Bleeding Disorder News and Research

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Age plays a critical role in the diagnosis of von Willebrand disease, study reveals

New research by RCSI University of Medicine and Health Sciences published in Blood journal has revealed that the age at which individuals are tested for von Willebrand disease (VWD), a common bleeding disorder, significantly affects their diagnosis.

8 Jan 2024

Menstrual discs hold the most blood, may be best for heavy flow

Amid widely differing capacities of available menstrual hygiene products, a menstrual disc-;similar in shape to a diaphragm-;may be best for dealing with heavy monthly blood flow as well as indicating excessive blood loss, suggests research published online in the journal BMJ Sexual & Reproductive Health.

7 Aug 2023

Monthly prophylactic fitusiran injections effective in reducing bleeds in patients with hemophilia A or B

Monthly prophylactic injections of fitusiran are effective in reducing bleeds in patients with hemophilia A or B, according to randomized controlled trials publishing simultaneously in The Lancet and The Lancet Haematology journals.

30 Mar 2023

Risks and benefits of recently approved Alzheimer’s drug

The U.S. Food and Drug Administration (FDA) recently granted approval to Lecanemab, the first Alzheimer's disease treatment to win approval since the largely failed rollout of Aduhelm two years ago.

13 Jan 2023

Liver cancer study could help improve the safety of certain gene therapies for hemophilia

Research led by Randal J. Kaufman, Ph.D., has found that misfolded proteins in liver cells contribute to the development of liver cancer, shedding new light on the mysterious origins of one of the world's deadliest diseases.

7 Dec 2022

What does the future look like for bleeding disorders?

In this interview, we speak to Assad Haffar, the Medical and Humanitarian Aid Director at the World Federation of Hemophilia (WFH).

23 Nov 2021

New trial demonstrates stable coagulation factor VIII in hemophilia A patients after gene therapy

A novel gene therapy for hemophilia A led to sustained expression of the clotting factor those patients lack, resulting in a reduction – or in some cases complete elimination – of painful and potentially life-threatening bleeding events, according to a new study led by researchers at Children's Hospital of Philadelphia.

18 Nov 2021

New research finds disturbing lack of crucial blood cancer medication

New research in the November 2021 issue of JNCCN-;Journal of the National Comprehensive Cancer Network finds fewer than one-third of hospitals had immediate availability of a crucial blood cancer medication called all-trans retinoic acid (ATRA).

16 Nov 2021

Teen’s mysterious condition spurs the opening of Childhood Interstitial Lung Disease Clinic

Thirteen-year-old Gregory Rhoden's condition has been a mystery his entire life. He was born prematurely and his lungs seemed underdeveloped.

7 Oct 2021

New technology can pave the way for development of long-acting drugs

The technology, consisting of a designed variant of a natural occurring protein called super albumin, can pave the way for the development of long-acting drugs. This can have major implications for individuals suffering from hemophilia.

21 Jul 2021

Why we may never know whether the $56,000-a-year Alzheimer’s drug actually works

The Food and Drug Administration's approval in June of a drug purporting to slow the progression of Alzheimer's disease was widely celebrated, but it also touched off alarms.

12 Jul 2021

New insights on how certain blood types may predispose to diseases

People with certain blood types are more likely to have blood clots or bleeding conditions, kidney stones, or pregnancy-induced hypertension, suggests a study published today in eLife.

27 Apr 2021

Immune tolerance in hemophilia can be modulated by B cell activating factor

A group of scientists have just made a key discovery that could prevent and eradicate immune responses that lead to treatment failure in about one-third of people with severe hemophilia A.

20 Apr 2021

CHOP researchers identify key target responsible for treatment failure in patients with hemophilia A

Researchers at Children's Hospital of Philadelphia have identified a key target that may be responsible for treatment failure in about 30% of patients with hemophilia A.

15 Apr 2021

MCRI specialists create Australia's and New Zealand's first set of child head injury guidelines

Australia's and New Zealand's first set of clinical guidelines for children's head injuries has been created by a network of specialists based at the Murdoch Children's Research Institute.

2 Feb 2021

New clinical practice guidelines on diagnosis, management of von Willebrand Disease

The American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), National Hemophilia Foundation (NHF), and World Federation of Hemophilia (WFH) have developed joint clinical practice guidelines on the diagnosis and management of von Willebrand Disease (VWD), the world's most common inherited bleeding disorder. The guidelines were published today in Blood Advances.

13 Jan 2021

Bleeding disorder linked to poor clinical outcomes in COVID-19 patients

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the pathogen responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic. Approximately 20-55% of hospitalized COVID-19 patients are reported to have deranged hemostatic laboratory parameters, which suggests coagulopathy.

12 Jan 2021

Endothelial cells resistant to SARS-CoV-2 infection

A team of scientists from Imperial College London has conducted a series of in vitro studies to investigate the susceptibility of endothelial cells to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the causative pathogen of coronavirus disease 2019 (COVID-19).

10 Nov 2020

Providing personalized care for bleeding disorders

An interview with Dr. Carmen Escuriola-Ettingshausen MD, Mörfelden-Walldorf, Germany on providing personalized care for bleeding disorders.

From Takeda 21 Sep 2020

Providing personalized care for bleeding disorders

An interview with Dr. Carmen Escuriola-Ettingshausen MD, Mörfelden-Walldorf, Germany on providing personalized care for bleeding disorders.

From Takeda 21 Sep 2020

Bleeding Disorder News and Research

Age plays a critical role in the diagnosis of von Willebrand disease, study reveals

Menstrual discs hold the most blood, may be best for heavy flow

Monthly prophylactic fitusiran injections effective in reducing bleeds in patients with hemophilia A or B

Risks and benefits of recently approved Alzheimer’s drug

Liver cancer study could help improve the safety of certain gene therapies for hemophilia

What does the future look like for bleeding disorders?

New trial demonstrates stable coagulation factor VIII in hemophilia A patients after gene therapy

New research finds disturbing lack of crucial blood cancer medication

Teen’s mysterious condition spurs the opening of Childhood Interstitial Lung Disease Clinic

New technology can pave the way for development of long-acting drugs

Why we may never know whether the $56,000-a-year Alzheimer’s drug actually works

New insights on how certain blood types may predispose to diseases

Immune tolerance in hemophilia can be modulated by B cell activating factor

CHOP researchers identify key target responsible for treatment failure in patients with hemophilia A

MCRI specialists create Australia's and New Zealand's first set of child head injury guidelines

New clinical practice guidelines on diagnosis, management of von Willebrand Disease

Bleeding disorder linked to poor clinical outcomes in COVID-19 patients

Endothelial cells resistant to SARS-CoV-2 infection

Providing personalized care for bleeding disorders

Providing personalized care for bleeding disorders

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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