Biomedicine News and Research

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AI model boosts cancer gene prediction and patient prognosis

The artificial intelligence (AI) model GPT-4, known from its application in ChatGPT, shows impressive capabilities in biomedical research and can be used in many ways for simulations. A simulator developed at MedUni Vienna and based on GPT-4 shows increased accuracy in classifying the importance of genes in cancer cells, as well as in the prognosis of cancer patients. The results of the study were published in the journal Computers in Biology and Medicine.

12 Jul 2024

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy treatments.

11 Jul 2024

Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Maternal morbidity and pregnancy risks higher for gestational carriers

Gestational carriers, also known as surrogates, experience an elevated risk of severe maternal morbidity and adverse pregnancy outcomes compared to women who conceive naturally or through in vitro fertilization (IVF), according to new research presented today at the ESHRE 40th Annual Meeting in Amsterdam.

8 Jul 2024

Novel compound amplifies naloxone's power to reverse overdoses

In a Stanford Medicine-led study, researchers combed through billions of compounds to find one that could enhance naloxone’s ability to fend off more potent opioids, with promising results in mice.

4 Jul 2024

Study reveals new mechanisms behind severe COVID-19 in obese individuals without diabetes

Already at the beginning of the COVID-19 pandemic, a group of Brazilian researchers pioneered in showing why SARS-CoV-2 infection tends to be more severe in diabetic patients.

2 Jul 2024

Researchers develop advanced method to analyze liquid biopsies of DNA fragments in the blood

Oncologists use biopsy and imaging techniques to diagnose and monitor tumor diseases and assess treatment success.

1 Jul 2024

Enhancing viral therapy for resistant cancers with a metabolite-drug

When a cancer cell doesn't respond to traditional therapies, doctors may turn to a sort of viral biological warfare, by deploying 'troops' in the form of viral agents that are specifically engineered to target and eliminate cancer cells.

28 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

AI technology offers hope for faster stroke detection

Strokes, which affect millions of people globally, occur when the blood supply to part of the brain is interrupted or reduced, which prevent brain tissue from getting oxygen and nutrients. A few minutes of delay can result in permanent damage to the brain cells.

18 Jun 2024

Stanford study identifies six depression biotypes for personalized treatment

In the not-too-distant future, a screening assessment for depression could include a quick brain scan to identify the best treatment.

17 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy -; a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers -; is low, despite a Food and Drug Administration warning.

12 Jun 2024

New omega-3 therapy shows promise in treating newborn brain injuries

A novel therapeutic approach for neonatal hypoxic-ischemic (HI) brain injury.

11 Jun 2024

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

In a clinical trial conducted by Stanford Medicine investigators and their colleagues, a 15-day course of Paxlovid -; an antiviral drug combination targeting SARS-CoV-2, the virus that causes COVID-19 -; proved safe as an extended-duration treatment but didn't lessen select symptoms of the syndrome known as long COVID: the persistence, or reappearance, of COVID-related symptoms three months or more after an initial COVID-19 infection.

7 Jun 2024

Innovative therapeutic strategies for combating type 2 diabetes

One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels.

7 Jun 2024

Injectable fish oil emulsion reduces brain damage in newborn rodents

An injectable emulsion containing two omega-3 fatty acids found in fish oil markedly reduced brain damage in newborn rodents after a disruption in the flow of oxygen to the brain near birth, a study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

6 Jun 2024