Atorvastatin News and Research

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Different statin drugs exert different effects on COVID-19 patients

We've all recently gotten a crash-course in drug repurposing, thanks to near-daily news reports about efforts to identify existing medicines that could help treat COVID-19 in the early phase of the pandemic.

9 May 2023

Investigating treat-to-target low-density lipoprotein-cholesterol versus high-intensity statins for coronary artery disease

In a recent study published in JAMA, researchers investigated whether treat-to-target (TTT) low-density lipoprotein-cholesterol (LDL-C) therapy was inferior to administering statins of high intensity for clinical outcomes in the long term among coronary artery disease (CAD) patients.

8 Mar 2023

Mark Cuban has been taking on the drug industry. But which one?

When billionaire Mark Cuban announced his attack on the pharmaceutical industry and its high-priced drugs in January 2021, it was met with cheers.

17 Feb 2023

Oral anticoagulant does not help patients recovering from moderate and severe COVID-19

A drug used to reduce the risk of blood clots does not help patients recovering from moderate and severe COVID-19, despite this approach being offered to patients, a UK-wide trial, led by Addenbrooke's Hospital and the University of Cambridge has found.

28 Nov 2022

Exploring the muscle symptoms associated with statin therapy

In a new study, investigators explored the influences of statin treatment on muscle symptoms.

31 Aug 2022

Three-drug medication effective in preventing recurrent cardiovascular events after a heart attack

A three-drug medication known as a "polypill," developed by the Spanish National Center for Cardiovascular Research (CNIC) and Ferrer, is effective in preventing secondary adverse cardiovascular events in people who have previously had a heart attack, reducing cardiovascular mortality by 33 percent in this patient population.

26 Aug 2022

What is the optimal LDL cholesterol level for patients with cardiovascular diseases?

In a new study, the effectiveness of low low-density lipoprotein cholesterol levels in reducing the risk of atherosclerotic vascular events was explored.

6 Jul 2022

Study predicts that different statins exhibit divergent effects on host response to SARS-CoV-2 infection

A new study explores the possibility that different statins may exhibit different effects within the host and may differ in their outcomes while treating COVID-19 patients.

18 Apr 2022

New smartphone app can calculate users’ genetic risk for coronary artery disease

A Scripps Research team developed a smartphone app that can calculate users' genetic risk for coronary artery disease (CAD)-; and found that users at high risk sought out appropriate medication after using the app.

14 Mar 2022

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

Researchers have screened several compounds that could show the ability to inhibit SARS-CoV-2.

10 Dec 2021

Commonly prescribed medications can make the flu virus more or less active

Although the influenza virus varies a lot from year to year, the flu usually contributes to approximately 1000 deaths a year in Norway.

19 Oct 2021

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study.

20 Sep 2021

Study finds a significant link between statins and survival rates of triple-negative breast cancer patients

A study led by researchers from The University of Texas MD Anderson Cancer Center found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes for this aggressive disease.

3 Aug 2021

Study: Benefit-to-harm balance of statins for primary prevention of heart disease is favorable

Statins are associated with a small increased risk of side effects in patients without a history of heart disease, but these effects are mild compared with the potential benefits of treatment in preventing major cardiovascular events, say researchers in The BMJ today.

14 Jul 2021

Statins improve 28-day mortality in hospitalized COVID-19 patients

Now, researchers at Harvard Medical School showed that statin use reduced 28-day mortality in patients hospitalized with COVID-19. Both the new initiation of statins and continuing statin therapy reduced the risk of mortality.

8 Apr 2021

Scientists develop a simple method to make drug precursor

Save your silver! It's better used for jewelry than as a catalyst for drugs. Rice University scientists have developed a greatly simplified method to make fluoroketones, precursors for drug design and manufacture that typically require a silver catalyst.

27 Feb 2021

New combination treatment approach improves overall survival in mice with glioblastoma

In a study of mice, researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new approach that combines an anti-psychotic drug, a statin used to lower high cholesterol levels, and radiation to improve the overall survival in mice with glioblastoma.

9 Feb 2021

Study provides reassurance that patients and providers can use pharmacogenetic testing

A person's genetic make-up can influence whether they might experience side effects from certain medications.

3 Dec 2020

Selective statins may reduce SARS-CoV-2 cell entry and inhibit infection

Statins are a class of drugs often used to control high cholesterol levels in obesity. Now, a study published on the preprint server medRxiv* in July 2020 suggests that statins do not aggravate the risk of COVID-19 infection and may have a small beneficial effect in some cases.

16 Jul 2020

Statin therapy linked to lower death rate in hospitalized patients with COVID-19

The use of cholesterol-lowering drugs called statins is associated with a lower death rate and a lower incidence of mechanical ventilation in patients hospitalized with Coronavirus disease 2019 (COVID-19), researchers report June 24 in Cell Metabolism.

24 Jun 2020