Biochemistry News and Research

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Study sheds light on complexities of cancer genetics

30 Jul 2012

Fruit flies help pinpoint genetic changes that spell cancer

By studying fruit flies, scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have successfully devised a fast and cost-saving way to uncover genetic changes that have a higher potential to cause cancer. With this new approach, researchers will now be able to rapidly distinguish the range of genetic changes that are causally linked to cancer (i.e. "driver" mutations) versus those with limited impact on cancer progression.

30 Jul 2012

Researchers isolate elusive human gene that causes NMNAT1-related Leber congenital amaurosis

Researchers from the Massachusetts Eye and Ear Infirmary, The Children's Hospital of Philadelphia, Loyola University Chicago Health Sciences Division and their collaborators have isolated an elusive human gene that causes a common form of Leber congenital amaurosis (LCA), a relatively rare but devastating form of early-onset blindness. The new LCA gene is called NMNAT1.

30 Jul 2012

Steak and ticks: A potentially life-threatening experience

Tick bites can trigger a severe, delayed allergic reaction to red meat, suggest findings published in the Journal of General Internal Medicine.

27 Jul 2012

Vaccine complex delivered safely by piggybacking onto 3D DNA nanostructures

In a quest to make safer and more effective vaccines, scientists at the Biodesign Institute- at Arizona State University have turned to a promising field called DNA nanotechnology to make an entirely new class of synthetic vaccines.

27 Jul 2012

A2bAR receptor plays a significant role in regulation of type 2 diabetes and obesity

A recent study led by Boston University School of Medicine (BUSM) demonstrates that the A2b-type adenosine receptor, A2bAR, plays a significant role in the regulation of high fat, high cholesterol diet-induced symptoms of type 2 diabetes.

27 Jul 2012

Rapamycin improves function and extends survival in mice with DCM and rare muscular dystrophies

Rapamycin, an immunosuppressant drug used in a variety of disease indications and under study in aging research labs around the world, improved function and extended survival in mice suffering from a genetic mutation which leads to dilated cardiomyopathy (DCM) and rare muscular dystrophies in humans.

26 Jul 2012

Malaria misdiagnosis: an interview with Dr Toby Leslie

Malaria is caused by a multi-staged parasite which is transmitted by the bite of infected female anopheles mosquitoes. It affects millions of people and kills more than 500,000 people throughout the world every year.

26 Jul 2012

Study identifies 329 instances of potentially inappropriate prescribing in Irish older patients

Research published in the journal Age and Ageing, which studied nursing homes in the Munster region of Ireland, has found that a significant proportion of older patients have either been prescribed a potentially inappropriate medicine or they are not prescribed a medicine that would normally be beneficial.

26 Jul 2012

Human neutrophil peptide 1 effectively prevents HIV entry into cells in multiple ways

Human defensins, aptly named antimicrobial peptides, are made in immune system cells and epithelial cells (such as skin cells and cells that line the gut). One of these peptides, human neutrophil peptide 1, under certain circumstances hinders HIV infection, but exactly how it works remains unclear.

25 Jul 2012

Huddersfield scientist receives Pain Relief Foundation grant for research into BH4 pathway

SOME victims of serious illness experience much less pain than other sufferers, thanks to a natural biochemical variation in the cells of their bodies. Now a scientist at the University of Huddersfield has been awarded research funding that will aid his project to learn more about this variation and therefore develop treatments that could lead to the relief of pain for all patients, with much less dependence on drugs that can have distressing side effects.

19 Jul 2012

Abscisic acid has anti-inflammatory effects in the lungs and gut

Building on previous work with the botanical abscisic acida, researchers in the Nutritional Immunology and Molecular Medicine Laboratory (NIMML) have discovered that abscisic acid has anti-inflammatory effects in the lungs as well as in the gut.

19 Jul 2012

Super-resolution microscopy highlights bacterial biofilms

A multi-fluorescent labeling strategy combined with super-resolution light microscopy has allowed researchers to observe the development of a bacterial biofilm in realtime.

18 Jul 2012

Premier research institutions, Biogen Idec partner to sequence genomes of patients with ALS

Biogen Idec today announced that it has entered into a research collaboration with premier academic and research institutions to sequence the genomes of up to 1,000 patients with amyotrophic lateral sclerosis (ALS) in an effort to gain a deeper understanding about the fundamental genetic causes of ALS.

17 Jul 2012

Functionalised silicas for pharmaceutical purification

Using a specially adapted Asynt 20-litre ReactoMate™ reactor system - PhosphonicS Ltd. (Abingdon, UK) has improved turnaround time and batch-to-batch efficiency for scaling-up production of its range of functionalised silicas.

From Asynt 17 Jul 2012

InvivoSciences, WUSTL to construct artificial tissue models for heart failure

The National Institutes of Health has awarded more than $2 million to a team of scientists from Washington University in St. Louis and InvivoSciences, a biotechnology startup with WUSTL roots, to construct artificial tissue models that will allow the rapid testing of new drugs for heart failure.

17 Jul 2012

New NMR spectrometer to benefit researchers from across Texas A&M

Top-notch molecular research swung into gear at Texas A&M University this week - literally. A crane lowered a high-field 800 megahertz Nuclear Magnetic Resonance spectrometer through an opening in the roof of a biochemistry and biophysics building Wednesday, putting the university on par with leading U.S. research institutions, according to Dr. Gregory Reinhart, department head.

16 Jul 2012

ERBA Diagnostics to showcase full range of products at AACC annual meeting

ERBA Diagnostics, Inc., a fully integrated in vitro diagnostics company, is pleased to announce that Suresh Vazirani, Chairman of ERBA Diagnostics, will be a key note speaker at the International Marketing Brief (IMB) in conjunction with the AACC.

16 Jul 2012

Researchers define interaction between two essential proteins that control inflammation

Researchers at the IRCM, led by geneticist Dr. Jacques Drouin, recently defined the interaction between two essential proteins that control inflammation.

14 Jul 2012

SLU professor to study how antithrombin might prevent premature death from heart disease

Alireza "Ray" Rezaie, Ph.D., professor of biochemistry and molecular biology at Saint Louis University School of Medicine, has received a $1.52 million NIH grant to study how the key blood clotting inhibitor antithrombin might be exploited to prevent premature death from heart disease.

12 Jul 2012

Biochemistry News and Research

Study sheds light on complexities of cancer genetics

Fruit flies help pinpoint genetic changes that spell cancer

Researchers isolate elusive human gene that causes NMNAT1-related Leber congenital amaurosis

Steak and ticks: A potentially life-threatening experience

Vaccine complex delivered safely by piggybacking onto 3D DNA nanostructures

A2bAR receptor plays a significant role in regulation of type 2 diabetes and obesity

Rapamycin improves function and extends survival in mice with DCM and rare muscular dystrophies

Malaria misdiagnosis: an interview with Dr Toby Leslie

Study identifies 329 instances of potentially inappropriate prescribing in Irish older patients

Human neutrophil peptide 1 effectively prevents HIV entry into cells in multiple ways

Huddersfield scientist receives Pain Relief Foundation grant for research into BH4 pathway

Abscisic acid has anti-inflammatory effects in the lungs and gut

Super-resolution microscopy highlights bacterial biofilms

Premier research institutions, Biogen Idec partner to sequence genomes of patients with ALS

Functionalised silicas for pharmaceutical purification

InvivoSciences, WUSTL to construct artificial tissue models for heart failure

New NMR spectrometer to benefit researchers from across Texas A&M

ERBA Diagnostics to showcase full range of products at AACC annual meeting

Researchers define interaction between two essential proteins that control inflammation

SLU professor to study how antithrombin might prevent premature death from heart disease

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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