Autoantibodies News and Research

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Antibodies could cause arthritic pain

Antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis, researchers from Karolinska Institutet in Sweden report.

13 Jun 2019

Study finds potential treatment for patients with Complex Regional Pain Syndrome

A study, published today in PNAS, has found a potential treatment for patients with Complex Regional Pain Syndrome.

11 Jun 2019

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

A drug that targets the immune system can delay the onset of type 1 diabetes an average of two years in children and adults at high risk, according to findings from TrialNet's Teplizumab (anti-CD3) Prevention Study published in the New England Journal of Medicine.

10 Jun 2019

Increasing early beta-cell proliferation could halt development of type 1 diabetes

Many in-development cures for type 1 diabetes have understandably focused on tackling the autoimmune aspect of the disease before figuring out a way to replace the destroyed beta cells. But what if focusing on the beta cells first could prevent their destruction altogether?

7 May 2019

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Biomolecular researcher Navin Varadarajan has published in Arthritis & Rheumatology journal a first-of-its-kind study - a comprehensive profile of B cells in rheumatoid arthritis.

12 Apr 2019

MUSC study provides evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

Human immunodeficiency virus, or HIV, attacks the immune system, making affected individuals more susceptible to infections. When patients with HIV are treated with antiretroviral therapy, their immune system can recover, but some of them produce self-destructive proteins, or autoantibodies.

2 Apr 2019

Better regulation of the immune system may help manage preeclampsia

Boosting the body's levels of interleukin-4 (IL-4)--an immune system protein that controls inflammation--may help manage the pregnancy complication preeclampsia, according to a new rodent study.

7 Mar 2019

Researchers reveal promising biomarker for vascular disease relapse

Researchers at Okayama University report in the journal Arthritis & Rheumatology that monitoring a particular antigen can be used for predicting relapse of the vascular disease AAV.

28 Feb 2019

New system for early detection of lupus developed

Autoimmune diseases, such as systemic lupus erythematosus or rheumatoid arthritis, are difficult to diagnose, specially in early stages. Specifically, in the case of lupus, specific antibodies aimed at antigens located in the nucleus of cells appear, including the anti-Ro/SSA.

1 Feb 2019

OU researcher and collaborators are developing new strategies for early intervention of Lupus

A University of Oklahoma researcher, Si Wu, and collaborators from the Oklahoma Medical Research Foundation and Indiana University, are developing new strategies leading to diagnosis and early intervention of Lupus, an autoimmune disease that may affect up to 1.5 million Americans.

1 Feb 2019

Newly developed risk score more effective at identifying type 1 diabetes

A new way of screening babies and adults for future risk of type 1 diabetes will be much more effective at identifying the condition than current methods, new research has concluded.

18 Jan 2019

Study follows children into adolescence to more accurately assess type 1 diabetes risk

Scientists are narrowing in on checklists of both errant genes and the environmental factors that could trigger those genes to more accurately assess type 1 diabetes risk and help children and their families avoid it.

3 Jan 2019

FDA supports C-Path's Type 1 Diabetes Consortium to pursue biomarker qualification

Critical Path Institute (C-Path) announced today that its Type 1 Diabetes (T1D) Consortium has received a positive response to its Letter of Intent (LOI) from the U.S. Food and Drug Administration (FDA) detailing the FDA's decision to accept the consortium's Biomarker Initiative project into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program (BQP).

19 Dec 2018

Researchers highlight potential therapy for treating rare, deadly blood-clotting disorder

In proof-of-concept experiments, University of Alabama at Birmingham researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP.

24 Sep 2018

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Systemic sclerosis (SSc, also known as scleroderma), a connective tissue disorder of autoimmune etiology, is characterized by excessive fibrosis in the skin and various internal organs.

30 Aug 2018

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

A group of researchers at the University of São Paulo in Brazil used a DNA editing tool called CRISPR/Cas9 to manipulate on of the genes associated to the autoaggressive T lymphocytes responsible for inducing autoimmune diseases such as autoimmune polyglandular syndrome type 1 and type 1 diabetes.

2 Aug 2018

UH researchers awarded $2 million grant to unravel link between women and lupus

The chronic inflammatory disease systemic lupus erythematosus, is about nine times more common in women than men, and a University of Houston researcher now has the money to find out why.

1 Aug 2018

ECU researchers develop world’s first blood test that detects melanoma in its early stages

Edith Cowan University researchers have developed the world’s first blood test capable of detecting melanoma in its early stages, a breakthrough that will save thousands of lives, as well as millions of dollars for the health system.

20 Jul 2018

Melanoma could soon be detected using a blood test

West Australian researchers from Edith Cowan University have managed to develop a blood test that is capable of diagnosing melanomas before they can spread to other parts of the body. The study titled, “A diagnostic autoantibody signature for primary cutaneous melanoma,” was published in the latest issue of the journal Oncotarget.

18 Jul 2018

New mouse model could shed light on autism subtype

Researchers at the UC Davis MIND Institute have created a mouse model for maternal antibody- related (MAR) autism spectrum disorder that closely mimics the physiology and behaviors seen in people with this form of ASD.

29 Jun 2018