Autoantibodies News and Research

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Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty.

6 Dec 2016

Researchers identify new biomarker in spinal fluid and blood serum of patients with neurological disorder

Research from Mayo Clinic included in the November issue of JAMA Neurology identifies a new biomarker for brain and spinal cord inflammation, allowing for faster diagnosis and treatment of patients.

14 Nov 2016

New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research has shown how the immune system avoids attacking its own tissues with antibodies - whilst still maintaining a strong defence against invaders.

11 Nov 2016

Proteins in the blood of children can predict risk for incipient type 1 diabetes

Certain proteins in the blood of children can predict incipient type 1 diabetes, even before the first symptoms appear. A team of scientists at the Helmholtz Zentrum München, partners in the German Center for Diabetes Research, reported these findings in the 'Diabetologia' journal.

7 Nov 2016

Folinic acid treatment could help improve language and communication skills of children with ASD

Prescription doses of folinic acid, which is a reduced form of a B vitamin known as folate, could help improve the language and communication skills of children with autism spectrum disorder (ASD).

18 Oct 2016

New T cell subset may play vital role in development of type 1 diabetes

A study conducted at the University of Eastern Finland revealed that a recently described T cell subset may have a central role in the development of type 1 diabetes.

12 Oct 2016

New biomarker test helps detect autoimmune-induced neuropsychiatric disorders

A research team from the University of Oklahoma Health Sciences Center, led by Madeleine Cunningham, Ph.D., in conjunction with the National Institute of Mental Health, has developed the first-of-its-kind biomarker test to help detect autoimmune-induced neuropsychiatric disorders.

9 Sep 2016

Integration of multiple types of protein biomarkers improves ability to detect breast cancer

A first-time study published in PLOS ONE shows that a combined assessment of multiple types of protein biomarkers in the blood offers an important advancement for detecting early breast cancer.

11 Aug 2016

Neurologists identify cause of immune-mediated neuropathies

Würzburg neurologists have discovered an antibody that is involved in triggering certain forms of neuropathies. This discovery also allowed them to show a way to treat these diseases successfully.

3 Aug 2016

Researchers find different immunological profiles in HIV-infected individuals who produce bNAbs

People living with HIV who naturally produce broadly neutralizing antibodies (bNAbs) that may help suppress the virus have different immunological profiles than people who do not, researchers report.

30 Jul 2016

Immunotherapy-treated cancer patients may develop rheumatic disorders

Oncologists need to be aware of the potential for rheumatological diseases in patients with cancer following treatment with immune checkpoint inhibitors, say US investigators.

30 Jun 2016

Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

Mothers of children with autism and were diagnosed with metabolic conditions during pregnancy, particularly gestational and type 2 diabetes, were more likely to have anti-fetal brain autoantibodies in their blood compared to healthy women of children with autism.

20 Jun 2016

New blood test helps detect MCI stage of Alzheimer's disease

A research team, led by Dr. Robert Nagele from Rowan University School of Osteopathic Medicine and Durin Technologies, Inc., has announced the development of a blood test that leverages the body's immune response system to detect an early stage of Alzheimer's disease - referred to as the mild cognitive impairment (MCI) stage - with unparalleled accuracy.

8 Jun 2016

New hydrogel-based biochip may help in early diagnosis of bowel cancer

Researchers from the Moscow Institute of Physics and Technology, the Engelhardt Institute of Molecular Biology, the Institute of Bioorganic Chemistry and a number of other Russian research centers have developed a new method of diagnosing colorectal cancer.

27 May 2016

CSL362 antibody targets, depletes pDCs and other cells implicated in SLE

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems. Autoantibodies, which are produced by B cells, contribute to development of SLE.

6 May 2016

Duke scientists develop human-derived antibody that preferentially attacks cancer cells

A research team from Duke Health has developed an antibody from the body's own immune system that preferentially attacks cancer cells.

6 May 2016

Scientists uncover molecular identity of previously unknown Glima molecule in Type 1 diabetes

Scientists have solved a decades-old medical mystery by finally identifying a previously unknown molecule which is attacked by the immune system in people with Type 1 diabetes.

25 Apr 2016

Oxidized mitochondrial nucleoids released from neutrophils may contribute to SLE pathogenesis

Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus (SLE) patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response.

19 Apr 2016

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune disease, said researchers at Penn State College of Medicine.

12 Apr 2016

Rituximab shows second-line promise in autoimmune limbic encephalitis

Rituximab is an effective and well-tolerated second-line treatment for patients with autoimmune limbic encephalitis, suggests research.

7 Apr 2016