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Bacteria-killing glass offers hope to combat deadliest hospital infections

Scientists at Aston University have discovered a technique similar to medieval stained glass-making that can completely eradicate the deadliest hospital infections within hours.

5 Mar 2019

Research shows how common fungus gets the flexibility to live in different host environments

The fungus Candida albicans is found in the gastrointestinal tract of about half of healthy adults with little if any effect, yet it also causes an oft-fatal blood infection among patients with compromised immune systems, including those with HIV/AIDS.

1 Mar 2019

Researchers unravel how specific intestinal microbiota amplify inflammatory reactions in the lungs

The composition of the microbiome - the countless bacteria, fungi and viruses that colonize our body surface, skin, intestines or lungs - makes a decisive contribution to human health or disease.

23 Feb 2019

Scientists uncover main mechanisms of fluconazole drug resistance

The yeast Candida albicans occurs in most healthy people as a harmless colonizer in the digestive tract. However, it can also cause life-threatening infections, especially in immunocompromised patients.

11 Feb 2019

Study develops simple, new treatment to fight Candida Albicans fungus

A study led by the UPV/EHU has developed an innovative, simple treatment based uterine stem cells to combat the Candida Albicans fungus, responsible for vaginal candidiasis disease.

5 Feb 2019

Insect-borne microbes outperform soil bacteria in stopping certain dangerous antibiotic-resistant pathogens

Medicine was transformed in the 20th century by the discovery and development of antibiotics, the vast majority of which came from one source: soil bacteria.

4 Feb 2019

SCYNEXIS announces positive results from first interim efficacy analysis of FURI study

SCYNEXIS, Inc., a biotechnology company delivering innovative therapies for difficult-to-treat and often life-threatening infections, today announced positive results from the first interim efficacy analysis of the ongoing FURI study.

1 Feb 2019

Peptide isolated from soil fungi has antitumor and antibacterial properties

A team of scientists from I.M. Sechenov First Moscow State Medical University together with their colleagues isolated a peptide named emericellipsin A from soil fungi.

22 Jan 2019

Research finds how Candida albicans adapt to low oxygen levels to cause infection

Scientists from Umeå university have shown how the yeast Candida albicans can modulate and adapt to low oxygen levels in different body niches to cause infection and to harm the host.

16 Jan 2019

Researchers develop mouse model to study consequences of fungal infection in the brain

Fungal infections are emerging as a major medical challenge, and a team led by researchers at Baylor College of Medicine has developed a mouse model to study the short-term consequences of fungal infection in the brain.

4 Jan 2019

White colonies on kimchi surface is not formed by molds but by yeasts, finds study

WiKim reported that the white colonies on the surface of kimchi is not formed by molds but by "yeasts" and that genomic data was acquired regarding the hygienic safety of the yeast strains.

27 Dec 2018

Cloned antibodies show potential to treat, diagnose life-threatening fungal infections

Despite public health efforts, many people who get fungal infections in their blood streams die, even if they can be identified and treated with antifungal drugs. These therapies are often ineffective on their own and increasingly the infections are becoming resistant to treatment with some of the front line antifungal drugs.

11 Dec 2018

Gene sequencing reveals crucial molecular aspects of Trypanosoma brucei

Trypanosoma brucei, which causes sleeping sickness, evades the immune system by repeatedly altering the structure of its surface coat. Sequencing of its genome and studies of its 3D genome architecture have now revealed crucial molecular aspects of this strategy.

19 Oct 2018

Researchers develop new techniques for faster detection of Lyme disease bacteria

Researchers have developed techniques to detect Lyme disease bacteria weeks sooner than current tests, allowing patients to start treatment earlier.

11 Oct 2018

Common herbicide compound could help fight hospital-acquired fungal infections

A chemical compound found in common herbicides could help fight hospital-acquired human fungal pathogenic infections, which claim an estimated two million lives per year.

4 Oct 2018

The Friedrich Schiller University Jena receives funding for Cluster of Excellence

The Friedrich Schiller University Jena (Germany) was granted funding for one Cluster of Excellence. As the Excellence Commission announced today in Bonn, Jena's proposal for the cluster 'Balance of the Microverse' is among the 57 selected consortia which will be funded by the German Excellence Strategy for the following seven years.

28 Sep 2018

Cidara initiates Phase 3 clinical trial to evaluate efficacy, safety of rezafungin to treat invasive candidiasis

Cidara Therapeutics, Inc., a biotechnology company developing novel anti-infectives including immunotherapies, today announced that the first trial site has been activated for ReSTORE, a Phase 3 clinical trial evaluating the efficacy and safety of the company's lead antifungal, rezafungin, to treat candidemia and invasive candidiasis.

27 Sep 2018

Antibiotics actually kill 'good' bacteria and worsen oral infection, finds study

New research shows that the body's own microbes are effective in maintaining immune cells and killing certain oral infections.

26 Sep 2018

Mycovia initiates two Phase 3 clinical trials to evaluate VT-1161 in patients with RVVC

Mycovia Pharmaceuticals, making its official debut as a company developing therapies in women's health and dermatology, today announced the initiation of two Phase 3 clinical trials called VIOLET to evaluate the safety and efficacy of its lead candidate, VT-1161, in patients with recurrent vulvovaginal candidiasis

6 Sep 2018

Dectin-1 pathway could be important new target for treatment of candidiasis, study shows

Candida albicans infection (candidiasis) can cause skin, genital, or oral pain. Many studies have attempted to understand the source of pain in candidiasis; none have provided a clear explanation, until now.

29 Aug 2018