Biocatalysis News and Research

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Lab-synthesized heparin to transform drug manufacturing

Heparin, the world's most widely used blood thinner, is used during procedures ranging from kidney dialysis to open heart surgery.

18 Mar 2024

New way to create unnatural amino acids identified

Every protein in your body is made up of the same 20 building blocks called amino acids. But just because nature is stuck with a limited toolkit doesn't mean humans can't expand it.

1 Aug 2023

Sphere Fluidics’ Pico-Mine platform chosen by Biosyntia to accelerate synthetic biology and metabolic workflows

Platform selected to accelerate precision fermentation workflows, to support more sustainable and cost-effective manufacturing for active ingredients in vitamins and bioactive.

From Sphere Fluidics 20 Jun 2023

Researchers pioneer a new method for fast miRNA amplification and detection

In the early 1990s, scientists who were studying the development of a roundworm identified a small RNA molecule that regulated the expression of specific genes.

24 Apr 2023

Researchers develop a hairpin-shaped bicyclic peptide to fight cancer

The inhibition of pathological protein-protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer.

12 May 2021

Study investigates activity of enzymes immobilized on gold nanoparticles controlled by infrared laser irradiation

The activity of enzymes in industrial processes, laboratories, and living beings can be remotely controlled using light. This requires their immobilization on the surface of nanoparticles and irradiation with a laser. Near-infrared light can penetrate living tissue without damaging it.

17 Mar 2021

Novel method for creating chemical reactions could unlock many new applications

Scientists have broken the rules of enzyme engineering to unlock a new method for creating chemical reactions that could unlock a wide range of new applications - from creating new drugs to food production.

2 Dec 2020

Research team identifies key ingredients for producing high-value chemical compounds

Researchers have identified key ingredients for producing high-value chemical compounds in an environmentally friendly fashion: repurposed enzymes, curiosity, and a little bit of light.

8 Jun 2020

Bioinspired method detects and detoxifies harmful chemicals in single step

Many industrial and agriculture processes use chemicals that can be harmful for workers and the ecosystems where they accumulate.

12 Aug 2019

Asynt's DrySyn OCTO Mini reaction helps optimize biocatalytic hydrogenation

The DrySyn OCTO Mini reaction station from Asynt is enabling researchers to optimise and expand the applications of HydRegen - an innovative, heterogeneous biocatalytic hydrogenation technology currently under development within the group of Prof. Kylie Vincent at the University of Oxford (UK).

From Asynt 3 Jul 2019

New Prosperity Partnerships projects that link research with industry unveiled

Seven new Prosperity Partnerships projects that will build links between the UK's research base and leading industry partners such as AkzoNobel , AstraZeneca, Google, Rolls-Royce, Tata Steel, and Weir Group, plus small-to-medium enterprise, Oxford PV will be unveiled today by the Engineering and Physical Sciences Research Council (EPSRC) at Prince Philip House, Carlton Terrace, London.

27 Sep 2018

Flow chemistry system helps streamline biocatalysis reactions

An Asia flow chemistry system from Syrris is helping to streamline biocatalysis reactions for researchers at the Biocatalysis and Organic Synthesis Group at the Chemistry Institute of the Federal University of Rio de Janeiro.

From Syrris Ltd 4 Jul 2018

Chemists find new way to make enzymes do a non-natural reaction

Princeton chemists have found a way to make a naturally occurring enzyme take on a new, artificial role, which has significant implications for modern chemistry, including pharmaceutical production.

22 Jun 2018

TU Graz researchers manipulate enzymes to build ring-shaped molecular structures

TU Graz researchers managed for the first time ever to 'retrain' an enzyme to build ring-shaped molecular structures instead of performing its natural task of reducing double bonds.

12 Jun 2018

Research article outlines utilization of calixarenes in biocatalysis and cancer therapy

Calixarenes bear a fascinating class of macrocycles that have served broadly in molecular recognition and supramolecular chemistry.

17 Aug 2016

Enzyme screening kits and samples global distribution agreement signed between Strem and Novozymes

Strem Chemicals, Inc., a manufacturer of specialty chemicals for research and development, and Novozymes, the world’s largest producer of industrial enzymes, today announced the signing of a distribution agreement.

17 Feb 2016

SynTheAll Pharmaceutical wins 2015 CMO Leadership Award

WuXi PharmaTech (Cayman) Inc., a leading open-access R&D capability and technology platform company serving the pharmaceutical, biotechnology, and medical device industries with operations in China and the United States, announced today that SynTheAll Pharmaceutical Co., Ltd., WuXi's small-molecule manufacturing subsidiary, has won a 2015 CMO Leadership Award, which is presented by Life Science Leader magazine based on research conducted by Nice Insight.

30 Jan 2015

libragen contributes to success of PolyModE

libragen, a contract research organization dedicated to biocatalysis and metagenomics, has been a major contributor to the success of PolyModE (Polysaccharide Modifying Enzymes), a large collaborative research project funded by the European Community. The project, which began in 2009 and ended in April this year, looked at developing novel polysaccharide modifying enzymes for the optimized use of hydrocolloids as, for example, food additives or novel therapeutic agents in the food sciences and medical industries. Researchers focused on six industry-targeted hydrocolloids (alginates, carrageenans, chitosans, glycosaminoglycans, pectins, and xanthan gums) where traditional chemistry fails to achieve a certain desired modification.

2 Oct 2013

Almac signs collaboration agreement with DSM in the field of biocatalysis

DSM Pharmaceutical Products, the custom manufacturing and technology business of Royal DSM, announced today that it has signed a collaboration agreement with the Almac Group Ltd. (UK) in the field of biocatalysis to provide sustainable manufacturing services to the pharmaceutical industry.

8 Oct 2012

Researchers announce new method to build important heparin drug

Robert Linhardt is working to forever change the way some of the most widely used drugs in the world are manufactured. Today, in the journal Science, he and his partner in the research, Jian Liu, have announced an important step toward making this a reality. The discovery appears in the October 28, 2011 edition of the journal Science in a paper titled "chemoenzymatic synthesis of homogeneous ultra-low molecular weight heparins."

28 Oct 2011