VIAFLO ASSIST, the pipette’s protocols can be carried out fully automatically.

From INTEGRA Biosciences 15 Oct 2014

Molecular diagnostics and blood screening systems: an interview with Dr Bos and Dr Koppelman

Screening blood donations and molecular diagnostics for patients started in the nineties. At the beginning, the level of automation in molecular diagnostic testing was limited; most of the work had to be done manually.

12 Oct 2014

RNA molecules in tissue, urine samples can detect prostate cancer

Researchers at Sanford-Burnham Medical Research Institute have identified a set of RNA molecules that are detectable in tissue samples and urine of prostate cancer patients but not in normal healthy individuals.

10 Oct 2014

EPFL scientists discover two molecules that could overcome multidrug resistance in tuberculosis

Using a high-throughput screening assay, EPFL scientists have discovered two small molecules that could overcome the multidrug resistance of the bacterium that causes tuberculosis.

9 Oct 2014

TGen, NAU awarded patent for genomics-based test to detect H1N1 pandemic flu strain

The federal government has awarded a patent to the Translational Genomics Research Institute and Northern Arizona University for a test that can detect — and assist in the treatment of — the H1N1 pandemic flu strain.

9 Oct 2014

Study: H7N9 flu vaccine combined with adjuvant is essential to promote protective immune response

A large, NIH-sponsored clinical trial of an experimental H7N9 avian influenza vaccine found an immune response that was believed to be protective in 59 percent of study participants who received two injections of the inactivated vaccine at the lowest dosage tested when mixed with an adjuvant – a component that boosts the body's immune response and enhances the effectiveness of inactivated influenza vaccines.

8 Oct 2014

Absorption Systems supports Pediatric Praziquantel Consortium led by Merck KGaA

Absorption Systems, a leader in preclinical contract testing of drugs, biologics, and medical devices, announces that it has been subcontracted by the German pharmaceutical company Merck KGaA to work on a new pediatric formulation of praziquantel.

7 Oct 2014

NCI awards $1.4M grant to Advanced Cell Diagnostics to develop diagnostic test for B-cell NHLs

Advanced Cell Diagnostics, Inc. (ACD), a global technology and market leader in in situ nucleic acid detection for life science research and clinical diagnostics, has been awarded a two-year, $1.4 million grant from National Cancer Institute (NCI) under its SBIR Phase II Program.

From Advanced Cell Diagnostics 7 Oct 2014

MyCartis announces launch of digital multiplex biomarker analysis platform

MyCartis today announced the launch of Evalution, a multiplex biomarker analysis platform for the life sciences research market.

7 Oct 2014

NanoString, BWH partner to translate genomic biomarker discoveries into clinical cancer diagnostics

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced that it has signed a multi-year, multi-investigator research collaboration with Harvard-affiliated Brigham and Women's Hospital to accelerate the translation of genomic biomarker discoveries into clinical cancer diagnostics.

From NanoString Technologies 7 Oct 2014

UPM researchers find way to enhance detection of rotavirus

Researchers at the Universidad Politécnica de Madrid have found a way to enhance detection capacity of small concentrations of rotavirus. All this thanks to a new way to assess the biosensing response applied to an interferometric device.

3 Oct 2014

COMPAC-50 enables simultaneous electrophoresis of up to 50 COMET Assay slides

Developed in collaboration with the Oxidative Stress Group at the University of Leicester (Leicester, UK), the unique design of the COMPAC-50 enables simultaneous electrophoresis of up to 50 COMET Assay slides saving considerable lab space and reducing slide handling time by up to two-thirds when compared to previous standard methods. This would equate to a significant time-saving of up to 90% when handling 50 COMET Assay slides.

From Cleaver Scientific Ltd 3 Oct 2014

Metamark expands prostate cancer test services to include PROGENSAPCA3 assay

Metamark announced today the expansion of its prostate cancer test services to now include the PROGENSA® PCA3 assay, a urine-based test that can help confirm negative prostate biopsies, and ERG, a companion test to the company's existing PTEN assay.

1 Oct 2014

Assay News and Research

Study on papillary thyroid carcinoma to be presented at 84th Annual Meeting of the ATA

BloodCenter of Wisconsin announces availability of cancer mutation HemeOnc Panel

Influential colleagues convince doctors to try new therapies

BioTek awarded US Patent for automated ultrasonic blockage detection and cleaning in microplate washers

Pulmocide uses INTEGRA's VIAFLO Assist pipetting assistant to improve screening of novel compounds

RPC1063 drug candidate has potential to improve treatment for ulcerative colitis patients

New findings could help develop antibiotics with lower risk of resistance

Leading UK supplier uses INTEGRA’s VIAFLO II, VIAFLO ASSIST to improve assay consistency

Molecular diagnostics and blood screening systems: an interview with Dr Bos and Dr Koppelman

RNA molecules in tissue, urine samples can detect prostate cancer

EPFL scientists discover two molecules that could overcome multidrug resistance in tuberculosis

TGen, NAU awarded patent for genomics-based test to detect H1N1 pandemic flu strain

Study: H7N9 flu vaccine combined with adjuvant is essential to promote protective immune response

Absorption Systems supports Pediatric Praziquantel Consortium led by Merck KGaA

NCI awards $1.4M grant to Advanced Cell Diagnostics to develop diagnostic test for B-cell NHLs

MyCartis announces launch of digital multiplex biomarker analysis platform

NanoString, BWH partner to translate genomic biomarker discoveries into clinical cancer diagnostics

UPM researchers find way to enhance detection of rotavirus

COMPAC-50 enables simultaneous electrophoresis of up to 50 COMET Assay slides

Metamark expands prostate cancer test services to include PROGENSAPCA3 assay

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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