Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

National Cancer Institute awards grant to Receptor Logic for breast cancer research

Receptor Logic, Inc. announced today receipt of a Phase I Small Business Technology Transfer (STTR) Grant from the National Cancer Institute. The grant, entitled “Therapeutic Effectiveness of T-Cell Receptor mimic (TCRm™) Antibodies in Breast Cancer Treatment” will accelerate Investigational New Drug Application enabling studies surrounding lead candidate TCRm antibodies.

3 Sep 2009

Thermo Fisher Scientific to acquire B.R.A.H.M.S. for $470 million

Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science, has signed a definitive agreement to acquire B.R.A.H.M.S. AG for €330 million (approximately $470 million USD). B.R.A.H.M.S. is a leading provider of specialty in-vitro diagnostic tests based on its patented biomarkers for sepsis, cardiovascular and pulmonary diseases, as well as intensive care treatments and prenatal screening.

From Thermo Fisher Scientific Inc. 3 Sep 2009

Annexin-Vivo 750 imaging agent for measuring cell death in vivo

VisEn Medical Inc., a leader in fluorescence in vivo imaging from research through medicine, announced today the commercial launch of its new Annexin-Vivo 750 imaging agent for measuring and monitoring apoptosis and cell death in vivo.

2 Sep 2009

Pacific Biometrics enters into a Loan and Security Agreement to raise $4 million

Pacific Biometrics, Inc. (OTC Bulletin Board: PBME), a leading provider of specialized reference laboratory and contract research services, today announced the Company's entry into a Loan and Security Agreement with Terry M. Giles, providing for a $4 million loan (the "Loan") to the Company.

2 Sep 2009

Immediate catheterization not always better for ACS patients

For some patients with acute coronary syndromes, the strategy of immediate intervention at a medical center does not appear to result in differences in outcomes in comparison with an intervention performed the next working day, according to a study in the September 2 issue of JAMA.

1 Sep 2009

Intrexon purchases assets and operations of Avalon Pharmaceutical

Intrexon Corporation, a privately held life sciences company focused on modular DNA control systems for biotherapeutics and other industry sectors, today announced the purchase of assets and operations of Avalon Pharmaceutical, Inc., a wholly-owned subsidiary of Clinical Data, Inc.

1 Sep 2009

Clinical Data raises funds by selling certain assests to Intrexon Corporation

Clinical Data, Inc. (NASDAQ: CLDA) today announced the sale of certain assets to Intrexon Corporation, a transaction that is consistent with the Company’s ongoing plan to focus resources on its valuable late-stage and preclinical drug programs.

1 Sep 2009

Fifth annual Pathology Visions conference to showcase digital pathology technology and its healthcare applications

The newly formed Digital Pathology Association (DPA), a non-profit organization committed to the advancement of digital pathology applications in healthcare, invites interested pathology professionals to join them for the fifth annual Pathology Visions conference, to be held September 13-15 in San Diego, CA, at the Marriott Hotel and Marina.

31 Aug 2009

Celladon announces completion of patient enrollment for Phase 2 CUPID clinical trial

Celladon Corporation and Momentum Research, Inc. today announced completion of enrollment of the phase 2 double-blind portion of the Calcium Up-regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID) trial. Momentum Research is Celladon’s consulting and management organization with clinical expertise in the development of cardiovascular products and trials.

31 Aug 2009

Two human biomarker assays that play a key role in the early detection of kidney damage provide assistance in drug development

Geneuity Clinical Research Services announces the recent validation and use in clinical trials of two human biomarker assays that play a key role in the early detection of kidney damage.

29 Aug 2009

Champions Biotechnology reports higher year-on-year operating revenues for fiscal year 2009

Champions Biotechnology, Inc. (OTC Bulletin Board: CSBR), a company engaged in the development of advanced preclinical platforms and tumor specific data to enhance the value of oncology drugs, today announced its financial results for the fiscal year ended April 30, 2009. Full details of the Company's financial results are available in the Company's Form 10-K available at www.championsbiotechnology.com.

28 Aug 2009

Research to be conducted on bacterial microbes in space to discover new medicines

Along with supply and equipment cargo bound for the International Space Station, Space Shuttle Discovery STS-128 will carry an additional scientific payload being conducted by Austin-based Astrogenetix, the first commercial space company to use microgravity to discover the foundation of new medicines.

25 Aug 2009

Elevated levels of GLI1 protein linked to unfavorable prognosis and progressive stages in human breast cancer

Elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein in human breast cancer are associated with unfavorable prognosis and progressive stages of disease. Researchers writing in the open access journal BMC Cancer found increased expression of GLI1 in samples taken from more advanced and less survivable tumors.

25 Aug 2009

SQI Diagnostics continues discussions with the FDA to market it's SQiDworks Diagnostics Platform in the US

SQI Diagnostics Inc. (TSX-V: SQD), a medical systems automation company focused on evolving laboratory-based biomarker testing, today announced its financial and operational results for the third quarter ended June 30, 2009.

24 Aug 2009

Ocimum Biosolutions finds place in third annual Inc. 5000 list

Ocimum Biosolutions, a leading integrated life sciences solutions company, has been listed in the third annual Inc. 5000, an exclusive ranking of the America’s fastest-growing private companies. The list represents the most comprehensive look at the most important segment of the economy—America’s independent-minded entrepreneurs.

24 Aug 2009

Discovery of genetic biomarkers enable targeted personalised medication for Colorectal cancer

Colorectal cancer (CRC) is the second leading cause of cancer-related death in the Western world. Fortunately physicians today have an abundance of drug therapies available to improve survival length for more advanced cancer patients. Now the discovery of genetic biomarkers relevant to CRC means that targeted personalised medication is increasingly common.

24 Aug 2009

Genway Clinical Laboratory offers ELISA-based test that detects tumor markers in blood serum

GenWay Clinical Laboratory, a US-based diagnostic company with CLIA certification, has validated a general tumor marker test in their laboratory and now offers this testing service. This is an ELISA-based assay which simply requires a small blood sample from the patient in order to quantify the amount of the tumor marker in their serum.

24 Aug 2009

Biomarker News and Research

Further Reading

National Cancer Institute awards grant to Receptor Logic for breast cancer research

Thermo Fisher Scientific to acquire B.R.A.H.M.S. for $470 million

Annexin-Vivo 750 imaging agent for measuring cell death in vivo

Pacific Biometrics enters into a Loan and Security Agreement to raise $4 million

Immediate catheterization not always better for ACS patients

Intrexon purchases assets and operations of Avalon Pharmaceutical

Clinical Data raises funds by selling certain assests to Intrexon Corporation

Fifth annual Pathology Visions conference to showcase digital pathology technology and its healthcare applications

Celladon announces completion of patient enrollment for Phase 2 CUPID clinical trial

Two human biomarker assays that play a key role in the early detection of kidney damage provide assistance in drug development

Champions Biotechnology reports higher year-on-year operating revenues for fiscal year 2009

Research to be conducted on bacterial microbes in space to discover new medicines

Elevated levels of GLI1 protein linked to unfavorable prognosis and progressive stages in human breast cancer

SQI Diagnostics continues discussions with the FDA to market it's SQiDworks Diagnostics Platform in the US

Ocimum Biosolutions finds place in third annual Inc. 5000 list

Discovery of genetic biomarkers enable targeted personalised medication for Colorectal cancer

Genway Clinical Laboratory offers ELISA-based test that detects tumor markers in blood serum

Researchers find connection between eye disease and arginase

New software programs improve the cancer biomarker identification process

Prion found to be a biomarker for pancreatic cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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