Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

Spanish researchers develop new immunotherapy combination for liver cancer

Spanish researchers at Cima University of Navarra have developed a new immunotherapy combination that improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.

1 Jul 2023

A healthy lifestyle reduces risk of developing severe liver disease

Researchers investigate the correlation between a healthy lifestyle and Life’s Essential 8 scores in new-onset severe non-alcoholic fatty liver disease.

29 Jun 2023

GREB1 gene key to liver cancer development, study finds

The development of hepatocellular carcinoma, liver cancer, is known to involve abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, until now.

27 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

Breakthrough discovery could lead to new treatments for brain metastases

When cancer that starts in the body metastasizes to the brain, it is almost always lethal, in part because so few treatment options exist. Now a new study by Wistar scientists published in Nature Communications shows that a type of brain cell called astrocytes plays an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.

24 Jun 2023

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Dr. Niklas Klümper, resident at the Department of Urology and Pediatric Urology of the University Hospital Bonn (UKB) and working group leader at the Institute for Experimental Oncology (IEO), and Dr. Jonas Saal, resident at the Medical Clinic III for Oncology, Hematology, Immune-Oncology and Rheumatology of the UKB, demonstrated a significant improvement in predicting the response to therapy in metastatic renal cell carcinoma by incorporating the level of inflammation, which was assessed using two straightforward blood parameters, alongside the conventional imaging-based approach.

22 Jun 2023

Pioneering methodology reveals novel biomarkers for non-small cell lung cancer

Researchers of the University of Barcelona and the Institute of Bioengineering of Catalonia have identified new biomarkers for non-small cell lung cancer, the most common lung cancer.

20 Jun 2023

NCCN introduces new global resource to improve thyroid cancer care in low- and middle-income countries

The National Comprehensive Cancer Network® (NCCN®) is introducing a new global resource to improve thyroid cancer care in low- and middle-income countries at the upcoming World Congress on Thyroid Cancer, in London. During the event, NCCN Senior Vice President and Chief Medical Officer, Wui-Jin Koh, MD, will present on NCCN's ongoing global work to define and advance high-quality, high-value, patient-centered cancer care.

14 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Study provides a possible treatment option for prostate cancer resistant to hormone therapy

Prostate cancer is the most-commonly diagnosed malignancy and the second leading cause of cancer death among men in the United States.

12 Jun 2023

Adiposity-associated cancer risk differs based on biological sex

Many studies have linked obesity to an increased risk of cancer, but most have not differentiated the risks between men and women.

12 Jun 2023

Experts investigate the correlation between BORIS mutations and protein expression

A new research paper was published in Oncotarget's Volume 14 on May 26, 2023, entitled, "Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression."

6 Jun 2023

Study assesses the safety, efficacy of using immune checkpoint inhibitors in patients with advanced kidney cancer

Patients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment.

5 Jun 2023

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

At the 2023 American Society for Clinical Oncology Annual Meeting—to be held June 2-6 in Chicago, Illinois—Fred Hutchinson Cancer Center experts will present research spanning survivorship, advances in treatments and clinical trials, how access to cancer care affects outcomes, integrative medicine and more.

5 Jun 2023

Gene alterations in biliary tract cancer offer potential targets for effective precision therapies

Gene alterations in biliary tract cancer offer potential targets for current or future precision therapies. This is demonstrated by a highly acclaimed study conducted by Karl Landsteiner University of Health Sciences in collaboration with the Medical University of Vienna.

5 Jun 2023

Survey reveals the limited knowledge about actinic keratosis among most people

Almirall S.A. (ALM), a global biopharmaceutical company focused on medical dermatology, presented today the results of a survey revealing that 85% of respondents are unaware of the existence of actinic keratosis (AK).

25 May 2023

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Physicians and scientists from the UCLA Jonsson Comprehensive Cancer Center will discuss the latest research and clinical trial results on combination therapies for breast cancer, a potential new treatment for patients with recurrent glioma, and advances in PSMA PET guided radiotherapy for patients with prostate cancer, among other topics, at the American Society of Clinical Oncology's annual meeting.

23 May 2023

Research findings bring order to the genomic chaos of ovarian high grade serous carcinoma

New research findings based on the evolution of malignant tumors increase our understanding of the characteristics of an ovarian cancer subtype that is difficult to treat.

19 May 2023

Identify the underlying mechanism associated with the initiation of focal amplification in breast cancer

Identifying the underlying mechanism associated with the initiation of focal amplification in breast cancer.

19 May 2023

Carcinoma News and Research

Further Reading

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Spanish researchers develop new immunotherapy combination for liver cancer

A healthy lifestyle reduces risk of developing severe liver disease

GREB1 gene key to liver cancer development, study finds

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Breakthrough discovery could lead to new treatments for brain metastases

Study finds new way to predict therapy response in metastatic renal cell carcinoma

Pioneering methodology reveals novel biomarkers for non-small cell lung cancer

NCCN introduces new global resource to improve thyroid cancer care in low- and middle-income countries

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Study provides a possible treatment option for prostate cancer resistant to hormone therapy

Adiposity-associated cancer risk differs based on biological sex

Experts investigate the correlation between BORIS mutations and protein expression

Study assesses the safety, efficacy of using immune checkpoint inhibitors in patients with advanced kidney cancer

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

Gene alterations in biliary tract cancer offer potential targets for effective precision therapies

Survey reveals the limited knowledge about actinic keratosis among most people

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Research findings bring order to the genomic chaos of ovarian high grade serous carcinoma

Identify the underlying mechanism associated with the initiation of focal amplification in breast cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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