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Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for this condition.

14 Feb 2023

Active compound from edible mushrooms boosts nerve growth and enhances memory

Researchers from The University of Queensland have discovered the active compound from an edible mushroom that boosts nerve growth and enhances memory.

10 Feb 2023

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

An unexpected discovery made by experts at the Brain Tumor Center at Cincinnati Children's while studying a rare-but-deadly type of brain tumor may also lead to improved treatments for several other forms of cancer that share a common influencing factor called a YAP fusion protein.

2 Feb 2023

Machine learning tool can enhance the inference of complex cell identities

When genes are activated and expressed, they show patterns in cells that are similar in type and function across tissues and organs.

13 Jan 2023

New electrically conductive hydrogel scaffold supports neural cell differentiation

Brain-computer interfaces (BCIs) are a hot topic these days, with companies like Neuralink racing to create devices that connect humans' brains to machines via tiny implanted electrodes.

5 Jan 2023

New insights into how working memory information may be held in mind

Between the time you read the Wi-Fi password off the café's menu board and the time you can get back to your laptop to enter it, you have to hold it in mind.

29 Dec 2022

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to be able to affect the course of this relentless, incurable disease.

26 Dec 2022

First cell-type specific multiomic study of the HIV brain

Researchers identify cell-type-specific differences in HIV integration sites in the brain.

19 Dec 2022

Study implicates a specific type of brain cell as key player underlying the impact of stressors

More than 70% of adults will experience at least one traumatic experience, such as a life-threatening illness or accident, violent assault or natural disaster, in their lifetimes and nearly a third will experience four or more, according to global data.

1 Dec 2022

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

A change in the DNA code (mutation) of a gene that plays a key role in the brain's immune defenses may prevent related cells from clearing away protein-filled clumps, a new study in mice shows.

30 Nov 2022

Removal of cilia from the brain's striatum impairs time perception and judgment, study finds

Researchers at the University of California, Irvine have discovered that removal of cilia from the brain's striatum region impaired time perception and judgment, revealing possible new therapeutic targets for mental and neurological conditions including schizophrenia, Parkinson's and Huntington's diseases, autism spectrum disorder, and Tourette syndrome.

30 Nov 2022

The distinct pathophysiology of ‘SuperAger’ brains

Superagers are adults over the age of 80 who have a superior memory capacity that resembles that of middle-aged adults.

27 Nov 2022

Study provides a key link between the social environment and healthy brains

As people age, maintaining a positive and predictable social environment becomes more and more important. For instance, keeping close ties with friends and family has been identified as one of the key ingredients to healthy aging.

24 Nov 2022

Previously unknown links between genetic factors in ASD identified

In a new study published today in Cell Reports, researchers from the Donald K. Johnson Eye Institute (DKJEI), part of the Krembil Research Institute at University Health Network, have identified previously unknown connections between genetic factors in Autism Spectrum Disorder (ASD).

22 Nov 2022