Brain Disease News and Research

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Vanderbilt's potential schizophrenia treatment enters phase 1 clinical trials

A potential schizophrenia treatment discovered through the Warren Center for Neuroscience Drug Discovery has been cleared by the U.S. Food and Drug Administration for use in phase 1 clinical trials-;the third WCNDD therapeutic to reach that benchmark.

7 Dec 2023

Latest scientific findings provide new insights into heart and stroke health

More than 4,000 abstracts were presented during the American Heart Association's Scientific Sessions 2023 and Resuscitation Science Symposium 2023, held earlier this month in Philadelphia.

28 Nov 2023

Reducing cholesterol esters protects the brain against Alzheimer's-like damage

In Alzheimer's disease and related dementias, cognitive decline is driven by the overaccumulation of a normal brain protein known as tau.

22 Nov 2023

Non-invasive device detects Alzheimer's and Parkinson's biomarkers with high accuracy

An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer's and Parkinson's Diseases.

13 Nov 2023

Depression, anxiety and chronic stress increase risk for heart and brain health complications

The heart and mind are strongly connected, with depression, anxiety and chronic stress all increasing the risk for heart and brain health complications, according to two preliminary studies to be presented at the American Heart Association's Scientific Sessions 2023.

6 Nov 2023

Researchers pioneer a novel treatment for the most common autoimmune encephalitis

Researchers at DZNE and Charité - Universitätsmedizin Berlin have pioneered a novel treatment for the most common autoimmune encephalitis.

3 Nov 2023

Graphene oxide offers a promising new approach to treating Alzheimer's disease

A probable early driver of Alzheimer's disease is the accumulation of molecules called amyloid peptides. These cause cell death, and are commonly found in the brains of Alzheimer’s patients. Researchers at Chalmers University of Technology, have now shown that yeast cells that accumulate these misfolded amyloid peptides can recover after being treated with graphene oxide nanoflakes.

9 Oct 2023

Graphene oxide nanoflakes may help treat Alzheimer's disease

A probable early driver of Alzheimer's disease is the accumulation of molecules called amyloid peptides. These cause cell death, and are commonly found in the brains of Alzheimer's patients.

4 Oct 2023

Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.

19 Sep 2023

Erectile dysfunction can be a sign of undiagnosed diabetes in men under 40

Erectile dysfunction (ED) is more common in older individuals with long-term Type 2 diabetes. However, emerging research at Saint Louis University School of Medicine has found that ED indicates undiagnosed prediabetes and type 2 diabetes in young men under 40.

25 Aug 2023

Parents and clinicians reach consensus on pediatric decision-making

How should others make decisions for pediatric patients? For decades, there has been debate in academic literature about the ethical principles that govern medical decision-making for children.

11 Aug 2023

Machine learning can accurately predict subtypes of Parkinson's disease

Researchers at the Francis Crick Institute and UCL Queen Square Institute of Neurology, working with technology company Faculty AI, have shown that machine learning can accurately predict subtypes of Parkinson's disease using images of patient-derived stem cells.

10 Aug 2023

SLU research finds link between anxiety disorders, benzodiazepine exposure and dementia in seniors

Research from Saint Louis University School of Medicine finds that among patients 65 and older, a diagnosis of anxiety was significantly associated with an increased risk of dementia diagnosis, and benzodiazepine exposure was associated with a 28% increased risk of dementia.

7 Aug 2023

Muscle-building supplement may help protect memory and prevent Alzheimer's disease

The secret to protecting your memory may be a staple of a bodybuilder's diet. RUSH researchers recently discovered that a muscle-building supplement called beta-hydroxy beta-methylbutyrate, also called HMB, may help protect memory, reduce plaques and ultimately help prevent the progression of Alzheimer's disease.

21 Jul 2023

Football players at risk for CTE based on cumulative force of head hits, study shows

For years, researchers studying chronic traumatic encephalopathy, or CTE, believed the primary cause of it was repetitive hits to the head, whether or not those hits caused concussions.

23 Jun 2023

Building resilient brains: strategies for promoting brain health in older adults

Researchers reviewed the overarching theme of brain health from the perspective of aging and preventive care.

21 Jun 2023

Study links astrocytic TDP-43 dysfunction to cognitive decline in dementia: Unlocking potential therapeutic strategies

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20 Apr 2023

Computer-assisted method accurately recognizes the severity of ataxia-related speech disturbances

Researchers at DZNE and the University Hospital Bonn, together with the Berlin-based company PeakProfiling GmbH, have developed a computer-assisted method that recognizes the severity of speech disturbances resulting from ataxia, a brain disease, with great accuracy.

18 Apr 2023

Using brain organoids to test gene therapies for a rare disease in children

Brain tissue grown in a laboratory by University of Queensland researchers will be used to test a treatment for a rare disease in children and help unlock therapies for a range of neurological disorders.

5 Apr 2023

Playing tackle football at an early age increases risk for brain decline later

The degenerative brain disease known as CTE, or chronic traumatic encephalopathy, has become a specter haunting football.

20 Mar 2023