Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Researchers develop realistic replica of adult human ear using 3D printing

Using state-of-the-art tissue engineering techniques and a 3D printer, researchers at Weill Cornell Medicine and Cornell Engineering have assembled a replica of an adult human ear that looks and feels natural.

29 Mar 2024

Exploring the link between prenatal nutrition and congenital craniofacial malformations

The complex development of craniofacial skeletal structures and improve treatments for congenital craniofacial malformations.

27 Mar 2024

Columbia researchers secure $38.95 million ARPA-H contract to build a living knee replacement

A team of researchers from Columbia University Irving Medical Center and Columbia Engineering has been awarded up to a $38.95 million contract from the Advanced Research Projects Agency for Health (ARPA-H) to build a living knee replacement from biomaterials and human stem cells, including a patient's own cells.

26 Mar 2024

New project aims to engineer live joints for osteoarthritis treatment

About 32.5 million people in the United States and 500 million globally suffer from the degenerative joint disease known as osteoarthritis (OA), according to the Centers for Disease Control.

26 Mar 2024

Study highlights growing burden of neurological disorders worldwide

Globally, the number of people living with, or dying from, neurological conditions such as stroke, Alzheimer's disease and other dementias, and meningitis has risen substantially over the past 30 years due to the growth and aging of the global population as well as increased exposure to environmental, metabolic, and lifestyle risk factors.

15 Mar 2024

New method simplifies production of limb progenitor cells from fibroblasts

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

4 Mar 2024

Calcium crystal deposits linked to worsening knee osteoarthritis, study finds

Knee osteoarthritis (OA) is the most common form of arthritis, affecting approximately 600 million people worldwide and 34 million people in the U.S.

28 Feb 2024

Innovative electrospinning technique yields 3D scaffolds for skin cells

A new technique for electrospinning sponges has allowed scientists from the University of Surrey to directly produce 3D scaffolds - on which skin grafts could be grown from the patient's own skin.

23 Feb 2024

Nose cartilage-based knee joint treatment project receives €2.3 million funding

Treating knee joint defects with cartilage from the nose: The University Hospital in Würzburg is working on the approval of this procedure.

21 Feb 2024

Meniscal coverage offers clue to painful discoid lateral meniscus

With all of the fantastic imaging techniques available in healthcare today, clinicians are capable of diagnosing tissue and joint deformities using non-invasive imaging with remarkable accuracy.

7 Feb 2024

"Cleaning cell" dysfunction explains unequal diabetes risk in obesity

Disrupted function of "cleaning cells" in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not.

5 Feb 2024

New study unlocks secrets to preventing birth defects

Cleft lip and palate are the most common craniofacial birth defects in humans, affecting more than 175,000 newborns around the world each year.

22 Jan 2024

WFIRM leads $40M regenerative medicine initiative for the wounded and beyond

The Wake Forest Institute for Regenerative Medicine, part of Wake Forest University School of Medicine, has been selected to lead the Armed Forces Institute of Regenerative Medicine (AFIRM) Consortium.

22 Jan 2024

New discovery sheds light on the genetic basis of a rare skeletal disorder

A McGill-led team of researchers have made an important discovery shedding light on the genetic basis of a rare skeletal disorder.

19 Jan 2024

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

A new study in Nature described Nav1.7 as a key regulatory molecule in cartilage cells and reported the effectiveness of Nav1.7 blockade in reducing pain and slowing progression in OA.

5 Jan 2024

YAP and TAZ proteins guide bone development in the womb

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

4 Jan 2024

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

3 Jan 2024

UCSF appoints renowned surgeon and researcher Dr. Benjamin Ma as chair of orthopedic surgery

Benjamin Ma, MD, a highly regarded orthopedic surgeon and advanced imaging researcher, has been appointed as chair of the UCSF Department of Orthopaedic Surgery. Ma will assume his new role on January 1, 2024.

25 Dec 2023

Sirtuin 6: A potential savior for aging cartilage and osteoarthritis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes."

19 Dec 2023