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Inserting tiny scaffolding into the brain could dramatically reduce damage caused by strokes

With funding from the Biotechnology and Biological Sciences Research Council (BBSRC) neurobiologists from the Institute of Psychiatry and tissue engineers from The University of Nottingham have joined forces to tackle the challenge of tissue loss as a result of stroke.

13 Apr 2008

Biomarkers allow doctors to match therapy to patient

Genetic variations ensure that no two people are exactly alike, nor are their cancers.

13 Apr 2008

Iron deficiency cause

The discovery of a gene for a rare form of inherited iron deficiency may provide clues to iron deficiency in the general population – particularly iron deficiency that doesn't respond to iron supplements - and suggests a new treatment approach.

13 Apr 2008

The good and bad side of anti-cancer compounds

Compounds known as "HDAC inhibitors" exhibit cancer-killing activities in cultured cells.

11 Apr 2008

Stem cells and cancer: cancer pathways that also control the adult stem cell population

Speaking at the UK National Stem Cell Network Annual Science Meeting in Edinburgh, Professor Alan Clarke from Cardiff University described his work to investigate a mechanism that normally drives adult stem cells to repair the intestine.

11 Apr 2008

Scientists uncover the potential to control adult stem cells

Research presented at the UK National Stem Cell Network Annual Science Meeting in Edinburgh represents a step towards the use of Adult Stem Cells (ASCs) to repair damaged tissue.

11 Apr 2008

Protein sulfatase 2 a possible treatment target for liver cancer recurrence and survival

Deadly and difficult to treat, liver cancer has long resisted attempts by researchers to develop ways to prolong life and prevent recurrence.

11 Apr 2008

Researchers discover protein leiomodin promotes the assembly of an important heart muscle protein actin

Researchers at the University of Pennsylvania School of Medicine have discovered that a protein called leiomodin (Lmod) promotes the assembly of an important heart muscle protein called actin.

11 Apr 2008

T-cell multiplication unexpectedly delayed after infection

In a surprising outcome that overturns the conventional wisdom on the body's immune response to infection, scientists at The Scripps Research Institute have shown that T cells do not begin proliferation until up to three days after infection.

11 Apr 2008

Phytochemical-rich foods effective at reversing age-related deficits in memory

If you are getting forgetful as you get older, then a research team from the University of Reading and the Peninsula Medical School in the South West of England may have good news for you.

11 Apr 2008

Developing cancer treatments directed at critical developmental pathway

Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells.

11 Apr 2008

Computational approaches to the role of epigenetic marks in transcription regulation

A closer alliance between computational and experimental researchers is needed to make progress towards one of biology's most challenging goals, understanding how epigenetic marks contribute to regulation of gene expression.

11 Apr 2008

Blood vessels: The pied piper for growing nerve cells

Researchers at Johns Hopkins have discovered that blood vessels in the head can guide growing facial nerve cells with blood pressure controlling proteins.

11 Apr 2008

Discovery of gene involved in blood stem cell replication, movement

Researchers at the Joslin Diabetes Center have identified a gene that is responsible for the division and movement of marrow-derived, blood-forming stem cells, a finding that could have major implications for the future of bone marrow and blood cell transplantation.

10 Apr 2008

New understanding of cancer stem cells

By revealing the inner workings of a common cell-to-cell signaling system, University of Michigan biologists have uncovered new clues about mysterious and contentious creatures called cancer stem cells.

10 Apr 2008

Researchers close in on origins of main ingredient of Alzheimer's plaques

The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned.

10 Apr 2008

Power of molecular imaging reveals secrets of the heart

The extraordinary action of a new cellular therapy came to light as a result of powerful PET and SPECT imaging in a recent study reported in the April issue of the Journal of Nuclear Medicine.

10 Apr 2008

Discovery of process behind heart muscle contraction

Researchers from the University of Pittsburgh and the University of Chicago were able to control heart muscle function in a new way after discovering the previously unknown role of two enzymes in heart muscle contraction, as detailed in the April 11 cover story of the Journal of Biological Chemistry.

10 Apr 2008

Molecule delivery method improves stem cell differentiation

Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease.

10 Apr 2008

Module map links embryonic stem cells and cancer stem cells

A new study suggests that a genetic fingerprint associated with normal embryonic stem cells may be important for the development and function of cancer stem cells.

10 Apr 2008