Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

LJI researchers uncover new drug target for severe asthma, lung fibrosis

If you've ever struggled to breathe, you've had a moment of hypoxia-;a lack of oxygen. Hypoxia can have long-term effects. In fact, doctors describe hypoxia as an "initial insult."

9 May 2022

Study identifies interleukin-6 as a potential target in refining cancer therapies

Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body's immune system to kill cancer.

9 May 2022

Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy

Researchers at The University of Texas MD Anderson Cancer Center have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6).

9 May 2022

Study finds 67% of individuals with long COVID are developing dysautonomia

In a recent study posted to the medRxiv* preprint server, researchers analyzed the traits of autonomic symptom burden in long coronavirus disease (COVID).

1 May 2022

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

A team led by the Institut de Neurociències at the Universitat Autònoma de Barcelona managed to reduce chronic inflammation associated with multiple sclerosis in mice thanks to the administration of a type of lipid that mediates inflammation.

27 Apr 2022

Cell division crucial for the success of macrophage infiltration

Researchers at ISTA discover a crucial process that enables immune cells to get to where they are needed. Study published in Science.

21 Apr 2022

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Despite the success of immunotherapy in helping many people with cancer, the majority of patients still do not respond to these treatments. There is need for continued research.

20 Apr 2022

CAR T-Cell Therapy: The Future of Cancer and HIV Treatment?

In this interview, News-Medical speaks to Professor Jun Huang about CAR T-cell therapy and its future as a potential treatment for cancer or HIV.

20 Apr 2022

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly.

18 Apr 2022

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

Researchers investigated the longevity and intensity of the SARS-CoV-2 vaccine immune response in patients suffering from immune-mediated inflammatory diseases.

15 Apr 2022

A comprehensive rule book for the design of safe and efficient therapeutic cells

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

15 Apr 2022

Dietary influences on long COVID in children

A new study discusses possible mechanisms of long COVID in children and how they might relate to their dietary intake of important vitamins and elements.

13 Apr 2022

Dysregulated retroelements associated with autoimmunity in COVID-19

Researchers investigate potential interactions between retro-elements shared between the human and coronavirus genomes.

12 Apr 2022

Alternative anti-HIV strategy generates promising results in a phase I clinical trial

vaccines against the virus, but unfortunately, HIV has numerous defense mechanisms that prevent a person's immune system from mounting an effective response following HIV vaccination.

11 Apr 2022

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

A variant of the CTLA-4 gene associated with autoimmune disease was found to be more frequent in non-small cell lung cancer (NSCLC) patients who experienced an exceptionally high response to anti-PD-1 immunotherapy and higher immune-related side effects than in a comparable cohort of lung cancer patients and healthy individuals, according to data presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

Most autoimmune diseases are easy to diagnose but hard to treat. A paper published today in Science proposes using your unique immune cell fingerprint to rapidly identify which treatments will work for your autoimmune disease.

7 Apr 2022

Researchers design RNA molecules for delivering therapies directly to beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 diabetes.

7 Apr 2022

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Critical Path Institute's Type 1 Diabetes Consortium (T1DC) today announced that the European Medicines Agency has issued a positive qualification opinion for pancreatic islet autoantibodies as enrichment biomarkers for type 1 diabetes (T1D) prevention trials.

5 Apr 2022

NYU Langone joins NIH-sponsored program as leading center to discover new targets for autoimmune, inflammatory diseases

NYU Langone Health is joining a new National Institutes of Health (NIH)-sponsored program called Accelerating Medicines Partnership Autoimmune and Immune-Mediated Diseases (AMP AIM) as a leading center to discover new targets for therapy in these diseases.

30 Mar 2022

Is SARS-CoV-2 a Superantigen?

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), scientists have been conducting extensive studies to understand various aspects of the virus. Researchers have stated that SARS-CoV-2 manifests several biological and clinical consequences of a superantigen

29 Mar 2022

Autoimmunity News and Research

Further Reading

LJI researchers uncover new drug target for severe asthma, lung fibrosis

Study identifies interleukin-6 as a potential target in refining cancer therapies

Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy

Study finds 67% of individuals with long COVID are developing dysautonomia

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

Cell division crucial for the success of macrophage infiltration

Newly discovered immune cell "soldier" could be a good target for immunotherapy

CAR T-Cell Therapy: The Future of Cancer and HIV Treatment?

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

A comprehensive rule book for the design of safe and efficient therapeutic cells

Dietary influences on long COVID in children

Dysregulated retroelements associated with autoimmunity in COVID-19

Alternative anti-HIV strategy generates promising results in a phase I clinical trial

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

Researchers design RNA molecules for delivering therapies directly to beta cells

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

NYU Langone joins NIH-sponsored program as leading center to discover new targets for autoimmune, inflammatory diseases

Is SARS-CoV-2 a Superantigen?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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