C. Diff News and Research

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Study finds 22% antibiotic failure rate in pneumonia treatment

The new study presented at the 2017 American Thoracic Society International Conference has found that about 22.1%, approximately one in four adults, failed to respond to antibiotics for community-acquired pneumonia (CAP) treatment.

23 May 2017

Study: Antibiotic therapy does not work for nearly one in four adults with community-acquired pneumonia

Approximately one in four (22.1 percent) adults prescribed an antibiotic in an outpatient setting (such as a doctor's office) for community-acquired pneumonia does not respond to treatment, according to a new study presented at the 2017 American Thoracic Society International Conference.

22 May 2017

Case Western Reserve and Q2 Pharma partner to develop antivirulence agents that disarm superbugs

Case Western Reserve University and Q2 Pharma Ltd., an Israeli biopharmaceutical company, have signed a two-year option to license small molecule, antivirulence technology to potentially treat bacterial infections such as methicillin-resistant staphylococcus aureus (MRSA), the first known scientific effort of its kind.

31 Mar 2017

Pill form of C-diff treatment could be effective, easier for patients and physicians, study shows

Frozen and freeze-dried products for Fecal Microbiota Transplantation are nearly as effective as fresh product at treating patients with Clostridium difficile infection, according to researchers at The University of Texas Health Science Center at Houston School of Public Health and Kelsey Research Foundation.

14 Mar 2017

New treatment for C.diff infections reduces recurrences by 40%, study finds

A new treatment for Clostridium difficile (C.diff) infections reduces recurrent infections by nearly 40%, a large study has found.

25 Jan 2017

Preventing C. difficile infections could save thousands of lives and millions of health care dollars

The constant fear of having an embarrassing bathroom accident paralyzed Judy Post. Mental, physical and emotional stress consumed her. She wondered if her life would ever return to normal.

7 Dec 2016

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

It may be possible to safely prevent one of the most common - and costly to treat - infections contracted by hospitalized patients undergoing bone marrow transplantation for the treatment of blood cancers, according to a study from the Abramson Cancer Center at the University of Pennsylvania.

29 Nov 2016

High levels of dietary zinc increase susceptibility to Clostridium difficile infections

Too much dietary zinc increases susceptibility to infection by Clostridium difficile - "C. diff" - the most common cause of hospital-acquired infections.

26 Sep 2016

Ancient remedy to treat severe diarrhea becomes effective therapy for multiple recurrent CDI

Modern medicine is taking a new look at an ancient remedy for severe diarrhea as a novel approach to treat a serious gastrointestinal infection.

22 Sep 2016

Beckman Coulter’s new DxH 500 haematology system installed at University of Chester’s Institute of Medicine

Beckman Coulter has installed the first DxH 500 haematology analyser in the UK at the University of Chester’s Institute of Medicine on the Countess of Chester Health Park.

From Beckman Coulter Diagnostics 20 Sep 2016

Allergy-causing immune cells play life-saving role in deadly C. difficile infection

Researchers at the University of Virginia School of Medicine have identified immune cells vital for protecting us from potentially fatal C. difficile infection. Surprisingly, those cells are often vilified for their role in causing asthma and allergies. But when it comes to C. difficile, they could be the difference in life and death.

29 Jun 2016

New frozen faecal bank increases chances of curing a chronic health condition

A new frozen faecal bank that could save hundreds of lives and dramatically improve the quality of life of many more has been established at a Portsmouth hospital.

20 May 2016

UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

Researchers at University of California, San Diego School of Medicine have received a five-year, $9.5-million award from the National Institute of Allergy and Infectious Diseases at the National Institutes of Health to establish an interdisciplinary center to define the systems biology of antibiotic resistance. The program will be led by Bernhard Palsson, PhD, Distinguished Professor of Bioengineering and Pediatrics, and Victor Nizet, MD, professor of pediatrics and pharmacy.

13 Apr 2016

Discovery takes researchers one step closer to preventing C. diff

Exposure to specific antibiotics is linked to the development of certain strains of antibiotic-resistant C. difficile, one of the fastest growing bacteria superbugs, according to a new study published by Stuart Johnson, MD, of Loyola University Health System, Loyola University Chicago Stritch School of Medicine and the Hines VA Medical Hospital.

5 Feb 2016

Mayo Clinic adds robots to prevent C-diff bacteria

Mayo Clinic has added robots in its fight against Clostridium difficile (C-diff) bacteria. In the U.S., C-diff is one of the most common infections patients can get while receiving care at a health care facility. C-diff can cause a variety of symptoms, including potentially deadly diarrhea. A recent national report shows some progress in reducing C-diff infections; however, more work remains.

20 Jan 2016

Frozen fecal transplantation effective at providing relief to C. diff patients

Frozen fecal transplantation is effective at providing relief to Clostridium difficile (C. diff) patients, according to a new study co-authored by University of Guelph researchers.

18 Jan 2016

Discoveries could lead to development of novel therapies to prevent C. diff infection

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile ("C. diff") -- the leading cause of hospital-acquired diarrhea in the United States.

12 Jan 2016

Common antibiotics can promote C. diff infections by killing off bile acid-altering microbes

New research from North Carolina State University and the University of Michigan finds that bile acids which are altered by bacteria normally living in the large intestine inhibit the growth of Clostridium difficile, or C. diff. C. diff is a harmful bacterium that can cause painful and sometimes fatal infections.

7 Jan 2016

Bacteriophage therapy: an alternative to antibiotics? An interview Professor Clokie

A phage is a virus that infects a bacterium. People often get very confused about what the difference is between a virus and a bacterium. A virus, like a bacterium, is also a microorganism, but unlike bacteria, it needs to have a host to be able to replicate and propagate.

2 Dec 2015

Loyola professor receives prestigious 2015 Marion Spencer Fay Award

Loyola University Chicago Professor Katherine L. Knight, PhD, one of the nation's leading immune system researchers, has received the prestigious 2015 Marion Spencer Fay Award.

20 Nov 2015