Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

SomaLogic, Novartis enter multi-year research agreement

SomaLogic, Inc., announced today that it has entered into a multi-year research agreement with Novartis to use its unique proprietary proteomics technology to accelerate Novartis' drug discovery and development efforts.

19 Oct 2011

LRI launches major lupus research initiative

The Lupus Research Institute (LRI) launched a major international initiative aimed at attracting the highest level scientists to conduct pioneering research to discover the fundamental root causes of lupus, explore the potential for a cure, and transform the field of lupus research.

18 Oct 2011

NextBio predicts mechanisms underlying drug toxicity and identifies new cancer biomarker

New research presented this week highlights the ability of NextBio to help life scientists and clinicians investigate publicly available genomic data to assess biological mechanisms underlying drug toxicity, as well as discover prospective cancer biomarkers for further validation.

15 Oct 2011

GFAP protein levels can help identify HIE in newborns

Johns Hopkins researchers have discovered that increased blood levels of a protein specific to central nervous system cells that are vital to the brain's structure can help physicians identify newborns with brain injuries due to lack of oxygen.

14 Oct 2011

Study: miR-34b gene associated with aggressive form of melanoma

A certain microRNA gene, miR-34b, could be a useful biomarker in early diagnosis of the most lethal forms of melanoma, according to new research published by KGI Professor Animesh Ray and his research collaborators.

14 Oct 2011

Autism Speaks announces 10 new research grants

Autism Speaks, the world's largest autism science and advocacy organization, today announced the awarding of 10 new research grants totaling $1,782,934 in funding over the next three years. The selected studies will evaluate the effectiveness of a broad array of promising behavioral and medical treatments for core symptoms and associated medical issues in children, adolescents, and adults with autism spectrum disorders.

13 Oct 2011

NanoString introduces nCounter Analysis System

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, today announced the launch of its second generation nCounter Analysis System.

From NanoString Technologies 13 Oct 2011

USPTO issues patent to Oragenics' In Vivo Induced Antigen Technology

Florida-based nutraceutical company, Oragenics, Inc., announced today the issuance of patent number 8,034,571 from the United States Patent and Trademark office for In Vivo Induced Antigen Technology.

13 Oct 2011

CSIR and Mayo Clinic sign research collaboration agreement

Mayo Clinic and the top science and technology organization in India have signed an agreement to collaborate on research. Leaders from Mayo and Council of Scientific and Industrial Research (CSIR), India today signed a memorandum of understanding to work together on such topics as drug, device and biomarker studies relating to heart disease, chemical biology and applied genomics, and innovations in metabolomics.

13 Oct 2011

Two-gene DNA urine test for prostate cancer

In the current debate sparked by the recent USPSTF recommendation on PSA screening, it is clear that better biomarkers than PSA are urgently needed. One new biotechnology that may go a long way in detecting only prostate cancer and reducing unnecessary prostate cancer biopsies and possible subsequent overtreatment, is the development of a new urine test for prostate cancer.

12 Oct 2011

Journal of Alzheimer's Disease supplement explores neuroimaging

Alzheimer's disease (AD) is a common problem that is becoming progressively burdensome throughout the world. A new supplement to the Journal of Alzheimer's Disease, Imaging the Alzheimer Brain, clearly shows that multiple imaging systems are now available to help understand, diagnose, and treat the disease.

12 Oct 2011

Roche's gantenerumab removes amyloid plaques from the brain of patients with AD

Roche today announced the publication of a study demonstrating that its monoclonal antibody gantenerumab removes amyloid plaques from the brain of patients with Alzheimer's disease. The study "Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab" is published today in the October issue of Archives in Neurology.

11 Oct 2011

USPTO awards HistoRx two patents for methods of standardization of digital microscopy instruments

HistoRx, the leader in quantitative immunohistochemistry, advances its proprietary position in digital pathology through the recent issuance of US patents covering key features necessary for achievement of reproducible, standardized image analysis results.

7 Oct 2011

USDTL releases CordStat EtOH assay screens for newborn alcohol exposure in utero

United States Drug Testing Laboratories (USDTL), a reference laboratory specializing in alcohol and drugs of abuse testing, released a new assay testing umbilical cord for newborn alcohol exposure in utero on Monday, October 3, 2011.

3 Oct 2011

Amorfix achieves 85% specificity and sensitivity with EP-AD CSF Diagnostic Test for AD

Amorfix Life Sciences, a product development company focused on diagnostics and therapeutics for misfolded protein diseases, today announced it has achieved 85 percent specificity and sensitivity with its EP-AD CSF Diagnostic Test.

1 Oct 2011

Alnylam commences ALN-PCS Phase I trial in severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-PCS, an RNAi therapeutic targeting proprotein convertase subtilisin/kexin type 9, or PCSK9, for the treatment of severe hypercholesterolemia.

27 Sep 2011

YM BioSciences total revenue decreases to $1.5 million for fiscal 2011

YM BioSciences Inc., a drug development company advancing a diverse portfolio of promising hematology and cancer-related products, today reported operational and financial results for its 2011 fiscal year, ended June 30, 2011.

23 Sep 2011

Data from Amgen's XGEVA and Vectibix studies to be presented at EMCC 2011

Amgen announced today that data from XGEVA (denosumab) and Vectibix (panitumumab) studies will be presented at the 2011 European Multidisciplinary Cancer Congress, Sept. 23 - 27, 2011, in Stockholm, Sweden.

23 Sep 2011

New assay simultaneously visualize gene number, protein expression in individual cells

Researchers have discovered a method for simultaneously visualizing gene number and protein expression in individual cells. The fluorescence microscopy technique could permit a detailed analysis of the relationship between gene status and expression of the corresponding protein in cells and tissues, and bring a clearer understanding of cancer and other complex diseases, according to researchers who led the study

23 Sep 2011

CoPlex, Hawthorn sign license agreement for hawAD14 Alzheimer's drug

CoPlex Therapeutics has signed an exclusive global license agreement with Hawthorn Pharmaceuticals to develop and commercialize hawAD14, a preclinical oral small molecule candidate for the treatment of Alzheimer's and other neurodegenerative diseases.

23 Sep 2011