Functionalised silicas for pharmaceutical purification

Using a specially adapted Asynt 20-litre ReactoMate™ reactor system - PhosphonicS Ltd. (Abingdon, UK) has improved turnaround time and batch-to-batch efficiency for scaling-up production of its range of functionalised silicas.


Using proprietary immobilisation technology, PhosphonicS Ltd. has developed a range of functionalised silicas for pharmaceutical purification and heterogeneous catalysis operations. The materials enable metal residue levels in drug substances (APIs) to be reduced to very low, regulated levels and precious metals to be effectively scavenged from spent catalysis reactions.

Michael Suggate, Laboratory Production Manager at PhosphonicS Ltd. commented "Traditionally our scientists relied upon 5-litre heating mantles to scale-up production of our functionalised silicas from tens of grams to initial kilo quantities. However this technology suffered in terms of the initial scale-up speed we desired".

He added "Implementing the Asynt ReactoMate system has given us the benefits of greater comparison to pilot scale chemistry, better heat and mass transfer and far greater control than heating mantles. The unique stand that the ReactoMate reactor sits on allows for complete access to the filter port and the adjustable height allows us to filter our solids with far greater control (under gravity) than by lifting and pouring from large round bottomed flasks".

For further information on ReactoMate reactor systems please contact Asynt (+44-1638-781709 / [email protected]) or visit For further information on PhosphonicS Ltd. and its range of innovative functionalised silica systems please visit

Asynt is a leading supplier of affordable products, consumables and services for chemists in industry and academia.  With staff of trained chemists - Asynt is able to draw upon this in-depth applications knowledge to provide a high level of customer support for its DrySyn Heating Blocks, Controlled Lab Reactors, Synthesis Tools, Evaporators, Circulators, Temperature Control Systems, Vacuum Pumps and Laboratory Safety Equipment.



Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Asynt. (2023, March 22). Functionalised silicas for pharmaceutical purification. News-Medical. Retrieved on March 28, 2023 from

  • MLA

    Asynt. "Functionalised silicas for pharmaceutical purification". News-Medical. 28 March 2023. <>.

  • Chicago

    Asynt. "Functionalised silicas for pharmaceutical purification". News-Medical. (accessed March 28, 2023).

  • Harvard

    Asynt. 2023. Functionalised silicas for pharmaceutical purification. News-Medical, viewed 28 March 2023,


The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment
You might also like...
Asynt's DrySyn Scholar Kit used for safe heating of round bottom flasks in academic laboratories