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Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid

Researchers at Weill Cornell Medical College have gotten much closer to understanding how immune-based therapies can treat Alzheimer's disease -- by studying how antibodies go inside brain cells to reduce levels of Alzheimer's-linked amyloid peptides that form plaques between neurons.

24 May 2007

New understanding of how immune-based therapies can treat Alzheimer's disease

24 May 2007

Reducing levels of the protein tau can prevent seizures and neurological deficits related to Alzheimer's disease

The findings, reported in the journal Science, demonstrate that when tau is removed from mice genetically engineered to simulate Alzheimer's disease, their memory function is retained and they live a normal lifespan. Reducing tau levels also made mice more resistant to epileptic seizures.

4 May 2007

Simvastatin may help sufferers with Alzheimer's

Treatment with Simvastatin, one of the statin drugs widely used for lowering cholesterol in humans, significantly improved spatial memory - how to navigate a water maze - in mice genetically bred to have an Alzheimer's like disease.

1 May 2007

Purdue molecule could lead to first drug treatment for Alzheimer's disease

A molecule designed by a Purdue University researcher could lead to the first drug treatment for Alzheimer's disease.

18 Apr 2007

Martek's DHA algal oil reduces brain lesions in Alzheimer's animal model

Martek's proprietary DHA algal oil may slow the development of two brain lesions that are hallmarks of Alzheimer's disease, according to a study featured in the April 18 issue of the Journal of Neuroscience.

18 Apr 2007

Omega-3 fatty acid may help prevent brain lesions

A type of omega-3 fatty acid may slow the growth of two brain lesions that are hallmarks of Alzheimer's disease, UC Irvine scientists have discovered.

18 Apr 2007

Omega-3 fatty acids protect against Alzheimer's

Scientists in the United States say that diets rich in docosahexaenoic acid (DHA) can help prevent the development of the two brain lesions that are hallmarks of Alzheimer's disease.

18 Apr 2007

Molecular mechanism behind aggregation of amyloid beta peptide due to anesthetics

Inhaled anesthetics commonly used in surgery are more likely to cause the aggregation of Alzheimer's disease-related plaques in the brain than intravenous anesthetics say University of Pittsburgh School of Medicine researchers in a journal article published in Biochemistry.

28 Jan 2007

An active mind delays the onset of Alzheimer's

Learning appears to slow the development of two brain lesions that are the hallmarks of Alzheimer's disease, scientists at UC Irvine have discovered. The finding suggests that the elderly, by keeping their minds active, can help delay the onset of this degenerative disease.

23 Jan 2007

Variations in SORL1 gene may factor in development of Alzheimer's disease

Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer's disease, an international team of researchers has discovered. The genetic clue, which could lead to a better understanding of one cause of Alzheimer's, is reported in Nature Genetics online, and was supported in part by the National Institutes of Health (NIH).

14 Jan 2007

Herpes appears to play a role in bringing about Alzheimer's disease

A gene known to be a major risk factor for Alzheimer's disease puts out the welcome mat for the virus that causes cold sores, allowing the virus to be more active in the brain compared to other forms of the gene.

3 Jan 2007

BACE 1 gene may hold the key to Alzheimer's

Canadian scientists have found a specific gene which they believe may hold the key to the degenerative brain disorder Alzheimer's disease.

21 Nov 2006

Yeast model system may provide a means for treating the earliest stage of Alzheimer's

A century ago this month, German psychiatrist Alois Alzheimer formally described characteristics of the neurodegenerative disease which ultimately came to bear his name. While international efforts to learn about Alzheimer's disease and develop treatments have progressed significantly in recent years, a cure remains an elusive goal.

19 Nov 2006

Cabernet Sauvignon may reduce incidence of Alzheimer's Disease

A new study directed by Mount Sinai School of Medicine has found that moderate red wine consumption in a form of Cabernet Sauvignon may help reduce the incidence of Alzheimer's Disease (AD).

20 Sep 2006

Fruit and veggie juice help prevent Alzheimer's

A new study suggests that drinking fruit and vegetable juices frequently may significantly cut the risk of developing Alzheimer's disease.

31 Aug 2006

Boosting enzyme may reverse Alzheimer's

New research by scientists at Columbia University suggests that boosting the function of a certain enzyme may provide a promising strategy for battling Alzheimer's disease, and possibly reversing its effects.

28 Aug 2006

First study to demonstrate IVIg effective longer than a year

A purified mixture of human antibodies called intravenous immunoglobulin (IVIg) provides lasting benefits to patients with Alzheimer's disease (AD), according to researchers at the NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

25 Jul 2006

Researchers find protein associated with brain cell death

Neuroscientists at the Case Western Reserve University School of Medicine have found evidence of which protein in the brain's immune cells triggers a cascade of reactions that produces unregulated free radical production that eventually leads to the neural cell death found in Alzheimer's disease.

19 Jul 2006

Faulty molecule closely linked to Alzheimer's

A recent study directed by Mount Sinai School of Medicine identifies a faulty molecule in the brain found in cases of mild cognitive impairment (MCI).

10 Jul 2006