Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Menstrual stem cells may help in treatment of stroke and central nervous system disorders

Cryo-Cell International, Inc. today announced results of a study published this month in the cover article of Stem Cells and Development showing that stem cells found in menstrual blood may one day be a potential source for stem cell therapies in stroke and other central nervous system disorders.

5 Apr 2010

Multnomah Court Judge denies I-Flow's request for new trial

Judge Youlee You today denied a request by defendant I-Flow for a new trial in Multnomah County Circuit Court. The ruling follows the January 22 jury verdict against the pain pump manufacturer. Jurors awarded $5.475 million for the destruction of Portland-area resident Matthew Beale's right shoulder. They found the damage was caused by the On-Q Painbuster infusion pain pump, manufactured and marketed by I-Flow.

2 Apr 2010

Positive results from Phase 2 clinical trial of OMS103HP

Omeros Corporation today announced that a Phase 2 clinical trial of OMS103HP, its PharmacoSurgery™ product candidate for arthroscopy, demonstrated that patients treated with OMS103HP during arthroscopic knee meniscectomy surgery achieved statistically significant clinical benefits.

1 Apr 2010

$Notch pathway could aid treatment of osteoporosis, fractures and arthritis$

Notch pathway could aid treatment of osteoporosis, fractures and arthritis

Scientists seeking new ways to fight maladies ranging from arthritis and osteoporosis to broken bones that won't heal have cleared a formidable hurdle, pinpointing and controlling a key molecular player to keep stem cells in a sort of extended infancy.

31 Mar 2010

Study: Hormone replacement in joint fluid might be beneficial in treating osteoarthritis

German researchers determined that concentrations of the sex hormones, testosterone in men and estrogen in women, may have a positive effect on the regenerative potential of cartilage tissue. The study suggests hormone replacement in the joint fluid of men and women might be beneficial in treating late stages of human osteoarthritis by regenerating damaged tissue.

30 Mar 2010

New minimally invasive surgery to correct chest wall deformity demonstrated at international conference

A new minimally invasive surgery to correct a chest wall deformity -- often known as pigeon chest -- was demonstrated Friday at an international conference attended by surgeons from the U.S., Canada, Argentina, Chile, Panama, Puerto Rico, Germany, Spain and Russia.

27 Mar 2010

New device detects bacterial and fungal contamination

Microorganisms are everywhere and most of them are harmless, but they can do a lot of damage in the manufacture of pharmaceuticals or in tissue transplants. With the aid of a new device, germs can be detected in artificial cartilage within a few hours.

20 Mar 2010

Bone Biologics receives Notice of Allowance of patent claims that protects formation of cartilage by UCB-1

Bone Biologics, Inc. announced today that it has received a US Patent Office Notice of Allowance of patent claims which strongly protects the formation of cartilage by the unique NELL 1 protein (UCB-1). Additional claims cover the surgical application of the NELL 1 (UCB-1) protein by several delivery agents.

18 Mar 2010

Researchers explore new tools to mitigate risk of radiation exposure

Doctors have a clearer picture than ever before of how much radiation reaches sensitive tissues during routine X-rays and similar imaging, thanks to sophisticated models of the human body being developed at the University of Florida.

17 Mar 2010

Viron Therapeutics' VT-346 anti-TNF protein exhibits positive results in transgenic mouse model for arthritis

Viron Therapeutics Inc. announced that VT-346, an anti-TNF protein therapeutic, demonstrated positive results in a pivotal proof of concept study in the gold standard transgenic mouse model for arthritis. VT-346 achieved a statistically significant, dose dependent impact in this preclinical model of arthritis and prevented deterioration due to disease in terms of weight gain, arthritic score and pathology parameters. VT-346 had particularly strong protective effects on therapeutically-important bone and cartilage damage in this model.

16 Mar 2010

AlloSource receives US patent for cleaning and disinfecting system

AlloSource, one of the nation's largest non-profit providers of skin, bone and soft tissue allografts for use in surgical procedures and the world's largest processor of live cellular bone growth substitutes, has been awarded its first patent for a propriety tissue cleaning and disinfecting process called RICA.

16 Mar 2010

Torn meniscus repair with simultaneous ACL reconstruction successful in 84% children

Eighty-four percent of children 18 and younger had successful clinical outcomes during an eight year follow-up to repair a torn meniscus (cartilage that provides cushioning to distribute your body weight across the knee joint) at the same time as reconstruction of the anterior cruciate ligament (ACL), according to a new study presented today at the American Orthopaedic Society for Sports Medicine's Specialty Day in New Orleans, (March 13).

15 Mar 2010

TKR relieves pain and improves balance in elderly patients with advanced knee arthritis

Total knee replacement successfully relieves pain and improves function in patients with advanced knee arthritis, according to a study presented today at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). The surgery also significantly improves dynamic balance among elderly patients.

12 Mar 2010

Researchers identify a novel source of adult stem cells: Foreign body-induced granulation tissue

In a pioneering new study published in the journal Translational Research, Dr. Jilpa Patel and her research group at Hektoen Institute of Medicine and Cook County Hospital in Chicago have isolated and characterized adult stem cells from granulation tissue in rats. A granulation tissue is a new regenerating tissue formed in response to an inert foreign body placed in the subcutaneous tissue.

11 Mar 2010

BIDMC scientist presented with 2010 Arthur Steindler Award

Christopher Evans, PhD, director of the Center for Advanced Orthopaedic Studies at Beth Israel Deaconess Medical Center and Maurice Edmond Mueller Professor of Orthopaedic Surgery at Harvard Medical School, was presented with the 2010 Arthur Steindler Award at this week's annual meeting of the Orthopaedic Research Society in New Orleans.

11 Mar 2010

Forteo therapy may speed healing, improve patient outcomes after rotator cuff surgery

Tears in the shoulder's rotator cuff, a common sports injury, are painful and restricting. Surgery to repair the damage is successful for pain management, but in many patients it does not result in full recovery of function due to poor healing. New research shows an approved therapy for osteoporosis, Forteo, may speed healing and improve patient outcomes.

11 Mar 2010

RTI Biologics launches BTB Select and BioCAP Select implants for use in sports medicine surgeries at AAOS 2010

RTI Biologics Inc., the Florida-based processor of orthopedic, dental, surgical specialties and other biologic implants, is launching two new biologic implants for use in sports medicine surgeries at the American Academy of Orthopaedic Surgeons annual meeting in New Orleans this week.

11 Mar 2010

Orthopedic surgeons focus on new ways to prevent arm injuries among young baseball players

Throwing arm injuries are on the rise in Little League and other youth baseball programs. After these injuries occur, many players are out for the season; others require surgery and must refrain from play for an even longer duration; still others sustain injuries so severe that they cause permanent damage and are unable to continue playing baseball.

11 Mar 2010

AAOS 2010 meeting highlights emerging incidence of pediatric sports injuries

At today's 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), two separate studies focus on the dramatic rise of pediatric sports injuries in recent years. However, despite this alarming trend, awareness, education, warning signs and early treatment can make a significant difference and help keep these athletes in the game, according to the study experts.

11 Mar 2010

Smith & Nephew introduces BIORAPTOR Knotless Suture Anchor

Smith & Nephew's Endoscopy Division today announced the launch of the BIORAPTOR™ Knotless Suture Anchor, a device used to repair a torn labrum in the hip and shoulder. The anchor is among products featured at the American Academy of Orthopaedic Surgeons annual meeting, which began today in New Orleans.

10 Mar 2010

Cartilage News and Research

Further Reading

Menstrual stem cells may help in treatment of stroke and central nervous system disorders

Multnomah Court Judge denies I-Flow's request for new trial

Positive results from Phase 2 clinical trial of OMS103HP

Notch pathway could aid treatment of osteoporosis, fractures and arthritis

Study: Hormone replacement in joint fluid might be beneficial in treating osteoarthritis

New minimally invasive surgery to correct chest wall deformity demonstrated at international conference

New device detects bacterial and fungal contamination

Bone Biologics receives Notice of Allowance of patent claims that protects formation of cartilage by UCB-1

Researchers explore new tools to mitigate risk of radiation exposure

Viron Therapeutics' VT-346 anti-TNF protein exhibits positive results in transgenic mouse model for arthritis

AlloSource receives US patent for cleaning and disinfecting system

Torn meniscus repair with simultaneous ACL reconstruction successful in 84% children

TKR relieves pain and improves balance in elderly patients with advanced knee arthritis

Researchers identify a novel source of adult stem cells: Foreign body-induced granulation tissue

BIDMC scientist presented with 2010 Arthur Steindler Award

Forteo therapy may speed healing, improve patient outcomes after rotator cuff surgery

RTI Biologics launches BTB Select and BioCAP Select implants for use in sports medicine surgeries at AAOS 2010

Orthopedic surgeons focus on new ways to prevent arm injuries among young baseball players

AAOS 2010 meeting highlights emerging incidence of pediatric sports injuries

Smith & Nephew introduces BIORAPTOR Knotless Suture Anchor

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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