Calcification News and Research

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European Congress of Nephrology unveils results of various clinical trials

The 47th ERA-EDTA/DGfN congress in Munich has been the setting for a wide range of new clinical data. The results of the following clinical trials were presented at "Late-Breaking Clinical Trials Sessions."

30 Jun 2010

ADVANCE study provides new insights into the management of SHPT in CKD patients

Results from the ADVANCE study presented in a late breaking clinical trial session at the ERA-EDTA 2010 Congress provide new insights into the management of secondary hyperparathyroidism in chronic kidney disease patients. ADVANCE (A randomiseD VAscular calcificatioN study to evaluate the effects of CinacalcEt) is a randomised, controlled open label study to evaluate the effects of treatment with Mimpara (cinacalcet) plus low-dose vitamin D, compared to flexible doses of vitamin D alone, on the progression of vascular and valvular calcification in dialysis patients with SHPT.

28 Jun 2010

Disorder in degradation of proteins and other macromolecules in cells leads to serious diseases

The degradation of proteins and other macromolecules in cells is vital to survival. Disruption of this process can result in serious disease. The research group of Professor Thomas Jentsch (Leibniz Institute for Molecular Pharmacology, FMP/ Max Delbr-ck Center for Molecular Medicine, MDC, Berlin-Buch) has now succeeded in identifying an essential cellular process necessary for the transport and degradation of macromolecules in endosomes and lysosomes, respectively.

16 Jun 2010

Men with ED are at increased risk of high CACS: Researchers

In the largest study to date evaluating erectile dysfunction and coronary artery calcification, researchers at Mount Sinai School of Medicine have determined that men with ED are at a significantly increased risk of high coronary artery calcification scores, a known predictor of future cardiovascular events.

2 Jun 2010

Significant proportion of men with ED exhibit early signs of CAD: Review

International experts are calling for all men experiencing impotence to undergo thorough medical assessments, after an extensive review showed that a significant proportion of men with erectile dysfunction exhibit early signs of coronary artery disease.

19 May 2010

Researchers explore use of nanomedicine techniques for treatment of diseases in children

"Children are not small adults"—pediatricians say that's what makes their specialty different from the practice of medicine in adults. For similar reasons, researchers exploring the medical uses of nanotechnology believe that the use of molecular-level nanomedicine techniques in children will also require its own specialty.

3 May 2010

Coronary artery calcium score helpful for determining intermediate risk of heart disease

Including a coronary artery calcium score in a risk assessment for future heart disease events, such as heart attacks, provides a better estimate in some populations than a standard coronary risk factors assessment, according to research supported by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health.

28 Apr 2010

High levels of phosphate in sodas accelerate signs of aging

Here's another reason to kick the soda habit. New research published online in the FASEB Journal shows that high levels of phosphates may add more "pop" to sodas and processed foods than once thought. That's because researchers found that the high levels of phosphates accelerate signs of aging. High phosphate levels may also increase the prevalence and severity of age-related complications, such as chronic kidney disease and cardiovascular calcification, and can also induce severe muscle and skin atrophy.

27 Apr 2010

AngioScore receives FDA marketing clearance for PTA Scoring Balloon Catheter

AngioScore, Inc., a developer of novel angioplasty catheters for use in the treatment of cardiovascular disease, announced today that the company has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its AngioSculpt® PTA Scoring Balloon Catheter for dilatation of lesions in renal arteries.

26 Mar 2010

PanGenex finalizes partnership agreement with That’s Us Technologies

PanGenex Corporation a global manufacturer and distributor of nutraceutical and dietary supplement products, announced today that it has finalized a partnership agreement with That’s Us Technologies, Inc. (www.thatsus.com) a marketing company whose exclusive focus is internet marketing.

22 Mar 2010

Research data: WTC collapse caused potentially dangerous heart problems in responders on-site

Researchers from Mount Sinai School of Medicine are presenting more than 20 ground-breaking studies at the American College of Cardiology 59th annual scientific session (ACC.10) in Atlanta. Their research includes data showing that the World Trade Center collapse has caused potentially dangerous heart problems in responders on-site.

17 Mar 2010

NPS Pharmaceuticals supports second annual U.S. Rare Disease Day observance

NPS Pharmaceuticals, a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, announced today its support for the second annual U.S. Rare Disease Day observance on February 28.

1 Mar 2010

PanGenex provides information in response to inquiries about STC

PanGenex Corporation, a global nutraceutical and dietary supplement manufacturer and marketer, today provided information in response to inquiries about Soft Tissue Calcification ("STC") and the Company's products.

22 Feb 2010

Fast method for producing bone and cartilage tissue using body's own cells

Injuries to joints and cartilage can have serious consequences, including osteoarthritis. Cartilage degeneration in joints is a widespread disease in Germany and worldwide. Prof. Dr. Prasad Shastri is an expert in tissue engineering (TE), tissue construction and tissue cultivation using the body's own cells. He is Professor of Biofunctional Macromolecular Chemistry at the Centre for Biological Signalling Studies (BIOSS), a Cluster of Excellence at the University of Freiburg, where he has been researching for the last year.

15 Feb 2010

Air pollution linked to increased risk of atherosclerosis

Researchers at the Keck School of Medicine of the University of Southern California (USC), in collaboration with international partners in Spain and Switzerland and colleagues in California, have found that exposure to air pollution accelerates the thickening of artery walls that leads to cardiovascular disease.

15 Feb 2010

3SBio announces Nephoxil collaboration and license agreement with Panacor Bioscience

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced a collaboration and license agreement with Panacor Bioscience Ltd. to develop and commercialize its Nephoxil(R) pharmaceutical product for the treatment of hyperphosphatemia in China.

8 Feb 2010

High or low blood calcium levels linked to increased risk of premature death in kidney disease patients

Abnormally high or low blood calcium levels are linked to an increased chance of premature death in non-dialysis kidney disease patients, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).

7 Jan 2010

Study reveals patient characteristics can affect image quality of MDCT scans

A large multicenter international trial found that the image quality of multi-detector computed tomography (MDCT) scans, used for the noninvasive detection of coronary artery disease, can be significantly affected by patient characteristics such as ethnicity, body mass index (BMI), and heart rate, according to a study in the January issue of the American Journal of Roentgenology.

23 Dec 2009

Vitamin K2 in Hawaiian Spirulina Pacifica

Cyanotech Corporation, a world leader in microalgae-based, high-value nutrition and health products, today announced its Hawaiian Spirulina Pacifica® has achieved another nutritional first. Already the most nutritious Spirulina in the world, it is also a good source of Vitamin K2.

10 Dec 2009

PanGenex expects release of television program on Calci-CLEAR dietary supplement

PanGenex Corporation announced today that it anticipates the release of its long form television program, demonstrating the benefits of Calci-CLEAR™, its patent pending dietary supplement that addresses soft tissue calcification, pursuant to its partnership with Incredible Discoveries® in early 2010.

28 Nov 2009