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Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research delves into the complex roles of neutrophils in inflammatory bowel disease (IBD), exploring their diverse functions and interactions with the gut microbiota and emphasizing the need for targeted therapies based on these insights.

27 Dec 2023

Common inflammation pathway turns anthrax toxin into killer

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system.

26 Dec 2023

Shedding new light on the evolution of tuberculosis

Recent research suggests that the emergence of tuberculosis infection in human populations dates back tens of thousands of years earlier than previously known cases in the Middle East.

26 Dec 2023

Citrus supplement may ease knee swelling and pain after surgery

For patients undergoing total knee arthroplasty (TKA), treatment with diosmin – a flavonoid supplement derived from citrus fruits –reduced swelling of the knee and leg and some measures of associated pain can be achieved, reports a clinical trial in The Journal of Bone & Joint Surgery.

22 Dec 2023

Spatial profiling predicts recurrence of Hodgkin lymphoma after bone marrow transplant

Cedars-Sinai Cancer investigators have discovered a new way to predict whether a cancer of the immune system will recur in patients treated with a bone marrow transplant.

22 Dec 2023

3D-printed bone: Biomimetic scaffolds offer hope for cranial defect repair

The cranial bone in the human body performs very important functions, such as protecting the brain and enabling the passage of the cranial nerves that are essential to physiological functioning.

22 Dec 2023

‘AGGA’ inventor testifies his dental device was not meant for TMJ or sleep apnea

A Tennessee dentist who has been sued by multiple TMJ and sleep apnea patients over an unproven dental device he invented has said under oath that he never taught dentists to use the device for those ailments — contradicting video footage of him telling dentists how to use it.

22 Dec 2023

Deep flaws in FDA oversight of medical devices, and patient harm, exposed in lawsuits and records

Living with diabetes, Carlton "PeeWee" Gautney Jr. relied on a digital device about the size of a deck of playing cards to pump insulin into his bloodstream.

21 Dec 2023

$Higher doses of topical corticosteroids linked to increased risks of osteoporosis and bone fractures$

Higher doses of topical corticosteroids linked to increased risks of osteoporosis and bone fractures

New research indicates that higher doses of topical corticosteroids, which are commonly used to treat inflammatory skin conditions, are linked with elevated risks of osteoporosis and bone fractures associated with osteoporosis.

20 Dec 2023

Embryonic immune sensor could key to creating patient-derived blood stem cells

A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.

19 Dec 2023

A novel stem cell solution for preventing ischemia-induced amputations

Across the United States, about 2 million people are living with an amputation and another 185,000 amputations occur every year, according to the Amputee Coalition, a Washington DC-based support group.

19 Dec 2023

Biased AI models can trick doctors, study finds

AI models in health care are a double-edged sword, with models improving diagnostic decisions for some demographics, but worsening decisions for others when the model has absorbed biased medical data.

19 Dec 2023

New $3.2 million grant fuels collaborative fight against cancers

Researchers from disparate disciplines located at USC, Cedars-Sinai Medical Center, Children’s Hospital Los Angeles and Stanford University gather to find solutions to cancer through the newly formed Convergent Science Cancer Consortium.

18 Dec 2023

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

Prunes pack a powerful punch against inflammation and bone loss in postmenopausal women

A new study published in The Journal of Nutrition shows daily consumption of prunes may reduce inflammation markers connected to bone signalling pathways and reduce the effects of bone loss among postmenopausal women.

15 Dec 2023

Childhood sedentariness may be a key factor in elevated cholesterol and premature heart disease

Children who are physically inactive may have high cholesterol in early adulthood and subsequent heart health issues in their mid-forties, according to new research published in The Journal of Clinical Endocrinology & Metabolism.

14 Dec 2023

Novel drug combinations could protect snakebite victims from devastating injuries

New drug combinations could protect snakebite victims from the devastating, life-changing injuries caused by toxic venom, promising new research led by Liverpool School of Tropical Medicine suggests.

14 Dec 2023

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

The role of type-2 interferon (IFNγ) in antiviral immunity.

14 Dec 2023

Cola cure? Study sheds light on soda's potential for common holiday medical emergency

Researchers performed a randomized controlled trial (RCT) to evaluate the safety and effectiveness of cola in relieving esophageal meal bolus impaction.

14 Dec 2023

Scientists unlock secret to repairing malnourished children's guts

A clinical trial reported in 2021 and conducted by a team of researchers from Washington University School of Medicine in St. Louis and the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, showed that a newly designed therapeutic food aimed at repairing malnourished children's underdeveloped gut microbiomes was superior to a widely used standard therapeutic food.

13 Dec 2023

Bone News and Research

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Common inflammation pathway turns anthrax toxin into killer

Shedding new light on the evolution of tuberculosis

Citrus supplement may ease knee swelling and pain after surgery

Spatial profiling predicts recurrence of Hodgkin lymphoma after bone marrow transplant

3D-printed bone: Biomimetic scaffolds offer hope for cranial defect repair

‘AGGA’ inventor testifies his dental device was not meant for TMJ or sleep apnea

Deep flaws in FDA oversight of medical devices, and patient harm, exposed in lawsuits and records

Higher doses of topical corticosteroids linked to increased risks of osteoporosis and bone fractures

Embryonic immune sensor could key to creating patient-derived blood stem cells

A novel stem cell solution for preventing ischemia-induced amputations

Biased AI models can trick doctors, study finds

New $3.2 million grant fuels collaborative fight against cancers

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

Prunes pack a powerful punch against inflammation and bone loss in postmenopausal women

Childhood sedentariness may be a key factor in elevated cholesterol and premature heart disease

Novel drug combinations could protect snakebite victims from devastating injuries

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

Cola cure? Study sheds light on soda's potential for common holiday medical emergency

Scientists unlock secret to repairing malnourished children's guts

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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