Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

MRC researchers discover genetic 'switch' that plays key role in Parkinson's disease

A genetic 'switch' has been discovered by MRC researchers at the University of Leicester which could help to prevent or delay the symptoms of Parkinson's disease.

17 Feb 2017

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

The Helmholtz Zentrum München has published results of the largest genome-wide association study on proteomics to date.

16 Feb 2017

UNIGE researchers develop new technique to improve diagnosis of genetic diseases

When a child is conceived, he or she receives DNA from both parents. The child's own genome thus consists of a maternal and a paternal genome. However, some genes — about 100 out of the 20,000 encoded genes— are exclusively expressed either from the maternal or from the paternal genome, with the other copy of the gene remaining silent.

16 Feb 2017

Scientists develop new bioinformatics tool to make biological experiments more transparent

Biological experiments are generating increasingly large and complex sets of data. This has made it difficult to reproduce experiments at other research laboratories in order to confirm - or refute - the results.

15 Feb 2017

Kent researchers identify how Ebola viruses need few mutations to adapt to new host species

Kent researchers have identified how few mutations it can take for Ebolaviruses to adapt to affect previously resistant species.

15 Feb 2017

Scientists identify genetic signature of risk for type 2 diabetes

Why do some people get Type 2 diabetes, while others who live the same lifestyle never do? For decades, scientists have tried to solve this mystery - and have found more than 80 tiny DNA differences that seem to raise the risk of the disease in some people, or protect others from the damagingly high levels of blood sugar that are its hallmark.

14 Feb 2017

Newly discovered breast stem cells wake up when exposed to ovarian hormones

Walter and Eliza Hall Institute researchers have used advanced cellular, bioinformatics and imaging technology to reveal a long-lived type of stem cell in the breast that is responsible for the growth of the mammary glands during pregnancy.

13 Feb 2017

Researchers identify molecular signatures to predict efficacy of malaria vaccines

The acid test for a vaccine is: "Does it protect people from infection?" Emory Vaccine Center researchers have analyzed this issue for a leading malaria vaccine called RTS,S, and their results have identified candidate signatures, or biomarkers, in the blood of vaccinated subjects which predict the likelihood of success from vaccination.

13 Feb 2017

Scientists apply generative neural network to create new pharmaceutical medicines

Scientists from Mail.Ru Group, Insilico Medicine and MIPT have for the first time applied a generative neural network to create new pharmaceutical medicines with the desired characteristics.

9 Feb 2017

Scientists secure NIH grant to test portable blood-adhesion monitor for sickle cell disease patients

Researchers at Case Western Reserve University will use a $2 million grant from the National Institutes of Health to develop and test a small, portable blood-adhesion monitor for sickle cell disease patients.

8 Feb 2017

NMR and metabolic phenotyping

In this interview, Dr Harmut Schafer introduces the work being done at the Phenome Center in Birmingham, on metabolic phenotyping using NMR.

From Bruker BioSpin - NMR, EPR and Imaging 31 Jan 2017

Novel potassium channel genes could be promising therapeutic targets for alcohol use disorder

A handful of FDA-approved drugs exist for treating individuals with alcohol use disorder but they have been largely ineffective at reducing the high rates of relapse. As such, there remains a critical need to identify and develop alternative pharmacological treatment options.

31 Jan 2017

Research consortium awarded $21 million NIH grant to find ways to prevent epilepsy in patients with TBI

An international consortium of academic research institutions have been awarded a $21 million grant from the National Institutes of Health to develop better ways to prevent epilepsy in patients who have suffered traumatic brain injuries.

30 Jan 2017

Scientists decipher emergence of neuronal diversity in the cerebral cortex

The development of cerebral cortex plays a major role in the evolution of species and in particular for mankind.

30 Jan 2017

University of Freiburg offers infrastructure and data services to support life science research

The University of Freiburg has set up infrastructure and services to support researchers across Europe in the fields of biology, medicine, and pharmacy with the analysis of very large data sets.

30 Jan 2017

Genetic makeup of social partners influences health, mice study shows

Researchers at the European Bioinformatics Institute (EMBL-EBI) have shown that the health of individual mice is influenced by the genetic makeup of their partners. Their findings, published in PLOS Genetics, indicate that research into genetics and disease should include the genotypes of both individuals and their partners.

27 Jan 2017

Researchers show how social environment can have large impact on weight and health in mice

The genetics of nearby mice can have a large impact on one animal's weight and health, according to a report by Amelie Baud and Oliver Stegle of the European Bioinformatics Institute (EMBL - EBI) in Hinxton, United Kingdom, published on January 25th, 2017 in PLOS Genetics.

25 Jan 2017

Increasing idiopathic pulmonary fibrosis research

IPF is an incurable lung condition with the average life expectancy following diagnosis being just three years. It’s one of the many types of interstitial lung disease (ILD). Interstitial means that the disease affects the interstitium, a lace-like network of tissue that supports the air sacs (alveoli) in your lungs.

From Asthma + Lung UK 25 Jan 2017

New drugs that target neighbour proteins may help halt cancer progression

Cancer is caused by an accumulation of genetic changes in a cell, that overcome the normal checks and balances leading to uncontrolled growth. A complex, interacting network of proteins controls all of a cell's processes, from metabolism to growth and division.

24 Jan 2017

Advanced NMR-based methods for studying RNPs and drug design

Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical tool widely used in chemical research to investigate the structure and dynamics of molecules.

From Bruker BioSpin - NMR, EPR and Imaging 24 Jan 2017

Bioinformatics News and Research

Further Reading

MRC researchers discover genetic 'switch' that plays key role in Parkinson's disease

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

UNIGE researchers develop new technique to improve diagnosis of genetic diseases

Scientists develop new bioinformatics tool to make biological experiments more transparent

Kent researchers identify how Ebola viruses need few mutations to adapt to new host species

Scientists identify genetic signature of risk for type 2 diabetes

Newly discovered breast stem cells wake up when exposed to ovarian hormones

Researchers identify molecular signatures to predict efficacy of malaria vaccines

Scientists apply generative neural network to create new pharmaceutical medicines

Scientists secure NIH grant to test portable blood-adhesion monitor for sickle cell disease patients

NMR and metabolic phenotyping

Novel potassium channel genes could be promising therapeutic targets for alcohol use disorder

Research consortium awarded $21 million NIH grant to find ways to prevent epilepsy in patients with TBI

Scientists decipher emergence of neuronal diversity in the cerebral cortex

University of Freiburg offers infrastructure and data services to support life science research

Genetic makeup of social partners influences health, mice study shows

Researchers show how social environment can have large impact on weight and health in mice

Increasing idiopathic pulmonary fibrosis research

New drugs that target neighbour proteins may help halt cancer progression

Advanced NMR-based methods for studying RNPs and drug design

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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