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Investigators provide overview of role of dopamine in modulating the immune system

Dopamine is a neurotransmitter that is associated with emotions, movement, and the brain's pleasure and reward system. In the current issue of Advances in Neuroimmune Biology, investigators provide a broad overview of the direct and indirect role of dopamine in modulating the immune system and discuss how recent research has opened up new possibilities for treating diseases such as Parkinson's and Alzheimer's disease, schizophrenia, multiple sclerosis or even the autoimmune disorders.

11 Oct 2012

Tomatoes every day may keep stroke at bay

Regular consumption of tomatoes and other lycopene-rich fruits and vegetables may help reduce a man’s risk for stroke, suggest study findings.

11 Oct 2012

Antioxidant defense reduced in schizophrenia, bipolar disorder

Results from a Tunisian study suggest that the antioxidant defense system is altered in patients with schizophrenia and bipolar disorder.

11 Oct 2012

Amarantus acquires option to license LymPro Alzheimer's diagnostic blood test from MDx

Amarantus BioSciences, Inc., a biotechnology company developing new treatments and diagnostics for Parkinson's disease and Traumatic Brain Injury centred on its proprietary anti-apoptotis therapeutic protein MANF, today announced that it has acquired an exclusive option to license the LymPro Alzheimer's Diagnostic Blood Test from Memory Dx, LLC (MDx), formerly known as Provista Life Sciences, LLC.

11 Oct 2012

Inpeco, Precise Biometrics partner to deploy Precise Match-on-Card technology

Precise Biometrics announces today that they have partnered with the Inpeco Group for a 6-month contract, to deploy Precise Match-on-Card technology to the Inpeco Group System.

11 Oct 2012

Novel neuroimaging technique reveals evidence of cocaine-induced cerebral microischemia

Researchers from the Department of Biomedical Engineering at Stony Brook University have developed a high-resolution, 3D optical Doppler imaging tomography technique that captures the effects of cocaine restricting the blood supply in vessels - including small capillaries - of the brain.

11 Oct 2012

UCI neuro-oncologist to lead DCVax Phase II trial in glioblastoma multiforme

UC Irvine doctors are enrolling patients with the deadly brain tumor glioblastoma multiforme in a clinical trial of a vaccine that may prevent the cancer's return or spread after surgery.

11 Oct 2012

S100A1 protein critical for endothelial cell function in ischemic angiogenesis

Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published online October 9 in Circulation Research from researchers at the Center for Translational Medicine at Thomas Jefferson University.

11 Oct 2012

Researchers develop interference therapies to knock down gene that drives MCL

Three thousand new cases of Mantle Cell Lymphoma (MCL), a form of blood cancer, appear in the United States each year. With a median survival span of only five to seven years, according to the Leukemia and Lymphoma Society, this disease is devastating, and new therapies are sorely needed.

From Integrated DNA Technologies 11 Oct 2012

Transplanted neural stem cells able to produce new myelin in children with PMD

A Phase I clinical trial led by investigators from the University of California, San Francisco and sponsored by Stem Cells Inc., showed that neural stem cells successfully engrafted into the brains of patients and appear to have produced myelin.

11 Oct 2012

Women respond much better than men to treatment of CFL with rituximab

Women respond much better than men to the treatment of chronic follicular lymphoma with a monoclonal antibody that targets CD20 (rituximab). These are the findings of a multi-centre, Austria-wide study by the Arbeitsgemeinschaft medikamentöse Tumortherapie (AGMT) carried out under the supervision of the University Department of Internal Medicine I and study leader Ulrich Jäger, which has now been published in the highly respected journal "Haematologica".

11 Oct 2012

New research lists cell stiffness as possible biomarker for metastatic ovarian cancer

New Georgia Tech research shows that cell stiffness could be a valuable clue for doctors as they search for and treat cancerous cells before they're able to spread. The findings, which are published in the journal PLoS One, found that highly metastatic ovarian cancer cells are several times softer than less metastatic ovarian cancer cells.

11 Oct 2012

Leading scientists select first drugs to be evaluated in Alzheimer's clinical study

Leading scientists have selected the first drugs to be evaluated in a worldwide clinical study to determine whether they can prevent Alzheimer's disease.

11 Oct 2012

Clear link between neurotensin and CVD, type 2 diabetes and breast cancer

"It was surprising to find such a clear link to the risk of type 2 diabetes and cardiovascular disease as well as to breast cancer. Obesity is a common risk factor for all three conditions, but the connection with neurotensin is not explained by obesity or other known risk factors", says Professor Olle Melander from the Department of Clinical Sciences at Lund University, who is also a consultant at Sk-ne University Hospital.

11 Oct 2012

Final results from Covidien’s DEFINITIVE LE study on peripheral arterial disease

Covidien, a leading global provider of healthcare products, today announced final 12-month results from its DEFINITIVE LE (Determination of Effectiveness of SilverHawk / TurboHawk Peripheral Plaque Excision Systems for the Treatment of Infrainguinal Vessels/Lower Extremities) study.

11 Oct 2012

New drug candidate improves cognitive function of rats with Alzheimer's-like mental impairment

Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment.

11 Oct 2012

Fibulin-3 protein may help identify mesothelioma in early stages

Researchers at NYU School of Medicine have discovered the protein product of a little-known gene may one day prove useful in identifying and monitoring the development of mesothelioma in early stages, when aggressive treatment can have an impact on the progression of disease and patient prognosis.

11 Oct 2012

Six-gene signature can predict survival in men with aggressive prostate cancer

Researchers from Mount Sinai School of Medicine have identified a six-gene signature that can be used in a test to predict survival in men with aggressive prostate cancer, according to new research published in the October issue of The Lancet Oncology.

11 Oct 2012

Testosterone fosters social behavior in men

The hormone testosterone stands for typically male attributes - it fosters the forming of the sexual characteristics, increases libido and muscle building. Women also have this sex hormone, but to a much lesser extent.

11 Oct 2012

Ischemic preconditioning tested in stroke patients

Inducing repeated brief ischemia in the arms may reduce the rate of recurrent stroke in patients with symptomatic intracranial arterial stenosis, a small clinical study shows.

10 Oct 2012