Carcinomas News and Research

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Skin cancer rates 350% more than previous estimates suggested, new UK database reveals

Data from the newly established UK skin cancer database, the largest database of its kind in the world, has revealed that there are over 45,000 cutaneous squamous cell carcinomas (cSCC) every year in England, 350 per cent more than previous estimates suggested.

29 Nov 2018

Lower levels of protein make squamous carcinoma cells more invasive

Loss of a protein called TRIM29 promotes cancer cell invasion in a common type of skin cancer, suggesting a novel diagnostic marker and a possible therapeutic target.

21 Nov 2018

Towards finding a druggable cancer target

It's known that cancer involves unchecked cell growth and that a biological pathway that regulates organ size, known at the Hippo pathway, is also involved in cancer.

19 Nov 2018

Scientists equip new virus that kills carcinoma cells with protein

Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system.

19 Nov 2018

Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer

Over 90% of malign tumors in the head and neck are originated from carcinomas of squamous cells that appear in superficial areas of the oral cavity. Their detection with salivary biomarkers can contribute to their early treatment, before they transform into tumors.

14 Nov 2018

Advances in radiation treatment help prolong, improve lives of people with anal cancer

Two recent studies find advances in radiation therapy are helping to prolong or improve the lives of people with anal cancer, including those whose cancer has advanced to stage IV.

8 Nov 2018

Head and neck cancer survivors more likely to commit suicide

Despite improved survival rates among cancer patients, the risk of death by suicide remains high, especially among those treated for head and neck cancers.

25 Oct 2018

Researchers identify genes responsible for sun sensitivity and skin cancer vulnerability

Research carried out at the Health Sciences department of the Universitat Jaume I of Castellón, Spain, has identified the genes responsible for sun sensitivity and skin cancer vulnerability.

25 Oct 2018

Scientists shed light on roles of transcription factors, TP63 and SOX2, in squamous cell carcinoma

Squamous cell carcinomas are aggressive malignancies arising from squamous epithelium of various organs, such as esophagus, head and neck, lung and skin. Previous studies demonstrated that two master transcription factors, TP63 and SOX2, effect genomic activation in SCCs.

15 Oct 2018

Two major studies on canine cancers may provide clues on human cancers

Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors and solid tumors, may be eligible for enrollment.

12 Oct 2018

Study identifies tumor cell population responsible for resistance to therapy and cancer relapse

Resistance to therapy is a major problem in cancer patients as the cells that resist to therapy is at the root of tumor relapse and is associated with high morbidity and mortality.

9 Oct 2018

Not all P53 mutations cause skin cancer

Today, scientists have explained for the first time why not all UV-induced, P53 mutated skin cells develop into cancer.

27 Sep 2018

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

A little p63 goes a long way in embryonic development - and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs.

18 Sep 2018

Cellular environment affects type of tumor development

Liver cancer is the second leading cause of cancer death worldwide. Two different forms of primary liver cancer cover the majority of cases: About 10 to 20 percent of those affected develop a bile duct carcinoma within the liver (intrahepatic cholangiocellular carcinoma; ICC), the far higher proportion of liver cancers are hepatocellular carcinomas.

12 Sep 2018

Carcinomas News and Research

Skin cancer rates 350% more than previous estimates suggested, new UK database reveals

Lower levels of protein make squamous carcinoma cells more invasive

Towards finding a druggable cancer target

Scientists equip new virus that kills carcinoma cells with protein

Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer

Advances in radiation treatment help prolong, improve lives of people with anal cancer

Head and neck cancer survivors more likely to commit suicide

Researchers identify genes responsible for sun sensitivity and skin cancer vulnerability

Scientists shed light on roles of transcription factors, TP63 and SOX2, in squamous cell carcinoma

Two major studies on canine cancers may provide clues on human cancers

Study identifies tumor cell population responsible for resistance to therapy and cancer relapse

Not all P53 mutations cause skin cancer

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

Cellular environment affects type of tumor development

New nuclear medicine imaging method could help diagnose widespread tumors

Researchers identify enzyme that plays vital role in sexual development of fungi

Five microRNAs predict course, recurrence of HPV-negative head and neck cancer

Immune-related enzymes cause aggressive skin cancer in patients with Butterfly Syndrome

Blood biomarker could help predict kidney cancer up to five years prior to diagnosis

Scientists unravel the mystery behind ovarian cancer with high-grade serous carcinoma

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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