Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Study generates a comprehensive genetic map to identify important genes that cause sarcoma

Several genes that cause sarcoma have been identified in the first comprehensive genetic map of sarcomas, generated by research led by Omico, the Garvan Institute of Medical Research and UNSW Sydney.

19 Jan 2023

Reconstructing MRI scans with AI promises to expand MRI access to more patients

Artificial intelligence (AI) can reconstruct coarsely-sampled, rapid magnetic resonance imaging (MRI) scans into high-quality images with similar diagnostic value as those generated through traditional MRI, according to a new study by the NYU Grossman School of Medicine and Meta AI Research.

17 Jan 2023

Excessive mechanosensation in sensory neurons can cause joint deformities

Excessive mechanosensation in the neurons that enable the sense of one's limbs in space can disrupt musculoskeletal development and cause joint deformities like arthrogryposis, researchers report.

12 Jan 2023

Researchers demonstrate the role of Klotho protein in the formation of osteoarthritis

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity.

10 Jan 2023

Circulating microparticle proteins predict placenta accreta spectrum before delivery

A recent study published in the journal Scientific Reports reported that circulating microparticle (CMP) proteins predict pregnancies complicated by placenta accreta spectrum (PAS).

9 Jan 2023

3D neutron tomography reveals water diffusion across the bone material

What keeps bones able to remodel themselves and stay healthy? A team from Charité Berlin has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load.

22 Dec 2022

Recapitulating early stages of the human body plan in a dish

Although Michelangelo's masterpiece David captured the magnificence of the human body - how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century.

21 Dec 2022

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

A collaborative team, which includes scientists from the Terasaki Institute for Biomedical Innovation, University of Illinois Chicago, and Pohang University of Science and Technology has elucidated some key points on how the generation of cartilage in the joints is facilitated and how alternative bone formation can be avoided.

21 Dec 2022

Low-intensity ultrasound therapies may help rebuild stronger knees

Low-intensity ultrasound therapies may one day rebuild stronger knees following injury or surgery, thanks to research by Dr. Anu Subramanian at The University of Alabama in Huntsville (UAH) that's being supported by the National Institutes of Health.

7 Dec 2022

Study suggests new strategies for making cartilage cells

As any weekend warrior understands, cartilage injuries to joints such as knees, shoulders, and hips can prove extremely painful and debilitating. In addition, conditions that cause cartilage degeneration, like arthritis and temporomandibular joint disorder (TMJ), affect 350 million people in the world and cost the US public health system more than $303 billion every year.

30 Nov 2022

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Corticosteroid injections associated with progression of knee osteoarthritis

Two studies comparing injections commonly used to relieve the pain of knee osteoarthritis found that corticosteroid injections were associated with the progression of the disease.

29 Nov 2022

Anti-inflammatory pain relievers may worsen inflammation in osteoarthritis

Taking anti-inflammatory pain relievers like ibuprofen and naproxen for osteoarthritis may worsen inflammation in the knee joint over time, according to a new study being presented next week at the annual meeting of the Radiological Society of North America.

21 Nov 2022

Gene may play a broader role in embryonic organ development

An international study led by the medical Faculty of the University of Bonn has identified a gene that plays an important role in the development of the human embryo. If it is altered, malformations of various organ systems can result.

15 Nov 2022

Study finds a possible new target to fight osteoarthritis

Wear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis.

14 Oct 2022

Researchers identify a new gene implicated in rare lysosomal storage disorder

In a rare disease called mucolipidosis type II, people’s hearts and abdomens swell, and their bones grow malformed.

6 Oct 2022

Researchers find new way to deliver a protein quickly, effectively and briefly to the brain

Many diseases have at their origin a protein that does not function properly. Now, a multidisciplinary research team with Texas A&M AgriLife and Texas A&M University has found a way to deliver a protein quickly, effectively and briefly to the brain, with therapeutic and scientific implications.

28 Sep 2022

New modeling technique can help better understand the development of rheumatoid arthritis

A new modeling technique can better predict how bones, cartilage, and cellular tissues will be affected by rheumatoid arthritis in small joints.

28 Sep 2022

Research pits the simulation of beta radiation in cancer treatment against analytical method

A new paper published in EPJ Plus and authored by Eduardo De Paiva, from the Division of Medical Physics at the Institute of Radiation Protection and Dosimetry, Rio de Janeiro, Brazil, pits the gold standard simulation method used to calculate the interaction of the ionizing radiation with matter and estimate the radiation dose delivered to a target organ—Monte Carlo (MC) simulation — against an alternative analytic method, the Loevinger formula.

20 Sep 2022

OU researcher may have found a way to reduce the number of TBI surgeries to just one

A battered woman. A wounded warrior. A football player. All from completely different worlds. Yet, all are connected by one thing – traumatic brain injury.