Calcitonin News and Research

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Calcitonin is a 32-amino acid linear polypeptide hormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body.

Migraines may hold the key to new treatment for diabetes

The mechanistic association between migraines and type 2 diabetes reveals a new approach to treat diabetes.

26 Aug 2021

Study reveals why mothers take extra risks to protect their children

It might seem like a given that mothers take extra risks to protect their children, but have you ever wondered why? A new study led by Kumi Kuroda at the RIKEN Center for Brain Science (CBS) in Japan shows that in mice, this and other nurturing behaviors are driven in part by neurons in a small part of the forebrain that contain a protein called the calcitonin receptor.

1 Jun 2021

Could procalcitonin indicate bacterial co-infections in COVID-19 patients?

A recent study conducted by Austin Health, Australia, has revealed that the serum level of procalcitonin can be a strong indicator of bacterial co-infection with COVID-19.

18 Jan 2021

Novel drug may help treat osteoporosis, shows study

A novel form of a drug used to treat osteoporosis that comes with the potential for fewer side effects may provide a new option for patients.

6 Jan 2021

Researchers identify possible new therapy for concussion-related headaches

As she jumped to head a soccer ball during her junior year of college, Kelly Farrell collided skulls with a teammate. She later was diagnosed with a concussion, which proved to be severely debilitating.

19 Feb 2020

Seurat publishes preclinical studies of intranasal IGF-1 in rat model of migraine headaches

Seurat Therapeutics, Inc. announced today the publication of preclinical studies of its lead product candidate, intranasal insulin-like growth factor-1 (IGF-1), in a rat model of migraine headaches, in the scientific journal Brain Research.

10 Feb 2020

CALCR neurons may influence long-term control of food intake and body weight

Ever eaten something, gotten sick and then didn't want to eat that food again because of how it made you feel? That's because a signal from the gut to the brain produced that sickness, creating a taste aversion.

17 Jan 2020

A promising cellular target for migraine attacks

A recent study published in the journal Cephalalgia, the official journal of the International Headache Society, reported an intriguing discovery.

17 Dec 2019

Innovative migraine prophylaxis could endanger people with chronic high blood pressure

The neuropeptide αCGRP (α calcitonin gene-related peptide) works in two different ways. It leads to inflammation and dilates the blood vessels right at the release point of the nerve cells, for example in the meninges, which can trigger migraine attacks. However, it has a completely different effect on the heart, as has now been discovered by a team of researchers at the University of Zurich.

26 Nov 2019

New drug 'ubrogepant' may work for migraine

A new study published in the November 19, 2019 issue of JAMA shows that a newly developed small molecule drug called ubrogepant may successfully fight migraine at doses of 25 and 50 mg, with pain relief at 2 hours with both doses, while the most troublesome symptom of migraine was held off at 2 hours post-dose with the 50 mg dose. This may help millions of migraine patients to achieve pain relief and function better.

19 Nov 2019

Experts offer insights into new class of migraine medications

As research continues to show progress towards minimizing the effects of headache disorders on patients' lives, Practical Neurology gathered insights from experts in the field at The American Headache Society 61st Annual Scientific Meeting this year, where new data looking at a range of approaches from nerve stimulation to monoclonal antibodies and neuromodulation devices revealed advancements in migraine treatment.

16 Sep 2019

Melatonin promises to help reduce bone loss in space flight

New research suggests that the problem of bone loss caused by microgravity conditions in space flight may be successfully treated using the time-tested drug melatonin. Melatonin increases the level of calcitonin in bone, which suppresses the bone-destroying activity of osteoclastic cells and helps maintain bone density.

4 Sep 2019

New AAN guidelines includes recommendations for treatment of migraine in children, teens

For children and teens with migraine, the pain and symptoms that accompany migraine attacks can be debilitating, resulting in missed school days, absence from social or sporting events, and affected home activities.

14 Aug 2019

Research may help explain why migraine is more common in women than men

Low doses of a peptide known for decades to be involved in migraine trigger pain responses in female but not male rodents, according to a new research published in JNeurosci.

From Society for Neuroscience 9 Apr 2019

Researchers find new class of blood pressure-regulating peptides in vampire bat venom

Vampire bats could hold the key to new treatments for a range of serious medical problems, but researchers have hit a snag accessing the specimens needed to advance their work.

17 Jan 2019

Novartis: Lancet publishes pioneering study of Aimovig’s efficacy in episodic migraine patients

Novartis announced today that the full data from the LIBERTY study of Aimovig (erenumab) in episodic migraine patients who had tried and failed two to four prior preventive treatments have been published in the Lancet.

23 Oct 2018

New pragmatic study launched to understand the effectiveness of new type 2 diabetes drug

HealthCore, Inc., the outcomes research subsidiary of Anthem, Inc. and Novo Nordisk Inc., which manufacturers the once weekly GLP-1 receptor agonist Ozempic (semaglutide), are working together to launch the first of its kind pragmatic study to understand the benefits of semaglutide as compared with all other available diabetes drugs in a real-world pragmatic clinical trial for Type 2 diabetes - one of the nation's fastest growing chronic diseases.

17 Oct 2018

FDA approves Teva’s AJOVY injection for preventive treatment of migraine in adults

Teva Pharmaceutical Industries Ltd. today announced that the U.S. Food and Drug Administration has approved AJOVY injection for the preventive treatment of migraine in adults.

17 Sep 2018

Research uncovers miscarriage cause, identifies potential targets for treatment

Tragic miscarriages for a couple have led to a discovery with potentially broad implications for future disease treatments, according to a team of researchers at the University of North Carolina School of Medicine. They identified a previously undiscovered gene mutation underlying hydrops fetalis – a fatal condition to fetuses due to fluid buildup in the space between organs.

16 Aug 2018

Scientists examine how specific eating patterns could help fight cancer and obesity

What we eat plays a significant role in our health. The Experimental Biology 2018 meeting (EB 2018) will showcase new research into how diet could be used to fight cancer and how specific eating patterns can encourage weight loss.

23 Apr 2018