Calcium News and Research

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Calcium, the most abundant mineral in the body, is found in some foods, added to others, available as a dietary supplement, and present in some medicines (such as antacids). Calcium is required for muscle contraction, blood vessel expansion and contraction, secretion of hormones and enzymes, and transmitting impulses throughout the nervous system. The body strives to maintain constant concentrations of calcium in blood, muscle, and intercellular fluids, though less than <1% of total body calcium is needed to support these functions.

The remaining 99% of the body's calcium supply is stored in the bones and teeth where it supports their structure. Bone itself undergoes continuous remodeling, with constant resorption and deposition of calcium into new bone. The balance between bone resorption and deposition changes with age. Bone formation exceeds resorption in growing children, whereas in early and middle adulthood both processes are relatively equal. In aging adults, particularly among postmenopausal women, bone breakdown exceeds formation, resulting in bone loss that increases the risk of osteoporosis over time.

New guidelines for treating high blood pressure discounts beta-blockers

Drug treatment for high blood pressure is set to undergo a major shake-up after new guidance was issued for the NHS.

28 Jun 2006

In vitro fertilisation could be causing genetic errors in embryo

The conditions in which embryos are cultured in the laboratory during in vitro fertilisation could be causing genetic errors that are associated with certain developmental syndromes and other abnormalities in growth and development, such as low birth weight.

19 Jun 2006

AUA podium session on stone disease

2-phase randomized crossover study on a constant diet with calcium carbonate supplementation at 250 mg 4 times daily.

13 Jun 2006

Calcium and vitamin D supplements do not reduce breast cancer

A large multicenter randomized clinical trial reported that supplementation with calcium and vitamin D did not reduce breast cancer risk in the overall population.

7 Jun 2006

$Pre-menopausal changes in bone structure may contribute to fracture risk$

Pre-menopausal changes in bone structure may contribute to fracture risk

It is well established that post-menopausal women are at increased risk for developing osteoporosis, but could that be related to subtle pre-menopausal changes in bone structure?

7 Jun 2006

Maternal vitamin D levels and infant bone density

Can bones remember? According to new research presented at the IOF World Congress on Osteoporosis in Toronto, Canada they can.

6 Jun 2006

Bone research in space

On June 2, 2006, space explorers and earth-bound medical experts shared research findings on immobility and bone health at the Bone Research in Space Symposium

5 Jun 2006

Thalomid gets FDA approval to treat multiple myeloma

Thalomid (thalidomide) has been given a new lease of life following the United States Food and Drug Administration (FDA) approval for the drug to be used in combination with the steroid dexamethasone for the treatment of newly diagnosed multiple myeloma.

29 May 2006

Trandolapril and verapamil reduce risk of developing diabetes in Hispanic patients

The combination of drugs traditionally used to control blood pressure might not be ideal for Hispanic patients, University of Florida researchers warn.

23 May 2006

NIH panel says little benefit to be gained by taking multivitamin supplements

According to a National Institutes of Health panel there is little evidence to support that taking multivitamin supplements is of any benefit to healthy adults.

21 May 2006

Panel calls for expanded oversight of vitamin and mineral supplements

An independent panel convened this week by the NIH Office of Medical Applications of Research and the Office of Dietary Supplements assessed the available evidence on the safety and effectiveness of multivitamin/minerals (MVMs).

17 May 2006

Taking astrocytes seriously

By blowing gentle puffs of air onto a mouse's whiskers and watching how its brain reacts, scientists are discovering that a long-overlooked signaling system in the brain is crucial to our everyday activity.

17 May 2006

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia

Long-term therapy with some antiepileptic drugs and antibiotics can cause osteomalacia, a condition marked by softening of the bones that is usually the result of vitamin D and calcium deficiency.

16 May 2006

Signaling pathways in immune cells may lead to novel HIV treatment

New research on signaling pathways in immune cells bolsters evidence of connections between the central nervous system and the immune system.

16 May 2006

European Food Safety Authority says Aspartame quite safe to use

According to the European Food Safety Authority (EFSA), on the basis of all the currently available evidence, a further review of the safety of aspartame is not necessary.

9 May 2006

$Childhood arthritis increases the risk of fractures$

Childhood arthritis increases the risk of fractures

Childhood arthritis increases the risk of fractures, particularly during adolescence, according to a large study of British patient records. The researchers say that more targeted treatments promoting bone health would benefit patients with childhood-onset arthritis throughout their lifespan.

8 May 2006

Polyunsaturated fat and vitamin E halves risk of developing motor neurone disease

A high dietary intake of polyunsaturated fat and vitamin E seems to halve the risk of developing motor neurone disease, suggests research published in the Journal of Neurology Neurosurgery and Psychiatry.

3 May 2006

Forsenol reduces tablet burden on end stage renal disease patients with hyperphospatemia

According to data presented at the National Kidney Foundation's (NKF) 2006 clinical meeting in Chicago, IL, a conversion to the non-calcium phosphate binder FOSRENOL (lanthanum carbonate) from other phosphate binder therapies provides continued mean serum phosphorus control for end-stage renal disease (ESRD) patients with hyperphosphatemia, while significantly reducing their daily tablet burden and the total daily dose of phosphate binder medication.

26 Apr 2006

American women and girls not getting enough calcium

A University of Maryland study shows that while calcium intake is going up in some groups of Americans, teenage girls and young women, especially African Americans, are not getting enough calcium at the time in their lives when calcium is most critical to building bone density.

25 Apr 2006

New method allows heart beat triggers to be viewed and better understood

Researchers have developed unique chemical dyes that have made it possible to see what the naked eye has never seen before: action potentials, or voltage changes, of cardiac cells - including those deep inside the heart, which trigger and determine the pace of heartbeats.

25 Apr 2006