Bleeding Disorder News and Research

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Prophylaxis effective at preventing joint bleeds and preserving joint function and structure in young boys with hemophilia A

According to a new landmark study published in The New England Journal of Medicine, infusions of clotting factor VIII used preventively can significantly reduce the risk of developing joint damage associated with joint bleeding in young children with hemophilia A.

9 Aug 2007

FDA approves Norditropin for short stature in children with Noonan syndrome

Novo Nordisk has announced that Norditropin (somatropin[rDNA origin] injection) received U.S. Food and Drug Administration (FDA) approval for the treatment of short stature in children with Noonan syndrome.

3 Jun 2007

FDA approves new treatment for von Willebrand disease

The U.S. Food and Drug Administration (FDA) has approved Humate-P (Antihemophilic Factor/von Willebrand Factor Complex) for the prevention of excessive bleeding during and after surgery in certain patients with mild to moderate and severe von Willebrand disease (vWD).

30 Apr 2007

Apolipoprotein C1 protein linked to elevated BMI in people of American Indian and Mexican ancestry

University of Minnesota researchers have discovered a variant of a common blood protein, apolipoprotein C1, in people of American Indian and Mexican ancestry that is linked to elevated body mass index (BMI), obesity and Type 2 diabetes.

22 Feb 2007

Alphanate approved to treat Von Willebrand disease

The U.S. Food and Drug Administration (FDA) has announced the approval of Antihemophilic Factor/von Willebrand Factor Complex (Human), Alphanate.

4 Feb 2007

Potential permanent genetic cure for hemophilia A

A discovery by Medical College of Wisconsin and BloodCenter of Wisconsin researchers in Milwaukee may be a key to a permanent genetic cure for hemophilia A patients, including a subset who do not respond to conventional blood transfusions.

3 Jul 2006

Costly IVIg could be replaced with synthetic blood product

Patients suffering from a life-threatening bleeding disorder are closer to having access to a more effective treatment.

1 Jun 2006

Ancient DNA helps unearth potential hemophilia therapy

A cut can be life-threatening for people with hemophilia, whose bodies don't produce enough of a protein that prevents prolonged bleeding.

1 Mar 2006

Emerging infectious agents pose new risks for people with bleeding disorders

An international team of scientists, including a hematologist from Thomas Jefferson University in Philadelphia, has concluded that people with bleeding disorders such as hemophilia remain at risk from emerging infectious agents in plasma and blood transfusions. For this reason, recombinant therapies, that is, those produced in the laboratory, must always be an option

16 Feb 2006

Gene therapy advance shows potential for developing improved treatment for hemophilia

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people.

22 Aug 2005

Lack of a blood clotting protein may protect against clogged arteries

Reporting in the July 18 issue of The Journal of Experimental Medicine, a group of scientists in Wurzburg, Germany show that the lack of a blood clotting protein may protect against clogged arteries with no risk of excessive bleeding.

11 Jul 2005

Experimental drug therapy could open new window for treatment of deadly stroke

A new type of drug therapy that is currently being tested in Canada could significantly reduce the death rate caused by the deadliest form of stroke. According to the Canadian Heart and Stroke Foundation, new developments in stroke research make it more important than ever that Canadians recognize and react to the warning signs of stroke.

9 Jun 2005

Use of a common type of antidepressant may increase gastrointestinal (GI) bleeding

In fact, the study suggests that the increase is similar to that associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs, known as pain relievers). DDW is the largest international gathering of physicians, academics and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

17 May 2005

Herbal remedies and arthritis drugs can be a potentially dangerous mix

Herbal remedies and arthritis drugs can be a potentially dangerous mix, but it's not only patients who are ill informed about the risks, healthcare professionals are too, suggests a survey, reported in the Annals of the Rheumatic Diseases.

19 Apr 2005

Mutations in the HFE gene directly associated with chronic joint disease

Mutations in the HFE gene, which is involved in iron regulation, seem to be directly associated with chronic joint disease (or haemophilic arthropathy) among haemophilic patients, claim a team of Portuguese scientists in the April issue of the journal Blood.

4 Apr 2005

Discovery may have implications for the treatment of hemophilia A and B

University of North Carolina at Chapel Hill researchers have made a discovery that may have implications for the treatment of liver-based genetic defects such as hemophilia A and B in humans.

15 Feb 2005

Potential new therapies for cancer and bleeding disorders

Lexicon Genetics announced today that it has advanced two of its drug discovery programs into preclinical development in preparation for investigational new drug (IND) applications.

10 Jan 2005

First assessment tool to evaluate Quebec Platelet Disorder (QPD)

Researchers at McMaster University have developed the first assessment tool of its kind for evaluating risks faced by Canadians suffering from a rare and often fatal bleeding disorder.

22 Dec 2004

Aspirin might well be considered the top utility player in the medicine cabinet

This cheap over-the-counter drug can be used not only for fever, pain and arthritis, but to prevent heart attack, stroke or angina. It also may reduce the risk of colorectal cancer. Yet aspirin also has side effects worth considering, and its very accessibility may hamper its use.

8 Oct 2004