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Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Amyotrophic lateral sclerosis is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS.

16 Apr 2018

Biomarker panel can guide future therapeutic decisions for glioma patients

In an article published April 10th in the journal Cell Reports, researchers at the University of São Paulo describe a biomarker panel that could tell physicians which patients diagnosed with glioma, a type of brain cancer, will tend to progress to a more aggressive form of the disease in the event of relapse.

10 Apr 2018

Novel method enables researchers to see interaction of star-shaped brain cells in real time

An advance by UCLA neuroscientists could lead to a better understanding of astrocytes, a star-shaped brain cell believed to play a key role in neurological disorders like Lou Gehrig's, Alzheimer's and Huntington's disease.

4 Apr 2018

Adult-onset degenerative disease mechanism begins much earlier than previously thought

The disease mechanism for adult-onset progressive degenerative diseases begins much earlier than previously thought, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

30 Mar 2018

New gene therapy may help the brain to heal following stroke and other injuries

Researchers have discovered a genetic trigger that may improve the brain’s ability to heal in conditions such as stroke, concussion and spinal cord injury.

28 Mar 2018

Study uncovers genetic trigger that may help the brain to recover from stroke, other injuries

Scientists have found a genetic trigger that may improve the brain's ability to heal from a range of debilitating conditions, from strokes to concussions and spinal cord injuries.

27 Mar 2018

SLU researchers turn off excruciating chemo pain in animal model

In a recent paper published in the journal Pain, Saint Louis University researchers describe their success in an animal model in turning off the excruciating pain that often accompanies a colorectal cancer drug.

26 Mar 2018

Findings reveal dramatic landscape of genetic changes in the brain in response to visual stimulation

"Nature and nurture is a convenient jingle of words, for it separates under two distinct heads the innumerable elements of which personality is composed.

9 Feb 2018

Research funded by NIH grant aims to discover crucial role of 'invisible' cells

Neurons are the star of the show in brain science, but they don't work alone to process information. In new research funded by a $1.9 million grant from the National Institutes of Health, a team at MIT's Picower Institute for Learning and Memory aims to discover the likely crucial role of the supporting cast member with a stellar-sounding name: the astrocyte.

9 Feb 2018

Star-shaped brain cells may help control rhythm of breathing, NIH study suggests

Traditionally, scientists thought that star-shaped brain cells called astrocytes were steady, quiet supporters of their talkative, wire-like neighbors, called neurons. Now, an NIH study suggests that astrocytes may also have their say.

8 Feb 2018

MILabs completes installation of latest VECTor5CT system at University of Copenhagen

MILabs announced today that it has successfully completed the installation of its top-of-the-line multimodality PET-SPECT-UHR CT in the laboratory of Prof. Maiken Nedergaard, M.D, D.M.Sci. – Center for Translational Neuroscience, Division of Glial Disease and Therapeutics.

6 Feb 2018

Low dose alcohol everyday might actually "clean" the brain

A new study in mice has suggests that a couple of glasses of wine may actually “clean” the brain and not only clear the mind at the end of a long day. The study was published in the latest issue of the journal Scientific Reports.

5 Feb 2018

Low levels of alcohol helps the brain clear away toxins, study shows

While a couple of glasses of wine can help clear the mind after a busy day, new research shows that it may actually help clean the mind as well.

2 Feb 2018

New study sheds light on important protein involved in memory formation

A team of researchers have made important discoveries about a protein called AKT that is key to the formation of new memories.

29 Jan 2018

Discovery may advance stem cell therapies, gene-targeting treatments for neurological diseases

New research from Sanford Burnham Prebys Medical Discovery Institute is among the first to describe how an mRNA modification impacts the life of neural stem cells.

24 Jan 2018

Researchers find more precise, neuroprotective approach to fix MS-damaged nerves

Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases.

26 Dec 2017

3D mini brains put researchers on a fast track to repair the nervous system

The Houston Methodist Research Institute is making mini brains from human stem cells that put researchers on a fast track to repair the nervous system after injury or disease of the brain and spinal cord.

8 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

MUSC researchers develop ex vivo model of pressure-induced cellular injury in the brain

Hundreds of thousands of patients from newborns to the elderly are forced to grapple with the devastation of brain injury each year, and unlike many diseases where certain demographics are protected, brain injury can happen to anyone, anytime and anywhere.

4 Dec 2017

Scientists develop new method to study Creutzfeldt-Jakob disease in the lab

Scientists have developed a new system to study Creutzfeldt-Jakob disease in the laboratory, paving the way for research to find treatments for the fatal brain disorder.

20 Nov 2017