Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Florida Hospital and VTT of Finland collaborate to predict early onsets of Alzheimer's disease

In an effort to better understand the development of Alzheimer's disease, Florida Hospital Neuroscience Institute and VTT Technical Research Centre of Finland are collaborating to identify the biomarker assay that may predict early onsets of the disease.

18 Sep 2013

Mayo Clinic to host annual Individualizing Medicine Conference from Sept. 30 to Oct. 2

From Promise to Practice is the title and the main message of the second annual Individualizing Medicine Conference at Mayo Clinic, Sept. 30-Oct. 2. Physicians from more than 40 states and several countries will be arriving in Minnesota to hear and learn about the latest developments and research in genomic research and how to move these discoveries into the medical practice.

18 Sep 2013

NIEHS grant renewal opens next chapter in 18-year research effort into brain injury biomarker

The National Institute of Environmental Health Sciences (NIEHS) has awarded a five-year, $1.5 million grant extension to Columbia University's Mailman School of Public Health to fund research into the function of a biomarker for brain injury called Translocator Protein 18 kDa, better known as TSPO, in order to better understand its function in brain injury and inflammation and discover targets for therapy.

17 Sep 2013

Study reports identification of IDH1 protein as novel biomarker for diagnosis of NSCLC

A protein called isocitrate dehydrogenase is present at high levels in lung cancers and can be detected in the blood, making it a noninvasive diagnostic marker for lung cancers, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

17 Sep 2013

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

New research shows that microRNA-486 is a potent tumor-suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung-cancer cells, and the induction of programmed cell death, or apoptosis, in those cells.

17 Sep 2013

Repeated exposure to low level blasts causes harmful effects in brain

Repeated exposure to low level blasts (LLB) can cause symptoms similar to sports concussion. Soldiers or law enforcement officers called "breachers" receive training in using low level blasts for forced entry.

17 Sep 2013

Gentris expands genomic biomarker offering with launch of Affymetrix GeneChip HTA services

Gentris Corporation, a global leader in pharmacogenomics and biorepository solutions, announced today that it is expanding its genomic biomarker offering with the launch of Affymetrix GeneChip Human Transcriptome Array services.

17 Sep 2013

Researchers identify biomarker that can predict diabetes risk

Researchers at the Vanderbilt Heart and Vascular Institute and Massachusetts General Hospital have identified a biomarker that can predict diabetes risk up to 10 years before onset of the disease.

17 Sep 2013

Three-gene biomarker can help determine treatment option for early prostate cancer

The level of expression of three genes associated with aging can be used to predict whether seemingly low-risk prostate cancer will remain slow-growing, according to researchers at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center.

13 Sep 2013

Wistar Institute receives $1.5M grant to prepare potential new prostate cancer drug for clinical use

To prepare a potential new prostate cancer drug, called Gamitrinib, for trial in humans, The Wistar Institute has received a $1.5 million grant from the US Department of Defense's Congressionally Directed Medical Research Program.

13 Sep 2013

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Amgen today announced the publication of a biomarker analysis of Vectibix (panitumumab) in combination with FOLFOX, a type of oxaliplatin-based chemotherapy, for the first-line treatment of patients with metastatic colorectal cancer.

12 Sep 2013

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

A family of microRNAs (miR-200) blocks cancer progression and metastasis by stifling a tumor's ability to weave new blood vessels to support itself, researchers at The University of Texas MD Anderson Cancer Center report today in Nature Communications.

12 Sep 2013

Ventana gets CFDA approval for VENTANA ALK immunohistochemistry assay

Ventana Medical Systems, Inc., a member of the Roche Group, today announced the approval of the VENTANA ALK immunohistochemistry assay by the Chinese Food and Drug Administration as a companion diagnostic to aid in the identification of patients for Pfizer's CFDA-approved oncology product XALKORI (crizotinib).

12 Sep 2013

Berg receives Drug Discovery Technology Innovation Award for agnostic approach to drug discovery

Berg, a biopharmaceutical company committed to uncovering health solutions through a data-driven, biological research approach, was recognized today with the 2013 North American Drug Discovery Technology Innovation Award at the Frost & Sullivan Growth, Innovation and Leadership Awards Gala, the annual event by the global research organization that highlights the most promising new innovative technology across sectors.

12 Sep 2013

Study: More than 70% of bladder tumors display somatic mutations in TERT gene

Researchers from the Spanish National Cancer Research Centre (CNIO) have discovered that more than 70% of bladder tumours display somatic mutations in the TERT gene (telomerase reverse transcriptase).

11 Sep 2013

Banook Central Imaging, Oncodesign partner to expand use of new approaches in pharmaco-imaging

Oncodesign, a contract research laboratory dedicated to the discovery of new anticancer therapies, and Banook Central Imaging, a company specializing in the centralized reading of medical images, today announce the start of a partnership to expand the use of new approaches in pharmaco-imaging.

10 Sep 2013

S&P Capital IQ commences Standard & Poor's Factual Stock Report coverage on Epigenomics AG

S&P Capital IQ announced today that it has commenced Standard & Poor's Factual Stock Report coverage on Epigenomics AG.

7 Sep 2013

Biomarker strategy in suspected ACS patients has potential to change clinical practice

An emergency department strategy that uses two biomarkers to triage patients with suspected acute coronary syndrome (ACS) can increase the rate of early, safe hospital discharge, according to results of the Biomarkers in Cardiology 8 (BIC-8) trial.

5 Sep 2013

High sensitive troponin test may help doctors improve diagnosis in patients with heart attack

Abbott (NYSE: ABT) announced today promising preliminary results from a study presented at the ESC Congress 2013, suggesting that its high sensitive troponin test may help doctors improve the diagnosis and prognosis of patients presenting with symptoms of a heart attack.

4 Sep 2013

VolitionRx-led consortium receives grant to develop novel NuQ biomarkers for immune response

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3 Sep 2013

Biomarker News and Research

Further Reading

Florida Hospital and VTT of Finland collaborate to predict early onsets of Alzheimer's disease

Mayo Clinic to host annual Individualizing Medicine Conference from Sept. 30 to Oct. 2

NIEHS grant renewal opens next chapter in 18-year research effort into brain injury biomarker

Study reports identification of IDH1 protein as novel biomarker for diagnosis of NSCLC

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

Repeated exposure to low level blasts causes harmful effects in brain

Gentris expands genomic biomarker offering with launch of Affymetrix GeneChip HTA services

Researchers identify biomarker that can predict diabetes risk

Three-gene biomarker can help determine treatment option for early prostate cancer

Wistar Institute receives $1.5M grant to prepare potential new prostate cancer drug for clinical use

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

Ventana gets CFDA approval for VENTANA ALK immunohistochemistry assay

Berg receives Drug Discovery Technology Innovation Award for agnostic approach to drug discovery

Study: More than 70% of bladder tumors display somatic mutations in TERT gene

Banook Central Imaging, Oncodesign partner to expand use of new approaches in pharmaco-imaging

S&P Capital IQ commences Standard & Poor's Factual Stock Report coverage on Epigenomics AG

Biomarker strategy in suspected ACS patients has potential to change clinical practice

High sensitive troponin test may help doctors improve diagnosis in patients with heart attack

VolitionRx-led consortium receives grant to develop novel NuQ biomarkers for immune response

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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