Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Almac's Clinical Services business unit receives ASQ certification

Almac's Clinical Services business unit was presented with the 'ASQ Philadelphia Section Large Company Member of the Year' award at the section's awards dinner held at the Timber Room at Wegmans in Malvern, PA on 22 June. The award is presented annually to the company with more than 200 employees with the leading participation in section activities.

19 Jul 2011

Preliminary data from Amorfix human diagnostic test for Alzheimer's presented at ICAD

Amorfix Life Sciences, a product development company focused on diagnostics and therapeutics for misfolded protein diseases, presented a paper on Sunday July 17th, 2011 at the International Conference on Alzheimer's disease in Paris, France.

19 Jul 2011

Roche signs agreement to acquire mtm laboratories

Ventana Medical Systems, Inc., a member of the Roche Group, announced today that Roche has signed an agreement under which it will acquire 100 percent of mtm laboratories AG (mtm), a privately-held company based in Heidelberg, Germany.

From Roche Sequencing and Life Science 19 Jul 2011

Cardinal Health opens The Center for the Advancement of Molecular Imaging in Phoenix

Today in Phoenix, Cardinal Health opened The Center for the Advancement of Molecular Imaging – a new, first-of-its-kind collaboration laboratory that will expedite the development of nuclear imaging agents that treat complex diseases like cancer, heart disease and neurological disorders.

18 Jul 2011

Global research initiatives to standardize Alzheimer's biomarkers

As the Alzheimer's field moves closer to new and earlier tests for the disease, innovative global research initiatives are taking the first important steps to standardize Alzheimer's biomarkers, as evidenced by two presentations made today at the Alzheimer's Association(R) International Conference 2011 (AAIC 2011) in Paris.

18 Jul 2011

Grape seed polyphenols may help prevent Alzheimer's disease

Researchers at Mount Sinai School of Medicine have found that grape seed polyphenols—a natural antioxidant—may help prevent the development or delay the progression of Alzheimer's disease.

16 Jul 2011

Study sheds light on the way antibodies distinguish between different 'biomarkers'

A new research paper sheds light on the way antibodies distinguish between different but closely related 'biomarkers' - proteins which reveal information about the condition of the human body.

15 Jul 2011

Scientists identify new metabolic pathway for breast cancer

Agios Pharmaceuticals, the leading biopharmaceutical company focused on discovering and developing novel drugs in the rapidly emerging field of cancer metabolism, announced today a publication in the journal Nature that identifies dysregulated activity of the serine pathway as a novel metabolic target in certain breast cancers.

15 Jul 2011

DVS Sciences completes $14.6M series A financing

The Ontario Institute for Cancer Research (OICR) and DVS Sciences Inc., today announced that DVS Sciences has completed a $14.6 million series A financing.

14 Jul 2011

Scientists link human gene to risk of developing Mild Cognitive Impairment

Connecting a human gene to the risk of developing the Alzheimer's precondition known as Mild Cognitive Impairment has been somewhat of a holy grail for scientists, but a team led by researchers from Cornell University has ended the quest.

14 Jul 2011

Kinexus introduces new KiNET-Antibody Microarray website

Kinexus Bioinformatics Corporation, a world-leader in molecular intelligence research, announced a major expansion in its KiNET DataBank for the study of cell communication systems with the launch of the KiNET-Antibody Microarray website.

13 Jul 2011

Men more likely to succumb to cancer

According to a new analysis of 36 different types of tumors and blood cancers that affect both sexes, men are more likely than women to get and die of cancer. The report shows that leukemia and cancers of the colon and rectum, pancreas, and liver killed about one and a half to two times as many men as women in the U.S. over a 30-year period. Lung cancer killed nearly two and a half times as many men during that time. According to the American Cancer Society men have about a 1 in 2 chance of developing cancer at some point in their lives, compared with women, who have a 1 in 3 chance.

13 Jul 2011

Researchers identify biomarker for familial risk of autism

Siblings of people with autism show a similar pattern of brain activity to that seen in people with autism when looking at emotional facial expressions. The University of Cambridge researchers identified the reduced activity in a part of the brain associated with empathy and argue it may be a 'biomarker' for a familial risk of autism.

13 Jul 2011

Affymetrix commences shipment of gene profiling reagents

Affymetrix, Inc. today began shipping its FDA-cleared Gene Profiling Reagents. Affymetrix also announced the availability of the new Gene Profiling Array cGMP U133 P2, a version of the widely cited Human Genome U133 Plus 2.0 Array, as another component to its GeneChip Instrument System, which is used by Affymetrix partners for assay development.

12 Jul 2011

IGR, IPSEN sign 3 year medical oncology agreement

IPSEN, a global biopharmaceutical company represented by Claude Bertrand, Executive Vice President, R&D and Chief Scientific Officer, and Institut de cancérologie Gustave Roussy, a leading international cancer center represented by Professor Alexander Eggermont, General Director, today announced the signature of a partnership in the area of medical oncology to leverage the combined expertises of their respective R&D teams.

12 Jul 2011

Specific miRNAs play a key role in melanoma metastasis

Researchers at the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, identified for the first time the key role specific microRNAs play in melanoma metastasis to simultaneously cause cancer cells to invade and immunosuppress the human body's ability to fight abnormal cells.

12 Jul 2011

Alnylam seeks CTA clearance to initiate ALN-PCS Phase I clinical trial for severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has filed a Clinical Trial Application (CTA) with the Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase I clinical trial with ALN-PCS, an RNAi therapeutic for the treatment of severe hypercholesterolemia.

11 Jul 2011

Merck Serono announces recipients of second Grant for Fertility Innovation

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, today announces the recipients of its second Grant for Fertility Innovation.

8 Jul 2011

Allegro completes $5.4M Series A extension financing

Allegro Diagnostics today announced that it has closed a $5.4M Series A extension financing. The company's existing venture investors, Kodiak Venture Partners and Catalyst Health Ventures, participated in the round.

8 Jul 2011

Understanding glioblastoma at the genetic, molecular level

Glioblastoma is the most common and most lethal form of brain tumor in people. Research published in the International Journal of Computational Biology and Drug Design offers a novel way to determine what biological functions go awry when the tumor first begins to form.

7 Jul 2011