Blood Sugar News and Research

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Blood sugar concentration, or glucose level, refers to the amount of glucose present in the blood of a human or animal. Normally, in mammals the blood glucose level is maintained at a reference range between about 3.6 and 5.8 mM (mmol/l). It is tightly regulated as a part of metabolic homeostasis.

DARA's KRN5500 meets primary end-points in Phase II study for chemotherapy-induced neuropathic pain

Thanks to greater awareness, earlier detection and improving therapeutic agents, people with cancer are living longer than ever before. One of the consequences of living longer is the symptom burden of cancer survivorship, which may have a substantial impact on quality of life for many survivors. One such burden is the pain syndromes resulting from cancer treatments.

17 Sep 2011

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

Two newer drugs used to treat Type 2 diabetes could be linked to a significantly increased risk of developing pancreatitis and pancreatic cancer, and one could also be linked to an increased risk of thyroid cancer, according to a new UCLA study.

17 Sep 2011

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced results from an investigational Phase 3b clinical study in which the addition of ONGLYZA (saxagliptin) 5 mg to ongoing insulin therapy (with or without metformin) maintained reductions of blood sugar levels (glycosylated hemoglobin levels, or HbA1c) in adult patients with type 2 diabetes compared to the addition of placebo (with or without metformin) from 24 to 52 weeks.

16 Sep 2011

Lack of communication between diabetes patients and physicians around hypoglycaemia: Survey

New multinational survey data released to coincide with the European Association for the Study of Diabetes (EASD) 47th Annual Meeting has revealed a lack of communication between type 2 diabetes patients and physicians around hypoglycaemia.

15 Sep 2011

Novo Nordisk's insulin degludec reduces blood sugar in patients with type 2 diabetes

Ultra-long-acting insulin degludec, an investigational basal insulin being developed by Novo Nordisk, showed significant blood sugar reductions in patients with type 2 diabetes.

From Novo Nordisk 15 Sep 2011

Uterine stem cells could help treat diabetes

Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published in the journal Molecular Therapy.

15 Sep 2011

Novo Nordisk announces free diabetes educational e-book series

Today, Novo Nordisk, a world leader in diabetes care, launched a free 5-volume diabetes educational e-book series, designed to help patients work with their health care team to better manage their diabetes. The e-book series is part of Cornerstones4Care™, an innovative patient support program that provides highly customizable diabetes information through the comprehensive interactive website www.Cornerstones4Care.com.

From Novo Nordisk 14 Sep 2011

Lucentis receives Health Canada approval to treat vision loss from DME

Health Canada has approved Lucentis (ranibizumab) as a treatment for vision loss resulting from diabetic macular edema, one of the major causes of adult vision loss and an important complication of the growing epidemic of diabetes.

14 Sep 2011

Survey highlights need for better diabetes treatment guidelines

A survey of federally funded diabetes prevention and control programs in 57 U.S. states and territories has highlighted the need for better diabetes treatment guidelines that are specifically adapted to different populations. Such guidelines do not currently exist.

14 Sep 2011

Health Canada approves Afinitor for treatment of brain tumours caused by TSC in children

Families with children suffering from brain tumours caused by an uncommon genetic disorder known as Tuberous Sclerosis Complex (TSC) have new hope with Health Canada's recent conditional approval of a new therapeutic use for the drug Afinitor (everolimus). Afinitor is the first drug therapy approved in Canada for the treatment of brain tumours caused by TSC in patients three years of age and older.

14 Sep 2011

Lantus initiation may help limit weight gain in type 2 diabetes patients

Sanofi announced today data that demonstrates that initiating Lantus® (insulin glargine [rDNA origin] injection) in type 2 diabetes patients leads to better glycemic control and comparable and modest weight gain versus a comparator group consisting of other insulins, oral antidiabetics and dietary changes.

12 Sep 2011

Researchers create powerful anti-diabetic prototype drugs with lesser side effects

Researchers from Dana-Farber Cancer Institute in Boston and the Scripps Research Institute in Jupiter, Fla., report they have created prototype drugs having powerful anti-diabetic effects, yet apparently free - at least in mice - of dangerous side effects plaguing some current diabetes medications.

9 Sep 2011

InnoCentive, JDRF announce $100,000 Challenge to uncover solutions for insulin-dependent diabetes

The Juvenile Diabetes Research Foundation (JDRF), the worldwide leader for research to cure, treat, and prevent type 1 diabetes, and InnoCentive, Inc., the pioneer in open innovation and crowdsourcing, today announced a $100,000 Challenge calling for innovative ways to approach the discovery and development of a glucose-responsive insulin drug as a means to treat insulin-dependent diabetes.

9 Sep 2011

Lilly, Boehringer Ingelheim to present latest data from diabetes portfolio at 47th EASD meeting

Boehringer Ingelheim and Eli Lilly and Company will present the latest data from their diabetes portfolio at the 47th Annual Meeting of the European Association for the Study of Diabetes (EASD) in Lisbon, Portugal, September 12-16.

8 Sep 2011

Loss of estrogen receptor alpha protein may lead to metabolic syndrome

UCLA researchers demonstrated that loss of a key protein that regulates estrogen and immune activity in the body could lead to aspects of metabolic syndrome, a combination of conditions that can cause Type 2 diabetes, atherosclerosis and cancer. Called estrogen receptor alpha, this protein is critical in regulating immune system activity such as helping cells suppress inflammation and gobble-up debris.

7 Sep 2011

Scientists uncover new ways to stimulate pancreatic beta cell growth

One of the holy grails in diabetes research is to discover molecules that stimulate beta cell growth and to find drugs that target these molecules. Now, JDRF-funded researchers in collaboration with the pharmaceutical company Hoffmann-La Roche, have done both, discovering not only a protein that regulates beta cell growth, but also a chemical compound that stimulates it.

7 Sep 2011

Inflammation boosts activity of two proteins that can normalize blood sugar in diabetics

Increased low-grade inflammation in the body resulting from obesity is widely viewed as contributing to type 2 diabetes. Going against this long-held belief, researchers from Children's Hospital Boston report that two proteins activated by inflammation are actually crucial for maintaining good blood sugar levels - and that boosting the activity of these proteins can normalize blood sugar in severely obese and diabetic mice.

5 Sep 2011

Blood Sugar News and Research

Further Reading

DARA's KRN5500 meets primary end-points in Phase II study for chemotherapy-induced neuropathic pain

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Lack of communication between diabetes patients and physicians around hypoglycaemia: Survey

Novo Nordisk's insulin degludec reduces blood sugar in patients with type 2 diabetes

Uterine stem cells could help treat diabetes

Novo Nordisk announces free diabetes educational e-book series

Lucentis receives Health Canada approval to treat vision loss from DME

Survey highlights need for better diabetes treatment guidelines

Health Canada approves Afinitor for treatment of brain tumours caused by TSC in children

Lantus initiation may help limit weight gain in type 2 diabetes patients

Researchers create powerful anti-diabetic prototype drugs with lesser side effects

InnoCentive, JDRF announce $100,000 Challenge to uncover solutions for insulin-dependent diabetes

Lilly, Boehringer Ingelheim to present latest data from diabetes portfolio at 47th EASD meeting

Loss of estrogen receptor alpha protein may lead to metabolic syndrome

Scientists uncover new ways to stimulate pancreatic beta cell growth

Inflammation boosts activity of two proteins that can normalize blood sugar in diabetics

Study describes new class of anti-diabetic compound that targets unique molecular switch

Wis. patients getting tested for HIV after misuse of equipment

Investments in EHRs could reap major benefits in better patient care, health outcomes

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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