B Cell News and Research

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DES: friend or foe?

The current FDA approved stents (CYPHER and TAXUS) have been associated with late stent thrombosis (LST) (>30days following implantation) however, the mechanisms predictive of LST are poorly understood. Pathologic studies are one of the best methods for detailed analysis of morphologic changes that occur after placement of Drug Eluting Stents to determine the causes of LST.

3 Sep 2007

Carbon nanotubes to fight E. coli

Single-walled carbon nanotubes (SWCNTs) can kill bacteria like the common pathogen E. coli by severely damaging their cell walls, according to a recent report from Yale researchers in the American Chemical Society (ACS) journal Langmuir.

30 Aug 2007

New targets for antibiotics

University of Illinois at Chicago researchers have identified new sites on the bacterial cell's protein-making machinery where antibiotics can be delivered to treat infections.

30 Aug 2007

One species' entire genome discovered inside another's

Scientists at the University of Rochester and the J. Craig Venter Institute have discovered a copy of the entire genome of a bacterial parasite residing inside the genome of its host species.

30 Aug 2007

Neurotransmitter current not flowing through ion channels

In studying how neurotransmitters travel between cells -- by analysis of events in the dimensions of nanometers -- Cornell researchers have discovered that an electrical current thought to be present during that process does not, in fact, exist.

30 Aug 2007

Inhaling nitric oxide helps transplant success

Administering inhaled nitric oxide (NO) during surgery helps protect liver transplant patients from organ failure, according to a new study from researchers at the University of Alabama at Birmingham (UAB).

30 Aug 2007

Microfluidic chambers advance the science of growing neurons

Researchers at the University of Illinois have developed a method for culturing mammalian neurons in chambers not much larger than the neurons themselves.

30 Aug 2007

HPV vaccines may decrease chances of oral cancer

The Centers for Disease Control report that nearly 25 million women are infected with some form of the Human Papilloma Virus (HPV).

30 Aug 2007

How neurotransmitters travel between cells

In studying how neurotransmitters travel between cells - by analysis of events in the dimensions of nanometers - Cornell researchers have discovered that an electrical current thought to be present during that process does not, in fact, exist.

30 Aug 2007

Protein on the surface of platelets plays a key role in cancer-induced platelet aggregation

Scientists have provided new details about how cancer cells spread by surrounding themselves with platelets – the blood cells needed for blood clotting.

30 Aug 2007

Researchers chart the level of gene expression in melanoma cell lines

Other than visually inspecting the disease, doctors have no genetic blueprint to classify melanomas, a lethal form of skin cancer.

30 Aug 2007

New anti-cancer drug made from corn lillies kills brain tumor stem cells

A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.

30 Aug 2007

Discovery may lead to new class of diabetes drugs

A multidisciplinary team led by researchers at the University of California, San Diego has determined the structure of a protein found in cells that shows potential as a target for the development of new drugs to treat diabetes.

30 Aug 2007

Contact disorder makes cancer cells mobile

The loss of the protein VMP1 in cancer cells increases their tendency to detach from the initial tumor - the first step towards metastasis.

30 Aug 2007

New method for fighting skin wrinkles

A new method for fighting skin wrinkles has been developed at the Hebrew University Faculty of Agriculture, Food and Environmental Quality Sciences.

30 Aug 2007

Prevalence of algatoxin in the marine environment appears to be increasing

If ingested, for example in seafood, these toxins can lead to discomfort or even illness. The algatoxin yessotoxin (YTX), which is found in both mussels and scallops in Norway, may be a potential disease risk factor in the consumption of seafood. "We don't know the long-term effects of YTX on people", says Monica Suarez Korsnes of the Norwegian School of Veterinary Science (NVH).

30 Aug 2007

Researchers dispute immortal strand hypothesis

How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer?

30 Aug 2007

Third factor identified in obesity-induced Type 2 diabetes

In cases of Type 2 diabetes, the body's cells fail to appropriately regulate blood glucose levels.

30 Aug 2007

Big leap in genomic screening of blood vessels from patient tissue

Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.

30 Aug 2007

Genetics of imatinib resistance in acute lymphoblastic leukemia

In the September 15th issue of Genes & Development, Drs. Richard T. Williams, Willem den Besten, and Charles J. Sherr at Howard Hughes Medical Institute, St. Jude Children's Research Hospital in Memphis TN, lend new insights into how an aggressive form of acute lymphoblastic leukemia (ALL) develops, and how sensitivity to the targeted chemotherapeutic drug, imatinib, can be diminished through interactions between tumor cells and the host microenvironment.

30 Aug 2007