Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

FDA nod for pediatric Berlin heart

The U.S. Food and Drug Administration (FDA) has approved the Berlin Heart for pediatric patients waiting for heart transplants. The ventricular assist device is similar to the one worn by former Vice President Dick Cheney but scaled down in size for children and babies.

19 Dec 2011

Study investigates 'missing link' between environmental factors and heart failure

A University of Cambridge study, which set out to investigate DNA methylation in the human heart and the 'missing link' between our lifestyle and our health, has now mapped the link in detail across the entire human genome.

30 Nov 2011

Positive preliminary results from Alnylam's ALN-TTR01 Phase I clinical trial for TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive preliminary results from its Phase I clinical trial with ALN-TTR01, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR).

21 Nov 2011

Stem cell therapy for heart failure: two studies two successes

The Center for Disease Control and Prevention says that heart failure affects nearly 6 million Americans leading to considerable risk of death, diminished quality of like and recurrent hospitalizations. Heart failure occurs when the heart can no longer pump enough blood to the rest of the body. The most common cause of heart failure is coronary artery disease, which narrows the small blood vessels that supply blood and oxygen to the heart.

17 Nov 2011

Women much more likely to suffer from “broken heart syndrome”

Researchers have found that a woman’s heart is broken more easily than a man’s. In fact females are seven to nine times more likely to suffer “broken heart syndrome,” when sudden or prolonged stress like an emotional breakup or death causes overwhelming heart failure or heart attack-like symptoms, the first nationwide study of this finds. Usually patients recover with no lasting damage add researchers.

17 Nov 2011

Alnylam announces new data from ALN-TTR01 Phase I trial on TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it will present new data from its ALN-TTR program at the VIIIth International Symposium on Familial Amyloidotic Polyneuropathy being held in Kumamoto, Japan from November 20-22, 2011.

15 Nov 2011

Fetal stem cells play an important role in inducing maternal cardiac repair

Researchers from Mount Sinai School of Medicine have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury.

14 Nov 2011

Therapeutic hypothermia recommended for patients with preexisting cardiomyopathy

Cardiomyopathy is common among cardiac arrest survivors. The survival and neuroprotective benefits of therapeutic hypothermia is similar in patients with preexisting cardiomyopathy, compared with those patients without cardiomyopathy, according to a scientific poster being presented Nov. 14 at the American Heart Association (AHA) scientific sessions.

14 Nov 2011

Data shows cost-effectiveness of ZOLL LifeVest Wearable Defibrillator

ZOLL Medical Corporation, a manufacturer of medical devices and related software solutions, announced today that data showing the cost-effectiveness of the LifeVest Wearable Defibrillator was presented in two scientific presentations and posters at the American Heart Association's Scientific Sessions 2011 in Orlando over the weekend.

14 Nov 2011

Hypertrophic cardiomyopathy is consistent with survival to normal life expectancy

Hypertrophic cardiomyopathy (HCM) is consistent with survival to normal life expectancy, including particularly advanced age into the tenth decade of life, with demise ultimately largely unrelated to this disease, according to a study being presented Nov. 13 at the American Heart Association (AHA) scientific sessions in Orlando, Fla.

14 Nov 2011

Oncostatin M could help heal damaged heart muscle tissue

Oncostatin M regulates the reversion of heart muscle cells into precursor cells and is vitally important for the self-healing powers of the heart

11 Nov 2011

Treatments can help most HCM patients

Most of the 600,000 Americans with hypertrophic cardiomyopathy (HCM) -- a genetic heart muscle disease -- can live normal life spans, according to the first science-based guideline for diagnosing and treating this disorder.

9 Nov 2011

Role of cardiovascular magnetic resonance in clinical cardiology

Cardiovascular Magnetic Resonance (CMR) has undergone substantial development and offers important advantages compared with other well-established imaging modalities.

3 Nov 2011

Broader screening for hypertrophic cardiomyopathy

Around one in 500 Swedes carry a genetic mutation which can cause sudden cardiac death. The diagnosis can lead to major lifestyle changes, but quality of life can be maintained with the right advice and support, reveals a new study from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

2 Nov 2011

More than 50,000 patients at high risk of SCA have been prescribed ZOLL's LifeVest

ZOLL Medical Corporation, a manufacturer of medical devices and related software solutions, announced today that more than 50,000 patients at high risk of sudden cardiac arrest (SCA) have been prescribed the LifeVest Wearable Defibrillator.

29 Oct 2011

Potential avenue to make an unhealthy heart grow more like a healthy version

Identification of three fatty acids involved in the extreme growth of Burmese pythons' hearts following large meals could prove beneficial in treating diseased human hearts, according to research co-authored by a University of Alabama scientist and publishing in the Oct. 28 issue of Science.

28 Oct 2011

Experts from CHOP address American Academy of Pediatrics annual meeting

Numerous experts from The Children's Hospital of Philadelphia will be addressing their colleagues at this year's annual meeting of the American Academy of Pediatrics on topics as varied as vaccine education, fetal surgery, sudden cardiac arrest, and sports injuries, among others.

15 Oct 2011

European and North American scientists to explore biology of heart failure

A collaborative network of European and North American scientists, including from the University of North Carolina at Chapel Hill School of Medicine, have been awarded a total of $6 million over five years to explore the biology of heart failure and to find new therapies for it.

1 Oct 2011

Study helps predict which ARVD patients are at highest risk of sudden cardiac death

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22 Sep 2011

NIH awards $12.8 million renewal grant for Louisville adult stem cell research project

At the time when Dr. Roberto Bolli received word that he was awarded a $12.8 million grant renewal from the National Institutes of Health for one research project, five patients in another of his clinical trials at the University of Louisville have reached the successful endpoint of their participation.

9 Sep 2011

Cardiomyopathy News and Research

Further Reading

FDA nod for pediatric Berlin heart

Study investigates 'missing link' between environmental factors and heart failure

Positive preliminary results from Alnylam's ALN-TTR01 Phase I clinical trial for TTR-mediated amyloidosis

Stem cell therapy for heart failure: two studies two successes

Women much more likely to suffer from “broken heart syndrome”

Alnylam announces new data from ALN-TTR01 Phase I trial on TTR-mediated amyloidosis

Fetal stem cells play an important role in inducing maternal cardiac repair

Therapeutic hypothermia recommended for patients with preexisting cardiomyopathy

Data shows cost-effectiveness of ZOLL LifeVest Wearable Defibrillator

Hypertrophic cardiomyopathy is consistent with survival to normal life expectancy

Oncostatin M could help heal damaged heart muscle tissue

Treatments can help most HCM patients

Role of cardiovascular magnetic resonance in clinical cardiology

Broader screening for hypertrophic cardiomyopathy

More than 50,000 patients at high risk of SCA have been prescribed ZOLL's LifeVest

Potential avenue to make an unhealthy heart grow more like a healthy version

Experts from CHOP address American Academy of Pediatrics annual meeting

European and North American scientists to explore biology of heart failure

Study helps predict which ARVD patients are at highest risk of sudden cardiac death

NIH awards $12.8 million renewal grant for Louisville adult stem cell research project

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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