Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Lupus-linked genetic variants may boost antiviral immunity

Why do genetic variants that increase the risk of autoimmune disease remain so common in the population?

11 Sep 2026

COVID-19 linked to lower subsequent risk of type 1 diabetes

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) shows that people who have had COVID-19 have a lower, rather than higher, risk of subsequent development of type 1 diabetes (T1D).

8 Sep 2026

Researchers tested dozens of clues for long COVID. One finding stood out

A nationwide study of 218 people in the Faroe Islands examined clinical, neurological, and blood-based markers associated with persistent symptoms around six months after SARS-CoV-2 infection. Despite extensive testing, researchers found no convincing biomarker for long COVID, while a statistical association with lower INR remained within the normal clinical range and requires replication.

27 Aug 2026

Researchers uncover mechanism linking skin inflammation to body-wide allergies

Our bodies experience allergic reactions when the immune system mistakenly overreacts to harmless substances, known as allergens, such as pollen, dust, or certain foods.

6 Aug 2026

Too little or too much iodine may push immunity off balance

This narrative review finds that adequate iodine supports thyroid hormone signaling, leukocyte metabolism, antioxidant defenses, and antimicrobial activity in humans and domesticated mammals. Both deficiency and sustained excess may impair immunity or promote thyroid inflammation, but precise immune-specific intake thresholds remain uncertain.

27 Jul 2026

Mount Sinai establishes new autoimmunity center with $5 million gift

A $5 million gift from philanthropists Judith and Stewart Colton will establish a Colton Center for Autoimmunity within the Marc and Jennifer Lipschultz Precision Immunology Institute (PrIISM) at the Icahn School of Medicine at Mount Sinai.

21 Jul 2026

Dysregulation of immune regulator NF-κB drives major human diseases

NF‑κB controls genes involved in inflammation, immunity, cell survival, and proliferation. Triggered by cytokines (TNF‑α, IL‑1β), microbial products, or cellular stress, it translocates to the nucleus and induces pro‑inflammatory mediators.

13 Jul 2026

BCG vaccine may remodel the human brain's immune environment

New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine - which is delivered through the skin to prevent tuberculosis - may remodel the human brain's immune environment, offering a potential biological explanation for previously observed associations between BCG vaccination and lower Alzheimer's disease risk.

6 Jul 2026

Peacemaker immune cells offer new hope for restoring immune tolerance

'Peacemaker' immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a new paper in Frontiers in Science.

25 Jun 2026

Immunotherapy may help women with early ovarian insufficiency to conceive babies

A pilot study from Karolinska Institutet shows that immunotherapy may enable stimulation of egg maturation in women with autoimmune POI (premature ovarian insufficiency) – a condition that usually leads to infertility.

24 Jun 2026

Researchers uncover key mechanism driving chronic Sjögren disease

Sjögren disease, an autoimmune disease characterized by dry mouth and dry eyes, may reduce patients’ quality of life.

24 Jun 2026

MSU researchers develop tool to observe complex molecular choreography in real time

A lot of things need to go right on a molecular level for immune cells to launch an adaptive response to an infection.

23 Jun 2026

Aging immune cells may explain why autoimmunity rises later in life

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

21 Jun 2026

Study identifies an important driver of inflammatory bowel disease

Researchers at the Nuffield Department of Medicine, University of Oxford, together with Newcastle University's Translational and Clinical Research Institute and the Department of Immunology at Cambridge University Hospitals NHS Foundation Trust, have identified an important driver of inflammatory bowel disease (IBD).

10 Jun 2026

Philanthropic investment expands collaborative network for autoimmune research

NYU Langone Health today announced a new philanthropic investment from longtime supporters Judy and Stewart Colton as part of a $15 million gift shared across three Colton Consortium institutions: NYU Langone, Yale University, and Tel Aviv University.

10 Jun 2026

Immune cell defects may drive celiac disease development

New research from the Snow Centre for Immune Health is challenging long-held assumptions about autoimmune disease, revealing that coeliac disease may be driven not just by an overactive immune system, but by subtle defects in how immune cells function.

9 Jun 2026

CAR-T cell therapy shows promise for treating rheumatoid arthritis

Current therapies for rheumatoid arthritis rely on sustained immunosuppression rather than restoration of immune tolerance, with off-drug remission remaining rare.

3 Jun 2026

Mount Sinai study links long COVID symptoms to autoimmunity

A Mount Sinai-led research team has demonstrated that autoimmunity, where the body's immune system attacks its own tissues, is responsible for the often-debilitating and confounding symptoms of long COVID in a subset of people.

28 May 2026

Study supports routine childhood screening for type 1 diabetes

For ten years, the Fr1da study, coordinated by Helmholtz Munich, has been investigating whether early stages of type 1 diabetes in children can be detected in routine pediatric care.

21 May 2026

A breakthrough molecular discovery could neutralize gluten and protect coeliac patients

A research project led by the Institute for Research in Nutrition and Food Safety (INSA) and the Faculty of Pharmacy and Food Sciences at the University of Barcelona, together with the Molecular Biology Institute of Barcelona (IBMB) of the CSIC (which stands for Consejo Superior de Investigaciones Científicas), has successfully designed and tested a gluten-degrading molecule that is a promising ally in the management of coeliac disease, an autoimmune disease whose symptoms are triggered by the consumption of gluten and other prolamins found in cereals.

14 May 2026