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Horizon Discovery adds predesigned synthetic single guide RNA to its product range

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announced the addition of predesigned synthetic single guide RNA (sgRNA) to its product range.

From Revvity 13 Dec 2019

Harvard scientists demonstrate possible strategy for achieving herpes virus control

The herpes simplex virus, commonly known as the cold sore virus, is a devious microbe.

12 Dec 2019

ERC promotes CRISPR research to better treat infections

Chase Beisel heads the "Synthetic Biology of RNA" research group at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a branch of the Helmholtz Centre for Infection Research in Braunschweig and run in collaboration with the Julius-Maximilians-Universität in Würzburg.

10 Dec 2019

Study shows how a new combination approach helps overcome resistance to cancer immunotherapy

Cancer immunology drugs, which harness the body's immune system to better attack cancer cells, have significantly changed the face of cancer treatment. People with aggressive cancers are now living longer, healthier lives. Unfortunately, cancer immunology therapy only works in a subset of patients.

9 Dec 2019

Research shows link between clock genes and vitamin A pathway in the brain of Monarch butterflies

Biologists at Texas A&M University are making strides in understanding biological clock function in several model organisms and translating these studies into broader implications for human health.

6 Dec 2019

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a new study in the Nature journal Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process.

6 Dec 2019

Experts condemn CRISPR babies research as original manuscript is made public

Scientists have criticized the gene-editing of the Chinese twins last year, following the first public release of the research.

4 Dec 2019

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Along with the promise that CRISPR-Cas9 gene editing technology can offer new human therapies is the need to ensure its safety. A recent study showed that CRISPR-Cas9 did not produce off-target gene mutations in zebrafish. These results, published in Frontiers in Genetics, confirm previous data in animal models that the risk to the rest of the genome from gene editing is minimal.

3 Dec 2019

New molecular mechanism involved in the regulation of cholesterol movement in cells found

Researchers from the University of Barcelona and the August Pi i Sunyer Biomedical Research Institute found a new molecular mechanism involved in the regulation of the cholesterol movement in cells, an essential process for a proper cell functioning.

2 Dec 2019

Mystery surrounds gene edited babies one year on

A year back Chinese scientist He Jiankui was in the news for all the wrong reasons. He had helped create the world’s first genetically edited human babies. After a year the world is still in dark about the whereabouts and health of the babies he had created and he himself has been not seen since January this year.

27 Nov 2019

Scientists discover new approach to treating incurable leukemia in children

Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people.

25 Nov 2019

Researchers discover molecular underpinnings of Alexander disease

Scientists have known that genetic mutations leading to the production of a defective protein called GFAP cause Alexander disease (AxD), a debilitating neurodegenerative condition that can present during infancy, adolescence, or adulthood.

21 Nov 2019

Machine learning successfully replicates cell architecture

A new study reports the use of machine learning to help form complex cell architectures from pluripotent stem cells.

21 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

New computational model could help in the development of anti-cancer drugs

Researchers from the Faculty of Medicine and the Institute for Molecular Medicine at the University of Helsinki have developed a computational model, Combined Essentiality Scoring (CES) that enables accurate identification of essential genes in cancer cells for development of anti-cancer drugs.

14 Nov 2019

CRIPSR could be used to detect disease

CRISPR could be used to establish new diagnostic blood tests by identifying viral nucleic acids, such as Parvo or HPV.

11 Nov 2019

New point-of-care medical device rapidly and accurately detects viruses

The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer, or decried as "the genetic scissors that tailor the human gene pool," an ethically risky technology driving us toward a designer babies.

11 Nov 2019

Improved gene editing technique can successfully cut out undesirable genetic information

City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information.

7 Nov 2019

CRISPR-Cas9 protein can help increase targeting accuracy in genome editing process

A team of researchers from City University of Hong Kong and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for future gene therapies in human, which require high precision.

6 Nov 2019

Gene-editing technique CRISPR trialed for first time as cancer treatment

The go-ahead has been given for the first trials using CRISPR as an alternative therapy for treating cancer.