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New insight into breast cancer development in high-risk women

Physicians who treat women with the breast cancer susceptibility gene BRCA1 often remove their patients' ovaries to eliminate the source of estrogen they believe fuels cancer growth.

12 Sep 2007

Ultraconserved non-coding RNAs may be important in human cancer

Research here shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer.

12 Sep 2007

Finasteride unlikely to induce high grade prostate cancers

An increase in high-grade prostate cancer among men taking the drug finasteride is likely caused by an increased detection of cancers, and not by the development of more high-grade cancers, according to two studies published online September 11 in the Journal of the National Cancer Institute.

12 Sep 2007

Fetal neurons play role in adult brain

Subplate neurons - once thought to die after directing the wiring of the cerebral cortex or gray matter - remain in the white matter of the adult brain in small numbers and maintain activity, communicating with other neurons in the brain said researchers from Baylor College of Medicine and the University of Alabama at Birmingham in a report that appears in today's issue of the Journal of Neuroscience

12 Sep 2007

Embryonic stem cell strategy advanced with UCSF finding

UCSF scientists are reporting what they say is a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state, a process that transforms the cells, in essence, into embryonic stem cells.

12 Sep 2007

Customized virus kills brain tumor stem cells that drive lethal cancer

A tailored virus destroys brain tumor stem cells that resist other therapies and cause lethal re-growth of cancer after surgery, a research team led by scientists at the University of Texas M. D. Anderson Cancer Center reports in the Sept. 18 edition of the Journal of the National Cancer Institute.

12 Sep 2007

Diesel exhaust kills throat cells

Researchers at Deakin University have found that diesel exhaust is far more damaging to our health than exhaust from biodiesel, the plant-based fuel.

12 Sep 2007

Sugar key to malaria parasite invasion

Researchers at the Johns Hopkins Malaria Research Institute (JHMRI) have identified a sugar in mosquitoes that allows the malaria-causing parasite, Plasmodium falciparum, to attach itself to the mosquito's gut.

11 Sep 2007

New discovery for Fragile X Syndrome

An important finding has been made by McMaster researchers about Fragile X Syndrome (FXS), a sex-linked genetic disorder that affects approximately one in 4,000 males and one in 6,000 females.

11 Sep 2007

St. Jude follows outcomes of stem cell transplant survivors

Patient care at St. Jude doesn't stop when the child is cured. The end of successful therapy is the start of many years of follow-up care. This care is aimed at helping make the recovery process successful and preparing the family and hometown doctor for long-term complications that might arise from the disease or its treatment.

11 Sep 2007

Potential new drug target for preventing postmenopausal bone loss

Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone.

11 Sep 2007

Tendons found to contain a small subset of previously unknown adult stem cells

Tendon, the cord-like tissue that connects muscle to bone, contains a small subset of previously unknown adult stem cells, scientists at the National Institute of Dental and Craniofacial Research (NIDCR) part of the National Institutes of Health, and their colleagues have discovered.

11 Sep 2007

Using cameras to evaluate your diet!

A Purdue University team plans to help health-conscious people better gauge what's on their plates by using their cell phone cameras.

11 Sep 2007

Mutations in the insulin gene can cause permanent neonatal diabetes

Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections, report researchers from the University of Chicago and Peninsula University (Exeter, UK) in Sept. 18, 2007, issue of the Proceedings of the National Academy of Sciences, published early online.

11 Sep 2007

Mouse model for schizophrenia

Scientists at Johns Hopkins have developed a mouse model for schizophrenia in which a mutated gene linked to schizophrenia can be turned on or off at will.

11 Sep 2007

C-reactive protein shown to be a potential target for cancer treatment

Scientists report that a protein best known as a common marker of inflammation plays a key role in the progression of human cancer.

11 Sep 2007

Vitamin C inhibits the growth of some tumors

Nearly 30 years after Nobel laureate Linus Pauling famously and controversially suggested that vitamin C supplements can prevent cancer, a team of Johns Hopkins scientists have shown that in mice at least, vitamin C - and potentially other antioxidants - can indeed inhibit the growth of some tumors ¯ just not in the manner suggested by years of investigation.

11 Sep 2007

Mechanism identified that plays a critical role in multiple myeloma cell cycle and survival

Researchers at Emory University's Winship Cancer Institute are the first to discover a mechanism that plays a critical role in the multiple myeloma cell cycle and survival.

11 Sep 2007

Shaken not stirred for embryonic stem cells

Embryos spend much of their time in the womb bobbing along with a mother's movement, and, surprisingly enough, new research from the Georgia Institute of Technology and Emory University suggests that embryonic stem cells may develop much better under similarly shaky conditions.

11 Sep 2007

HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia

Therapies leading to longer life for HIV patients have paradoxically increased the prevalence of this condition. Identifying biological markers for the development of HIV–associated dementia is critical both for diagnosing the disorder and for understanding its underlying mechanisms.

11 Sep 2007