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Radiation and drug combo helps boost efficacy of lung cancer treatment

Combining radiation therapy with a drug that helps destroy blood vessels nourishing malignant tumors has been shown in mice to be significantly more effective in treating lung cancer than either approach alone, researchers at UT Southwestern Medical Center have found.

3 Sep 2007

Novel HIV vaccine set for clinical development

A promising new HIV vaccine created at The Wistar Institute has received funding for clinical development aimed at moving the vaccine into human clinical trials as soon as possible.

3 Sep 2007

Nanoparticle drug delivery shows promise for the future of brain tumour therapy

A nanoparticle drug delivery system designed for brain tumour therapy has shown promising tumour cell selectivity in a novel cell culture model devised by scientists at The University of Nottingham. The project, conducted jointly by the Schools of Pharmacy, Biomedical Sciences and Human Development, will be featured in the September issue of the Experimental Biology and Medicine.

3 Sep 2007

University of Utah receives $19.2 Million for HIV research

University of Utah biochemist Wesley I. Sundquist, Ph.D., has been awarded a five-year, $19.2 million National Institutes of Health (NIH) grant to establish an HIV research center to study the structural biology of the AIDS-causing virus.

3 Sep 2007

Interferon alpha revs immune cells but cancer cells ignore it

A new study shows that an important drug used in the treatment of malignant melanoma has little effect on the melanoma cells themselves. Instead, it activates immune-system cells to fight the disease.

3 Sep 2007

First common height gene identified by researchers behind 'obesity gene' finding

Whilst we all know that tall parents are more likely to have tall children, scientists have been unable to identify any common genes that make people taller than others. Now, however, scientists have identified the first gene, known as HMGA2, a common variant of which directly influences height.

3 Sep 2007

Cell that triggers symptoms in allergy attacks can also limit damage

A blood cell known as a troublemaker for triggering the itch and inflammation in allergy attacks, the mast cell, can also calm down the flare-ups, researchers from Stanford University School of Medicine have found.

3 Sep 2007

Cell phone use after bedtime is prevalent among adolescents - contributes to poor sleep

The use of modern means of interpersonal and mass communication has become an essential part of being young. Technology has enabled two people to connect with each other virtually anywhere and at any time, a privilege that, according to new research, is often abused by youngsters and cutting into their sleep time.

3 Sep 2007

A drug-sensitive 'traffic cop' tells potassium channels to get lost

Our brains are buzzing with electrical activity created by sodium and potassium ions moving in and out of neurons through specialized pores. To prevent the constant chatter from descending into chaos the activity of these ion channels has to be tightly regulated.

3 Sep 2007

DES: friend or foe?

The current FDA approved stents (CYPHER and TAXUS) have been associated with late stent thrombosis (LST) (>30days following implantation) however, the mechanisms predictive of LST are poorly understood. Pathologic studies are one of the best methods for detailed analysis of morphologic changes that occur after placement of Drug Eluting Stents to determine the causes of LST.

3 Sep 2007

Carbon nanotubes to fight E. coli

Single-walled carbon nanotubes (SWCNTs) can kill bacteria like the common pathogen E. coli by severely damaging their cell walls, according to a recent report from Yale researchers in the American Chemical Society (ACS) journal Langmuir.

30 Aug 2007

New targets for antibiotics

University of Illinois at Chicago researchers have identified new sites on the bacterial cell's protein-making machinery where antibiotics can be delivered to treat infections.

30 Aug 2007

One species' entire genome discovered inside another's

Scientists at the University of Rochester and the J. Craig Venter Institute have discovered a copy of the entire genome of a bacterial parasite residing inside the genome of its host species.

30 Aug 2007

Neurotransmitter current not flowing through ion channels

In studying how neurotransmitters travel between cells -- by analysis of events in the dimensions of nanometers -- Cornell researchers have discovered that an electrical current thought to be present during that process does not, in fact, exist.

30 Aug 2007

Inhaling nitric oxide helps transplant success

Administering inhaled nitric oxide (NO) during surgery helps protect liver transplant patients from organ failure, according to a new study from researchers at the University of Alabama at Birmingham (UAB).

30 Aug 2007

Microfluidic chambers advance the science of growing neurons

Researchers at the University of Illinois have developed a method for culturing mammalian neurons in chambers not much larger than the neurons themselves.

30 Aug 2007

HPV vaccines may decrease chances of oral cancer

The Centers for Disease Control report that nearly 25 million women are infected with some form of the Human Papilloma Virus (HPV).

30 Aug 2007

How neurotransmitters travel between cells

In studying how neurotransmitters travel between cells - by analysis of events in the dimensions of nanometers - Cornell researchers have discovered that an electrical current thought to be present during that process does not, in fact, exist.

30 Aug 2007

Protein on the surface of platelets plays a key role in cancer-induced platelet aggregation

Scientists have provided new details about how cancer cells spread by surrounding themselves with platelets – the blood cells needed for blood clotting.

30 Aug 2007