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Research may provide the basis for development of a new, extensive immunotherapy for human tumors

Scientists have made significant progress towards understanding how the immune system can be more specifically and efficiently targeted against cancer cells. The research, published in the January issue of Immunity, may provide the basis for development of a new, extensive immunotherapy for human tumors.

26 Jan 2005

AIDS breakthrough - vaccine strengthens the body’s immune system againts HIV

A Hadassah University Medical Center research team has developed a vaccine that significantly strengthens the body’s immune system against the autoimmune sequela of HIV infection, a breakthrough that could dramatically make an impact in the treatment of AIDS patients.

28 Dec 2004

Discovery of key immune system molecules that helps determine how effectively a person resists HIV infection

A team of researchers based partly in South Africa has identified a key set of immune system molecules that helps determine how effectively a person resists infection with human immunodeficiency virus (HIV).

8 Dec 2004

Revlimid clinical data in newly diagnosed multiple myeloma presented

Celgene Corporation announced today that data evaluating clinical results on Revlimid (lenalidomide) as a new therapeutic approach for patients with newly diagnosed multiple myeloma (MM) was presented at the American Society of Hematology 46th Annual Meeting in San Diego.

7 Dec 2004

Low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries

Results of a randomised trial in this week’s issue of THE LANCET highlight how the low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries to help reduce illness and death from opportunistic infections such as pneumonia.

18 Nov 2004

Lag-3 gene dampens immune responses by controlling regulatory T-cell function

The discovery that the Lag-3 gene acts as a brake to prevent immune system responses from running out of control solves a mystery that has puzzled researchers since the gene was discovered 14 years ago.

22 Oct 2004

Research findings will likely aid efforts to develop a vaccine for Leishmania major

Researchers at Washington University School of Medicine in St. Louis and the University of Pennsylvania have found an immune system cell can "remember" a parasite's attack and help the body mount a more effective defense against subsequent invasions by the same parasite.

21 Oct 2004

Highly concentrated solution of chemical messengers could block male to female HIV transmission

Researchers in the U.S have shown that it may be possible to block the transmission of the HIV virus from a man to a woman by using a highly concentrated solution of chemical messengers that attract white blood cells to the site of infection.

16 Oct 2004

Discovery of a central memory form of helper T cells that can offer immunity to leishmaniasis

Researchers at the University of Pennsylvania have discovered a "central memory" form of "helper" T cells that can offer immunity to leishmaniasis, a disease that causes considerable death and disfigurement across the globe and has been found in U.S. military personnel returning from Afghanistan and Iraq.

8 Oct 2004

Early use of combination-drug treatments could improve HIV survival rates

Survival rates of HIV-positive patients could be improved if combination-drug treatment were begun earlier than current clinical guidelines now recommend, according to a new study by researchers from The New York Academy of Medicine and the Johns Hopkins University Bloomberg School of Public Health.

14 Sep 2004

Researchers uncover how HIV causes abnormalities in antibody-producing cells

HIV wreaks much of its damage by targeting the “orchestra conductor” of the immune system, a key class of T cells—CD4+ T cells—whose destructive relationship with HIV has been well-studied by AIDS researchers.

8 Sep 2004

Generic tritherapy can be used as a basic treatment for AIDS

A clinical trial, conducted in Cameroon by IRD researchers working with other organizations and supported by the ANRS, has demonstrated that one of the most common combinations currently deployed in Africa, using nevirapine, stavudine and lamivudine, satisfies these criteria.

5 Sep 2004

Counseling for breast cancer patients means healthier diets, reduced smoking and stronger immune systems

Regular psychological counseling for breast cancer patients may do more than just lower their stress and anxiety. A new study says the right kind of intervention can also mean healthier diets, reduced smoking, and most surprising of all – a stronger immune system.

2 Sep 2004

Highly active antiretroviral therapies for AIDS are not initiated soon enough

Highly active antiretroviral therapy (HAART) has been shown to delay progression of AIDS and reduce mortality, yet the optimal time to start it is unknown.

2 Sep 2004

Major trends in AIDS research that the different research teams throughout the world are pursuing

The science will be presented during the conference which is taking place in Lausanne until September 1, 2004. The advances in fundamental research, notably through a better understanding of the complex processes of immune defence, HIV and the functioning of vaccines, promote the genesis and development of new vaccine candidates.

30 Aug 2004

Solid evidence that best treatment for multiple sclerosis is pregnancy

For years, doctors have suggested the best treatment for multiple sclerosis is pregnancy. Now, an Oregon study is delivering solid evidence to support the theory.

27 Aug 2004

FDA reinforces use of Sustiva in first-line HIV combination therapy

Bristol-Myers Squibb has announced that Sustiva® (efavirenz) has received approval from the U.S. Food and Drug Administration to include new long-term virologic and clinical data from BMS Study 006 in its prescribing information.

26 Aug 2004

Genmab's HuMax-CD4 receives U.S. orphan drug designation

Genmab has announced that HuMax-CD4 for the treatment of Mycosis Fungoides (MF), which constitutes 75% of all Cutaneous T-cell Lymphomas (CTCL), has been designated an orphan drug by the US Food and Drug Administration (FDA). The US prevalence of MF is estimated at 16,000 to 20,000.

23 Aug 2004

South Africa will continue providing Nevirapine as monotherapy to mothers and babies

The South African Government's policy to reduce the risk of mother to child transmission of HIV, remains unchanged.

17 Aug 2004

New drug combination more effective than the previous generation of hepatitis C/HIV therapy

A new study reveals the highest efficacy rates ever reported among patients co-infected with hepatitis C and HIV treated with pegylated interferon and ribavirin.

28 Jul 2004