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AI redesign helps enzymes evolve beyond natural limits

Researchers showed that AI-redesigned botulinum neurotoxin proteases provided more stable starting points for directed evolution, allowing enzymes to access beneficial mutations that were poorly tolerated in wild-type backgrounds. In BoNT/E models, the approach improved activity, evolvability, and specificity, including an ataxin-2-targeting variant with markedly reduced cleavage of the native SNAP25 substrate.

24 Jul 2026

Bio-inspired ear probe may enhance early hearing loss diagnosis

Binghamton University Assistant Professor Jian Zhou, PhD '18, will lead a five-year, $1.84 million project funded by the National Institutes of Health to create a dual-sensing ear canal probe that will more accurately and reliably detect otoacoustic emissions.

23 Jul 2026

Scientists create programmable immune receptors for disease-resistant crops

Crop production faces threats from plant pathogens. Traditional disease-resistance breeding relies heavily on natural plant resistance genes that encode immune receptors adapted to particular pathogens.

23 Jul 2026

Computationally designed antibody attacks previously untreatable KRAS cancer mutations

Antibodies are like "guided missiles" that find and attack cancer cells, but cancer-causing mutations inside cells have remained a "blind spot" for treatment because antibodies cannot reach them.

23 Jul 2026

New model holds promise as a non-invasive, low-cost tool for MAFLD screening

Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a predominant cause of chronic liver disease, underscoring the demand for accessible, non-invasive diagnostic tools.

23 Jul 2026

Researchers develop artery-on-a-chip platform to predict stroke risk

Predicting an individual's risk of ischemic stroke is difficult because thrombosis embolization-the process of a blood clot detaching from the area where it formed and traveling to and then sticking in another blood vessel-is based on factors that are unique to each person.

23 Jul 2026

TriLink BioTechnologies® further strengthens global IP position with newly issued patent in China for CleanCap® capping technology

TriLink BioTechnologies, LLC (TriLink®), a Maravai LifeSciences company and global provider of life science reagents and services, has been granted a new patent from the China National Intellectual Property Administration (CNIPA), Patent number ZL 2025 11246578.X, covering methods of synthesizing RNA molecules.

From TriLink Biotechnologies 23 Jul 2026

New imaging platform tracks hundreds of neurons at unprecedented depths

The brain is a vast, densely interconnected network of neurons computing in parallel. Watching these computations unfold in real time could reveal how the brain processes sensation and guides behavior.

23 Jul 2026

AI platform uncovers promising target for chronic pain treatmen

Despite the widespread availability of analgesics, pain management remains one of the most significant and pervasive challenges in modern medicine, with more than 20% of the global population suffering from chronic pain, especially chronic neuropathic pain characterized by central sensitization.

22 Jul 2026

Handheld breathalyzer enables precise monitoring of fat metabolism

Researchers from ETH Zurich have developed a portable measuring device that detects the metabolic marker acetone in breath almost as accurately as a mass spectrometer.

22 Jul 2026

New study uses sleep monitoring and AI to detect Alzheimer's

Researchers from Universidad Carlos III de Madrid (UC3M) and Hospital Universitario Severo Ochoa in Leganés, part of the public health network of the Comunidad de Madrid, have developed a methodology that uses artificial intelligence (AI) to analyze brain electrical activity during sleep and facilitate the early diagnosis of Alzheimer's.

22 Jul 2026

New photothermal therapy overcomes major cancer treatment barriers

In a promising development for cancer treatment, a collaborative research team has overcome two issues that have prevented photo thermal therapy, a much less invasive treatment option than surgery and/or radiation, from becoming more common.

22 Jul 2026

arcoris bio and Europa Biosite partner to bring immunoMUSE® kits to Europe and North American market

arcoris bio, a Swiss life science research tools and in vitro diagnostics company, today announced a distribution partnership with Europa Biosite, a leading distributor of life science research products and services.

From arcoris bio AG 21 Jul 2026

Simple changes to surgical tools may reduce swallowing complications after neck surgery

Rice University mechanical engineers and Baylor College of Medicine neurosurgeons have identified simple changes to surgical tools that could reduce strain on the esophagus and potentially lower the risk of swallowing difficulties after neck surgery.

21 Jul 2026

Human experts remain essential for checking clinical AI outputs

In a Rwanda-based evaluation, LLM judges produced consistent and far cheaper ratings of clinical AI responses but matched local clinician ratings on only a minority of assessment criteria. They consistently missed potential demographic bias, indicating that human expert evaluation remains important despite AI’s potential role in initial screening.

21 Jul 2026

UVA researcher wins federal grant to develop tools for studying rare circulating cells

A University of Virginia School of Engineering and Applied Science faculty researcher earned a major new federal grant to develop emerging tools to work with some of the rarest circulating cells in the human body, a step toward better treatments for diseases such as cancer and infection.

21 Jul 2026

Automated workflow speeds bacterial sample preparation for genetic sequencing

Biomedical engineers at Brown University have developed a fully automated workflow that simplifies and accelerates the preparation of bacterial samples for genetic sequencing.

21 Jul 2026

AI-powered PeptiVerse could accelerate peptide drug discovery

Penn Engineers have developed PeptiVerse, an AI-powered platform that predicts key chemical and biological properties of peptides, the strings of amino acids whose medical potential has been demonstrated by the success of GLP-1 drugs, the widely used weight-loss treatments.

21 Jul 2026

New light-sheet imaging system tracks brain seizure dynamics in 3D

Seizures can race through the brain in seconds, making them difficult to capture in detail. To overcome this challenge, researchers have developed a new high-resolution light-sheet imaging system that is fast enough to image seizure propagation in the brain of a larval zebrafish in 3D.

21 Jul 2026

New AI framework prioritizes high quality patient care in hospitals

A UVA Health emergency medicine doctor and colleague at Clemson University have developed a framework to help hospitals integrate artificial intelligence to not just increase efficiency and cut costs but ensure high-quality patient care remains the top priority.

21 Jul 2026