Caenorhabditis elegans News and Research

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Caenorhabditis elegans is a free-living, transparent nematode (roundworm), about 1 mm in length, which lives in temperate soil environments.

Whole-brain imaging data provides insights into roundworm neural activity

Joint research led by Yu Toyoshima and Yuichi Iino of the University of Tokyo has demonstrated individual differences in and successfully extracted commonalities from the whole-brain activity of roundworms.

15 Mar 2024

Researchers identify cold-sensing protein in mammals

University of Michigan researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.

11 Mar 2024

Neuroscientists uncover surprising role of glia in regulating neuronal responses in the brain

Neuroscientists at Fred Hutchinson Cancer Center have found that an often-overlooked type of brain cell called glia has more of a role in brain function than previously thought.

28 Feb 2024

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins-;and ultimately affect aging.

4 Jan 2024

New AI approach captures the tempo and stages of embryonic development

Animal embryos go through a series of characteristic developmental stages on their journey from a fertilized egg cell to a functional organism.

23 Nov 2023

Antibiotics that target mitochondria may promote longevity

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Antibiotics that target mitochondria extend lifespan in C. elegans."

22 Nov 2023

A comprehensive database developed to help understand the basis of protein aggregation

Researchers at the IBB-UAB have developed the most comprehensive database available to date to help understand the basis of protein aggregation, a phenomenon associated with aging and several pathologies.

3 Nov 2023

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

Reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of mitochondrial guanosine-triphosphate.

18 Sep 2023

Kennesaw State professor receives NIH grant to study epigenetic inheritance in nematodes

Kennesaw State University biology professor Brandon Carpenter was inspired to pursue a career in science because of an undergraduate research experience. With a recent grant from the National Institutes of Health (NIH), he'll provide a similar experience to his students.

25 Aug 2023

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

Metformin, the most commonly used drug to treat type 2 diabetes, not only lowers blood sugar levels but has revealed to extend lifespan in C. Elegans -- an animal model that shares similar metabolic systems with humans and are often used to model human diseases.

23 Aug 2023

Mothers' diet during pregnancy can protect brain health of children and grandchildren

Mothers who eat apples and herbs in early pregnancy could be protecting the brain health of their children and grandchildren, a Monash University study using genetic models has found.

3 Aug 2023

New way to attack fungal infections discovered

Researchers at the RIKEN Center for Sustainable Research Science (CSRS) and the University of Toronto have discovered a new way to attack fungal infections.

31 Jul 2023

Tiny amounts of hydrogen sulfide could help people live healthier for longer

Future therapies to help people live healthy lives for longer could be developed from drugs that release tiny amounts of the gas hydrogen sulfide (H2S), new research has indicated.

31 Jul 2023

Robotic system may accelerate studies in diverse areas of C. elegans biology

A robotic system capable of imaging and transferring the model organism Caenorhabditis elegans could replace hours of tedious lab work, according to a recent study.

5 Jul 2023

Does taurine deficiency speed up aging?

The association of the amino acid taurine with aging.

16 Jun 2023

Japanese natto consumption may help realize a healthy and longer-living society

Health is wealth as the saying goes and new research now shows that it is possible to have a healthy, less stressed society through familiar and inexpensive foods.

26 May 2023

Study explores the role of dynamin protein DYN-1 in regenerative axonal fusion

A study explores the role of the dynamin protein DYN-1 in axonal fusion. The axon is a long, thin protrusion of nerve cells that carries electrical impulses.

9 May 2023

Increased expression of collagens can drive longer lifespan at warm temperatures

Researchers have long known that many animals live longer in colder climates than in warmer climates.

4 Apr 2023

Cold temperature plays a central role in longevity

Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging.

3 Apr 2023

New discovery could help target the causes of aging and cancer development

A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered.

23 Mar 2023