Caenorhabditis elegans is a free-living, transparent nematode (roundworm), about 1 mm in length, which lives in temperate soil environments.
Investigators at Case Western Reserve University School of Medicine and University Hospitals Health System have identified a new molecular pathway that controls lifespan and healthspan in worms and mammals.
Two recent Northwestern University studies shed new light on the mystery of the leading cause of birth defects and miscarriage, laying the foundation for further research in an understudied but crucially important field of genetic study.
The heredity substance DNA is the blueprint of our life. Like an instruction manual it contains all the information needed for cells and the body to function properly.
Regular exercise is considered an important form of treatment for heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs.
Scientists reveal that a fault in the process that copies DNA during cell division can cause epigenetic changes that may be inherited for up-to five generations.
Restricting how much you eat without starving has been shown to robustly extend lifespan in more than 20 species of animals including primates.
Many complicated neurological disorders appear to have a gender bias. Women, for example, are more likely to develop Alzheimer's disease, while men are at greater risk for Parkinson's disease.
Microscopic probes developed at Rice University have simplified the process of measuring electrical activity in individual cells of small living animals. The technique allows a single animal like a worm to be tested again and again and could revolutionize data-gathering for disease characterization and drug interactions.
The University of Liverpool has received a £390,000 grant from Medical Research Council to conduct research into how mutations in genes can cause epilepsy.
Programmed cell death is an integral part of embryonic development. Exploring the regulation of the process, Ludwig-Maximilians-Universitaet in Munich researchers have shown that so-called microRNAs protect the precursors of neurons from 'precocious' elimination.
The discovery of a novel protein that links aging and age-dependent retinal diseases could lead to potential new treatments for conditions that cause sight loss in later life.
University of Georgia researchers have found a way to enhance chemotherapy's cancer-killing powers, bringing science one step closer to a more complete cancer treatment.
Researchers from Yale-NUS College have partnered with researchers from the National University of Singapore and SingHealth Group to develop a novel Caenorhabditis elegans (C. elegans) worm strain which expresses an amyloid beta protein fragment involved in the development of human Alzheimer's Disease (AD).
Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are all characterized by clumped, misfolded proteins and inflammation in the brain. In more than 90 percent of cases, physicians and scientists do not know what causes these processes to occur.
Antibiotics save millions of lives. But their tendency to kill helpful and harmful bacteria alike, coupled with the growing problem of antibiotic resistance, means that they are not without their downside.
The genetic information of every cell is encoded in the sequence of the DNA double helix. Double strand breaks in the DNA, which can be induced by radiation, are a dangerous threat to the cells, and if not properly repaired can lead to cancer.
Teams at Ludwig-Maximilians-Universitaet in Munich and EMBL have created photosensitive mimics of a class of signaling molecules, thus enabling their actions to be regulated by light, and affording new insights into the communications networks that control cellular metabolism.
Mitochondrial disorders are a chameleon-like set of diseases that take many different forms and vary widely from individual to individual.
More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them--similarly to how the plastic casing of an electric cable insulates the copper wire within--allowing electrical and chemical impulses to travel faster.
Some cells are meant to live, and some are meant to die. The linker cell of Caenorhabditis elegans, a tiny worm that is a favored model organism for biologists, is among those destined for termination.