Bone News and Research

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Researchers to develop new treatment strategy for cancer

Cancer is a difficult disease to treat because it's a personal disease. Each case is unique and based on a combination of environmental and genetic factors. Conventional chemotherapy employs treatment with one or more drugs, assuming that these medicines are able to both "diagnose" and "treat" the affected cells. Many of the side effects experienced by chemotherapy patients are due to the fact that the drugs they are taking aren't selective enough.

7 Sep 2010

Study on bacteria may help to develop treatment method for osteomyelitis

A surface molecule on bacteria that instructs bone cells to die could be the target for new treatments for bone disease, says a scientist speaking at the Society for General Microbiology's autumn meeting today.

7 Sep 2010

Childhood cancer survivors 5 times more likely to get cancer again: Study

According to a new study, children who survive cancer are at a higher risk of cancer later in life or may die early of other cause. The study included almost 900 young cancer survivors treated at Sydney Children's Hospital, from 1972 to 1999, alongside new cancer cases and early deaths. The risk of cancer was five times higher in childhood cancer survivors, the results showed, compared with the overall NSW population, that these survivors were seven and a half times more likely to die early.

5 Sep 2010

MIT develops safer, simpler way to attach phosphorus to organic compounds

Phosphorus, a mineral element found in rocks and bone, is a critical ingredient in fertilizers, pesticides, detergents and other industrial and household chemicals. Once phosphorus is mined from rocks, getting it into these products is hazardous and expensive, and chemists have been trying to streamline the process for decades.

4 Sep 2010

Study suggest PET/CT scanning may offer effective breast cancer detection, spread

About one-third of women diagnosed with early-stage breast cancer will have their cancer travel, or metastasize, to other parts of the body, with the bone being the most common site of initial detectable spread. Controversy continues to surround the question of whether CT and bone scans should be standard in evaluating patients for these metastases, or whether integrated PET/CT scanning might be more effective at detecting breast tumors that have reached nearby bones.

4 Sep 2010

International study to improve treatments for Duchenne muscular dystrophy

A large international study aimed at improving the care of muscular dystrophy patients worldwide is being launched by physicians, physical therapists, and researchers at the University of Rochester Medical Center.

3 Sep 2010

Celgene receives Paragraph IV Certification Letter on submission of ANDA for REVLIMID

Celgene Corporation today announced it has received a Paragraph IV Certification Letter advising that Natco Pharma Limited of Hyderabad, India, submitted an Abbreviated New Drug Application to the U.S. Food and Drug Administration. The application requests authorization to manufacture and market generic versions of REVLIMID (lenalidomide) 5, 10, 15 and 25 mg capsules in the United States.

3 Sep 2010

Cardiogenesis Corporation releases comment on STAR-heart study

Cardiogenesis Corporation, released comments today regarding the STAR-heart study.The STAR-heart study, which was presented at the European Society of Cardiology 2010 Congress in August 2010, reported that the intracoronary injection of autologous stem cells derived from bone marrow is associated with improved hemodynamics and long term survival in the treatment of chronic heart failure.

3 Sep 2010

Gilead Sciences seeks MAA in Europe for fixed-dose combination of Truvada and TMC278 for HIV-1 infection

Gilead Sciences, Inc. today announced that it has submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) for marketing approval for the fixed-dose combination of Truvada® (emtricitabine and tenofovir disoproxil (as fumarate)) and Tibotec Pharmaceuticals' investigational non-nucleoside reverse transcriptase inhibitor TMC278 (rilpivirine (as hydrochloride)) for the treatment of HIV-1 infection in adults.

3 Sep 2010

Researchers identify metabolic property of stem cells to survive in low-oxygen environments

UT Southwestern Medical Center researchers have identified unique metabolic properties that allow a specific type of stem cell in the body to survive and replicate in low-oxygen environments.

3 Sep 2010

Arthroscopic surgery for torn shoulder muscles in elderly patients can reduce pain

Repairing torn shoulder muscles in elderly patients is often discouraged because of fears of complications. But a new study conducted at Rush University Medical Center has shown that minimally invasive, or arthroscopic, surgery can significantly improve pain and function.

3 Sep 2010

Foot and ankle injuries among athletes rise since 2003: Report

Sports-related injuries are part of the game, and as athletes are becoming stronger, faster, and better conditioned, higher-energy injuries are becoming common. Foot and ankle injuries are especially concerning because they are increasing in number and severity and are often misunderstood.

3 Sep 2010

Study finds source of tetracycline from bone analysis of Nubians

A chemical analysis of the bones of ancient Nubians shows that they were regularly consuming tetracycline, most likely in their beer. The finding is the strongest evidence yet that the art of making antibiotics, which officially dates to the discovery of penicillin in 1928, was common practice nearly 2,000 years ago.

3 Sep 2010

Study demonstrates safety of cord blood stem cell transplantation protocol to treat neurological conditions

In a new peer-reviewed article published by the Journal of Translational Medicine, scientists from Beike Biotechnology,China's leading stem cell research and regenerative medicine company, and Medistem, Inc.,reported positive safety data in 114 patients who were treated by doctors at Nanshan Affiliated Hospital of Guangdong Medical College (Shenzhen Nanshan Hospital) in Shenzhen using Beike's proprietary cord blood stem cell transplantation protocol.

3 Sep 2010

FDA approves Ascension Orthopedics' TITAN Modular Total Shoulder System

Ascension Orthopedics, Inc., the world leader in PyroCarbon orthopedic devices, announces FDA approval to market the TITAN™ Modular Total Shoulder System. This newly designed system redefines modularity by providing multiple surgical solutions for shoulder arthroplasty with one implant system.

3 Sep 2010

Japanese plate and screw market to grow to over $170 million by 2014

According to Millennium Research Group (MRG), the global authority on medical technology market intelligence, the Japanese plate and screw market will be driven by strong surgeon acceptance and adoption, driving this market to over $170 million by 2014.

2 Sep 2010

TGen researchers use RNAi-based screening to study Ewing's sarcoma

The first study of Ewing's sarcoma that screened hundreds of genes based on how they affect cell growth has identified two potential anti-cancer drug targets, according to a scientific paper by the Translational Genomics Research Institute published this month in the journal Molecular Cancer.

2 Sep 2010

Cellerant Therapeutics signs contract with BARDA to develop CLT-008 therapy for ARS

Cellerant Therapeutics Inc., a biotechnology company developing novel hematopoietic stem cell-based cellular and antibody therapies for blood disorders and cancer, announced today that it has signed a contract valued at up to $153 million over five years with the Biomedical Advanced Research and Development Authority (BARDA) in the Office of the Assistant Secretary for Preparedness and Response of the Department of Health and Human Services, to develop CLT-008, a cellular therapy for the treatment of Acute Radiation Syndrome (ARS).

2 Sep 2010

Anxiety in school is seasonal and age dependent: Pediatric psychiatrists

With summer fading, anxiety is on the rise for some students anticipating the return of school. But it isn't just the first days of classes that can provoke angst -- anxiety in school is seasonal and age dependent, say pediatric psychiatrists.

2 Sep 2010

Illinois profs receive grant to work with kidney dialysis patients

University of Illinois scientists will learn whether protein supplements and cycling during treatments can help dialysis patients fight cardiovascular disease and retain physical function, thanks to a $2.1 million grant from the National Institutes of Health (NIH).

2 Sep 2010